2021 American Transplant Congress
Living Donor Liver Transplant for Unresectable Colorectal Metastasis: A Case Series
Starzl Transplant Institute, UPMC, Pittsburgh, PA
*Purpose: Colorectal Cancer (CRC) represents the third most common malignancy worldwide. In the US, CRC lifetime risk is approximately 1 in 23 (4.4%) for men…2021 American Transplant Congress
Risk Factors Predicting Outcomes in Long-Term Pediatric Kidney Transplant Graft Survival
Baylor College of Medicine, Houston, TX
*Purpose: Pediatric kidney transplant recipients generally have good outcomes post-transplantation; however, the younger age and longer lifespan after transplantation in the pediatric population make understanding…2021 American Transplant Congress
T Cell Repertoire Diversity in HCV-Associated Hepatocellular Carcinoma Patients Waitlisted for Liver Transplantation and Receiving Liver-Directed Therapy
Ochsner Health, New Orleans, LA
*Purpose: T cell receptor (TCR) sequencing in hepatocellular carcinoma (HCC) patients revealed a diverse TCR repertoire in hepatitis B-associated HCC-infiltrating T cells. In this study,…2021 American Transplant Congress
Drivers of Graft Failure in Pediatric Kidney Transplant Change Over Time
*Purpose: Short-term pediatric kidney transplant outcomes have improved over time with advanced surgical techniques and better immunosuppression, but long-term graft outcomes remain suboptimal - concerning…2021 American Transplant Congress
Allograft Discard Risk Index for Lung Transplantation
Baylor College of Medicine, Houston, TX
*Purpose: The demand for donor lungs continues to outpace the supply, yet nearly 80% of donor lungs consented for lung transplantation (LTx) are discarded.*Methods: We…2021 American Transplant Congress
The Impact of 4-weeks of Supervised Exercise on Frailty and Lower Extremity (LE) Function in Patients with Advanced Chronic Kidney Disease (CKD)
*Purpose: Although frailty is a modifiable risk factor for morbidity and mortality among kidney transplant (KT) candidates, the optimal duration of effective prehabilitation interventions is…2021 American Transplant Congress
NASH-Related HCC is Associated with Lower Rates of Post-Transplant HCC Recurrence: A Large Database Analysis
Department of Surgery, Thomas Jefferson University, Philadelphia, PA
*Purpose: As incidence of hepatocellular carcinoma (HCC) and Non-Alcoholic Steatohepatitis (NASH) increase, NASH-related HCC is an increasingly common transplant indication. Large-scale studies evaluating transplantation for…2021 American Transplant Congress
Liver Kinase B1 Knockdown Induces Platelet-Derived Growth Factor Receptor B Expression in Human Airway Epithelial Cells: A Potential Mechanism for Development of Fibrosis Leading to Chronic Lung Allograft Dysfunction
St. Joseph’s Hospital and Medical Center, Phoenix, AZ
*Purpose: The platelet-derived growth factor and its receptor (PDGFRb) signaling pathway can be activated by epithelial mesenchymal transition which facilitates fibrosis. It is not known…2021 American Transplant Congress
Assessing the Accuracy of the Lung Allocation Score
1University of Chicago, Chicago, IL, 2University of Wisconsin-Madison, Madison, WI
*Purpose: The Lung Allocation Score (LAS) relies on the performance of two cox proportional hazards models that estimate waitlist and post-transplant survival. These models were…2021 American Transplant Congress
Plasma Donor-Derived Cell-Free DNA Levels Risk-Stratify Kidney Allograft Injury with Isolated Transplant Glomerulitis
*Purpose: The Banff lesion Glomerulitis (g) characterizes the degree of microvascular glomerular inflammation. Some studies have demonstrated glomerulitis in the absence of C4d in association…
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