Abstracts Archive - Page 3 of 1683 - ATC Abstracts

2022 American Transplant Congress
Long-Term Kidney Allotransplant Acceptance is Defined by a Shift from a T Cell to a B Cell Rich Immune Microenvironment Within the Graft
E. S. Szuter¹, T. Yokose¹, M. T. Guinn¹, J. Ge², I. Rosales³, B. Kwon⁴, P. S. Russell¹, A. Cuenca², D. Kreisel⁵, P. Sage⁶, J. C. Madsen¹, R. B. Colvin³, A. Alessandrini¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Department of Surgery, Boston Children's Hospital, Boston, MA, ³Department of Pathology, Massachusetts General Hospital, Boston, MA, ⁴Harvard College, Cambridge, MA, ⁵Department of Surgery, Washington University, St. Louis, MO, ⁶Transplantation Research Center, Renal Division, Brigham and Women’s Hospital, Boston, MA
*Purpose: Mouse kidney allografts are spontaneously accepted in select, fully-mismatched donor-recipient strain combinations, such as DBA/2J to C57BL/6 (B6). Tolerant renal grafts develop aggregates of…
2022 American Transplant Congress
Retransplantation in a High-Volume Institution: Historical, Socioeconomic and Survival Trends
D. von Ahrens, O. Sulimani, M. Holzner, M. Akhtar, S. Florman, A. Arvelakis
The Mount Sinai Hospital, New York, NY
*Purpose: Retransplantation for liver allograft failure is a challenge within the field. The evolution of organ allocation policy from Child to MELD in 2002 and…
2022 American Transplant Congress
Long-Term Outcomes of Liver Transplantation (LT) Using Grafts from Donors with Active and Chronic Hepatitis B Virus (HBV) Infection; Multi-Center Cohort Study
S. Suh¹, S. Gang², Y. Choi², S. Hong², N. Yi², K. Lee², K. Suh²
¹Chung-Ang University, Seoul, Korea, Republic of, ²Seoul National University, Seoul, Korea, Republic of
*Purpose: Liver grafts from donors with hepatitis B infection contributed to expand the donor pool under the Hepatitis B immunoglobulin (HBIG) and antiviral agents (NA:…
2022 American Transplant Congress
Deceased Donor Organ Flush with Similar Volumes of HTK and UW at a Single U.S. Organ Procurement Organization: Adult and Pediatric Data
A. E. Mangus¹, C. Kubal², B. Ekser³, P. Mihaylov⁴, A. J. Lutz¹, J. Fridell⁵, R. Mangus⁶
¹Indiana University Purdue University of Indianapolis, Indianapolis, IN, ²Indiana University Hospital, Indianapolis, IN, ³Surgery, Indiana University - Transplant Surgery, Indianapolis, IN, ⁴Indiana Univ School of Medicine, Indianapolis, IN, ⁵Indiana University School of Medicine, Indianapolis, IN, ⁶Indiana University, Indianapolis, IN
*Purpose: Histidine-tryptophan-ketoglutarate (HTK) and University of Wisconsin (UW) solutions are the two primary solid-organ preservation solutions used in the United States (>95%), but flush volumes…
2022 American Transplant Congress
Cold Ischemic Time and Kidney Graft Failure; Mediation Through Delayed Graft Function
J. Miller¹, W. Irish², D. Sawinski³, A. Massie⁴, J. Snyder¹
¹Scientific Registry of Transplant Recipients, Minneapolis, MN, ²Department of Surgery, East Carolina University, Greenville, NC, ³Division of Nephrology and Hypertension, Weill Cornell Medical College, New York, NY, ⁴Division of Surgery, Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: Delayed graft function (DGF) has been associated with decreased graft survival and prolonged cold ischemia time (CIT) has been proposed as a modifiable DGF…
2022 American Transplant Congress
Lucas Device Assisted Uncontrolled Dcd Kidney Transplantation – A Feasible but Underutilized Option in the United States
S. Nagaraju, S. Vaishnav, R. Savilla, M. Moore, J. B. Africa
Renal Transplant, Charleston Area Medical Center, Charleston, WV
*Purpose: Uncontrolled DCD (uDCD) procurement involves either normo-thermic or hypothermic regional perfusion to reduce ischemic injury. We report a series of successful kidney transplant utilizing…
2022 American Transplant Congress
Single Blind Randomized Controlled Trial Comparing BNT162b2 Vs JNJ-78436735 Vaccine As An Additional Dose After Two Doses Of BNT162b2 Vaccine In Solid Organ Transplant (SOT) Recipients
Y. Natori¹, E. Martin², A. Mattiazzi³, J. Bini Viotti¹, K. S. Ortecho⁴, S. Pallikkuth⁵, S. Anjan¹, J. Simkins¹, G. Guerra³
¹Department of Medicine, Division of Infectious Diseases, University of Miami, Miami, FL, ²Department of Medicine, Division of Hepatology, University of Miami, Miami, FL, ³Department of Medicine, Division of Nephrology, University of Miami, Miami, FL, ⁴Miami Transplant Institute, Jackson Health System, Miami, FL, ⁵University of Miami, Miami, FL
*Purpose: Even though a high efficacy and immunogenicity of COVID-19 vaccines have been reported in the general population, vaccine immunogenicity is suboptimal in SOT recipients…
2022 American Transplant Congress
Superoxide in Cardiac Allografts from Donors After Circulatory Death
M. Urban¹, T. Bruett², K. F. Duncan¹, N. W. Markin³, M. M. Chacon³, M. C. Zimmerman⁴
¹Department of Surgery. Division of Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NE, ²College of Medicine. Department of Cellular and Integtrative Physiology., University of Nebraska Medical Center, Omaha, NE, ³Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE, ⁴Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE
*Purpose: Quality of cardiac allografts from donors after circulatory death (DCD) is adversely impacted by warm ischemia and subsequent reperfusion during organ resuscitation. Post-transplant myocardial…
2022 American Transplant Congress
Timing of Hypotension Post Kidney Transplant Impacts the Risk of Subsequent Delayed Graft Function
S. A. Morrison¹, A. Thanamayooran², K. Tennankore¹, A. J. Vinson¹
¹Dalhousie University, Halifax, NS, Canada, ²Nova Scotia Health Authority, Halifax, NS, Canada
*Purpose: Hypotension is common post-kidney transplant and is associated with delayed graft function (DGF; a need for dialysis in the first week post-transplant) and prolonged…
2022 American Transplant Congress
A Randomised Trial Of Normothermic Machine Perfusion Versus Static Cold Storage In Donation After Circulatory Death Renal Transplantation
S. Hosgood¹, C. Callaghan², C. Wilson³, G. Oniscu⁴, B. Phillips⁵, L. Bates³, L. Smith⁶, M. L. Nicholson⁷
¹Surgery, University of Cambridge, Cambridge, United Kingdom, ²Transplant, Guys & St Thomas's, London, United Kingdom, ³Transplant, Freeman Hospital, Newcastle, United Kingdom, ⁴Edinburgh Royal Infirmary, Edinburgh, United Kingdom, ⁵Transplant, Guy's & St Thomas's, London, United Kingdom, ⁶NHSBT, NHSBT, Bristol, United Kingdom, ⁷University of Cambridge, Cambridge, United Kingdom
*Purpose: Kidneys from donation after circulatory death (DCD) donors are more susceptible to cold storage injury and have a high risk of delayed graft function…