ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    AM PAC Scores and Liver Transplant Resource Utilization

    M. Pierpont1, M. Gosselin2, K. Robichaux3, A. Kumar1, J. Buggs4, N. Kemmer5

    1Morsani College of Medicine, University of South Florida, Tampa, FL, 2Honors College, University of Tampa, Tampa, FL, 3Honors College, University of South Florida, Tampa, FL, 4Transplant Surgery, Tampa General Hospital, Tampa, FL, 5Transplant Hepatology, Tampa General Hospital, Tampa, FL

    *Purpose: Activity Measure for Post-Acute Care (AM-PAC) is a tool utilized to assess three functional domains: basic mobility, daily activities, and applied cognition. Previous studies…
  • 2021 American Transplant Congress

    The Survival Benefits of Using Marginal Allografts in Liver Transplantation

    T. H. Malik1, E. L. Godfrey1, A. Rana2

    1Baylor College of Medicine, Houston, TX, 2Department of Abdominal Transplantation, Baylor College of Medicine, Houston, TX

    *Purpose: Our study assessed whether using marginal allografts at initial time of listing provided similar or greater survival benefit versus waiting on the transplant waitlist…
  • 2021 American Transplant Congress

    T Cell Repertoire Diversity in HCV-Associated Hepatocellular Carcinoma Patients Waitlisted for Liver Transplantation and Receiving Liver-Directed Therapy

    K. Nunez, T. Sandow, A. Cohen, P. Thevenot

    Ochsner Health, New Orleans, LA

    *Purpose: T cell receptor (TCR) sequencing in hepatocellular carcinoma (HCC) patients revealed a diverse TCR repertoire in hepatitis B-associated HCC-infiltrating T cells. In this study,…
  • 2021 American Transplant Congress

    Leflunomide Therapy for Treatment of Bk Viremia in Pediatric Kidney Transplant Recipients

    A. Aldieri1, M. Chandran2, D. Matossian3, B. Magella4, D. Lazear4, M. Bock2, E. Blanchette2

    1Children's Hospital Colorado, Denver, CO, 2Children's Hospital Colorado, Aurora, CO, 3Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 4Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    *Purpose: BK viremia (BKV) after kidney transplantation (KT) poses significant risk for BK virus-associated nephropathy (BKVN) and impacts graft survival. Conventional treatment involves reduction of…
  • 2021 American Transplant Congress

    Adjuvant Immunotherapy for Liver Transplant Recipients with Hepatocellular Carcinoma Using Donor Liver-derived Natural Killer Cells

    M. Ohira1, R. Hotta1, Y. Imaoka1, K. Sato1, N. Tanimine1, Y. Tanaka1, S. Nishida2, A. Tzakis2, H. Ohdan1

    1Hiroshima University, Hiroshima, Japan, 2University of Miami, Miami, FL

    *Purpose: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and is an indication for liver transplantation (LT). Immunosuppressive regimens currently used after…
  • 2021 American Transplant Congress

    Long Term Safety and Efficacy of Tocilizumab (anti-il6r, Tcz) Therapy in the Treatment of Refractory Chronic Antibody Mediated Rejection (cabmr) in 25 Pediatric Renal Transplant Recipients

    M. Pearl1, P. Weng1, A. Dokras2, H. Pizzo3, J. Garrison3, C. Butler1, J. Q. Zhang1, K. Lim3, E. Reed1, I. Kim3, M. Haas3, X. Zhang3, R. Ettenger1, S. Jordan3, D. Puliyanda3

    1Pediatric Nephrology, UCLA Medical Center, Los Angeles, CA, 2Pediatric Nephrology, UT South Western, Dallas, CA, 3Pediatric Nephrology, Cedars Sinai Medical Center, West Hollywood, CA

    *Purpose: Development of de novo donor specific antibodies (DSA) post renal transplantation puts pediatric patients at risk for chronic Antibody Mediated Rejection (cABMR) and allograft…
  • 2021 American Transplant Congress

    Liver Kinase B1 Knockdown Induces Platelet-Derived Growth Factor Receptor B Expression in Human Airway Epithelial Cells: A Potential Mechanism for Development of Fibrosis Leading to Chronic Lung Allograft Dysfunction

    M. Rahman, J. Lee, R. Ravichandran, T. Fleming, M. Smith, R. Bremner, T. Mohanakumar

    St. Joseph’s Hospital and Medical Center, Phoenix, AZ

    *Purpose: The platelet-derived growth factor and its receptor (PDGFRb) signaling pathway can be activated by epithelial mesenchymal transition which facilitates fibrosis. It is not known…
  • 2021 American Transplant Congress

    The Impact of 4-weeks of Supervised Exercise on Frailty and Lower Extremity (LE) Function in Patients with Advanced Chronic Kidney Disease (CKD)

    E. Lorenz, L. Hickson, R. Weatherly, K. Thompson, M. Hogan, C. Kennedy

    Mayo Clinic, Rochester, MN

    *Purpose: Although frailty is a modifiable risk factor for morbidity and mortality among kidney transplant (KT) candidates, the optimal duration of effective prehabilitation interventions is…
  • 2021 American Transplant Congress

    Role of Baseline PD-1 Checkpoint Inhibitor Pathway Expression in Bridge to Liver Transplant Hepatocellular Carcinoma

    K. Nunez, T. Sandow, M. Hibino, A. Cohen, P. Thevenot

    Ochsner Health, New Orleans, LA

    *Purpose: Response to first line liver-directed therapy (LDT) in hepatocellular carcinoma (HCC) has important implications in both bridge to transplant (BTT) success as well as…
  • 2021 American Transplant Congress

    Assessing the Accuracy of the Lung Allocation Score

    N. Dussault1, W. Parker1, R. Jablonski1, E. Garrity1, M. Churpek2

    1University of Chicago, Chicago, IL, 2University of Wisconsin-Madison, Madison, WI

    *Purpose: The Lung Allocation Score (LAS) relies on the performance of two cox proportional hazards models that estimate waitlist and post-transplant survival. These models were…
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