Abstracts Archive - Page 295 of 1683 - ATC Abstracts

2021 American Transplant Congress
Acute Dialysis, Mortality and Renal Failure After Heart Alone Transplant by Egfr and Dialysis Requirement in the United States
M. Aljuhani¹, T. Alexy¹, S. Jackson², C. Martin¹, R. Kandaswamy³, S. Riad¹
¹Medicine, University of Minnesota, Minneapolis, MN, ²Complex Care Analytics, Fairview Health Services, Minneapolis, MN, ³Surgery, University of Minnesota, Minneapolis, MN
*Purpose: We examined the early acute dialysis, 90-day mortality and one-year ESRD among OHT recipients by eGFR and dialysis requirement before transplantation.*Methods: Utilizing the SRTR…
2021 American Transplant Congress
Assessing the Impact of Acute Major Adverse Kidney Events on Clinical Outcomes in Heart Transplant Recipients
J. E. Kelly¹, C. Perez¹, D. Taber¹, R. J. Tedford², B. McMahon², S. Alzaidi¹, H. B. Meadows¹
¹Pharmacy, MUSC Health, Charleston, SC, ²Medicine, MUSC Health, Charleston, SC
*Purpose: The purpose of this study was to elucidate contributors to the Major Adverse Kidney Events at 30 days (MAKE-30) outcome in heart transplant recipients…
2021 American Transplant Congress
Effects of Timing of Everolimus Transition on Renal Outcomes in Liver Transplant Recipients
M. Leick¹, H. Belleau², T. McCashland³
¹Nebraska Medicine, Omaha, NE, ²Bryan Health, Lincoln, NE, ³University of Nebraska Medical Center, Omaha, NE
*Purpose: The purpose of this study is to evaluate the effects of the timing of everolimus transition on renal outcomes in liver transplant recipients.*Methods: This…
2021 American Transplant Congress
How Long is the Wait Worthwhile: Cost-Effectiveness of Accepting a Kidney from a Donor with Apolipoprotein L1 High-Risk Genotype
K. Lentine¹, D. Brennan², M. Wang³, M. Schnitzler⁴, H. Xiao⁴, D. Axelrod⁵, J. Snyder⁶, K. Lentine⁴
¹Saint Louis University, St. Louis, MO, ²Johns Hopkins, Baltimore, MD, ³Washington Univ, Saint Louis, MO, ⁴Saint Louis Univ, Saint Louis, MO, ⁵Univ of Iowa, Iowa City, IA, ⁶SRTR, Minneapolis, MN
*Purpose: The Apolipoprotein L1 (APOL1) Long-Term Outcomes (APOLLO) study is underway to define the impact of kidney donor renal risk variants (RRVs) on the survival…
2021 American Transplant Congress
A Novel Liver Assist Device as a Bridge to Liver Transplantation in Acute on Chronic Liver Failure Patients with Multi-Organ Failure
S. Ahmad¹, I. W. Liou¹, J. Reyes², R. Bakthavatsalam³, N. C. Smith⁴, R. L. Carithers¹, C. Martin¹, D. Gao⁵
¹Medicine, University of Washington, Seattle, WA, ²Surgery, University of Washington, SEATTLE, WA, ³Surgery, University of Washington, Seattle, WA, ⁴Nursing, University of Washington, Seattle, WA, ⁵Engineering, University of Washington, Seattle, WA
*Purpose: Acute on chronic liver failure (AOCLF) occurs in nearly 25% of patients with acutely decompensated cirrhosis, with many developing multi-organ failure requiring ventilatory, vasopressor…
2021 American Transplant Congress
Cyp3a5 Extensive Metabolizer Phenotype May be Associated with an Increase in Class 2 Donor Specific Antibodies and Antibody-Mediated Rejection
S. Mirza¹, N. Wilson², J. Van Zyl², P. Nguyen², T. Sam², S. Hall², M. Askar², R. Patel²
¹Texas Tech Univeristy Health Sciences Center Jerry H. Hodge School of Pharmacy, Dallas, TX, ²Baylor University Medical Center at Dallas, Dallas, TX
*Purpose: Tacrolimus (TAC) metabolism is highly dependent on CYP3A5, yet there is limited data on the effect of CYP3A5 genetic polymorphisms in heart transplant recipients…
2021 American Transplant Congress
Evaluate the Effect of Cresemba (isavuconazonium Sulfate) Capsule and Noxafil (posaconazole) Delayed Release Tablets on Tacrolimus Dose to Concentration (D/C) Ratios in Lung Transplant Recipients
H. Sweiss¹, E. Kincaide¹, D. Levine², R. Hall¹
¹University Health, San Antonio, Department of Pharmacotherapy and Pharmacy Services, The University of Texas at Austin, Pharmacotherapy Division, College of Pharmacy, San Antonio, TX, ²University Health, San Antonio, University of Texas Health Science Center at San Antonio, San Antonio, TX
*Purpose: Evaluate the effect of Cresemba (isavuconazonium sulfate) capsule and Noxafil (posaconazole) delayed release tablet on tacrolimus dose to concentration (D/C) ratio in lung transplant.*Methods:…
2021 American Transplant Congress
ABCC2 Haplotypes Associations to Mycophenolic Acid Pharmacokinetics in Stable Renal Transplant Recipients
K. Tornatore¹, D. Brazeau², C. Meaney³, J. Consiglio⁴, A. Gundroo⁵, S. Chang⁶, G. Wilding⁴, L. Cooper³
¹Pharmacy Practice, School of Pharmacy; University at Buffalo- SUNY, Buffalo, NY, ²Pharmacy Practice, Marshall University, Huntington, WV, ³Pharmacy Practice, School of Pharmacy; University at Buffalo, Buffalo, NY, ⁴Biostatistics, School of Public Health; University at Buffalo, Buffalo, NY, ⁵Medicine, School of Medicine; Ohio State University, Columbus, OH, ⁶Medicine, School of Medicine; University at Buffalo, Buffalo, NY
*Purpose: Mycophenolic acid (MPA), exhibits interpatient pharmacokinetic (PK) variability attributed to enterohepatic circulation of the glucuronide metabolite (MPAG) to MPA. This is mediated by multidrug…
2021 American Transplant Congress
Impact of Cypa5 Status on the Clinical and Financial Outcomes of Kidney Transplant
J. Obayemi¹, B. Keating², K. Lentine³, M. Schnitzler³, H. Xiao³, V. Dharnidharka⁴, D. Axelrod⁵
¹Univ of Michigan, Ann Arbor, MI, ²Univ of Pennsylvania, Philadelphia, PA, ³Saint Louis Univ, Saint Louis, MO, ⁴Washington Univ, Seattle, WA, ⁵Univ of Iowa, Iowa City, IA
*Purpose: Pharmacogenetic profiling of transplant recipients has demonstrated marked variation in the metabolism of immunosuppressive medications, particularly tacrolimus. Patients of African ancestry have been found…
2021 American Transplant Congress
Pharmacokinetic Analysis of Direct Acting Antiviral Use on Weight-Adjusted FK506 Trough/dose Ratios in Obese Kidney Transplant Recipients
A. Demirag¹, P. L. Lobo², J. Oberholzer¹, A. Kumar², B. Rawashdeh¹, S. L. Lennon¹, H. N. Guvener Demirag¹, A. Doyle², J. Geystone³, K. L. Brayman¹
¹Transplantation, University of Virginia Medical Center, Charlottesville, VA, ²Transplantation Nephrology, University of Virginia Medical Center, Charlottesville, VA, ³Clinical Pharmacy, University of Virginia Medical Center, Charlottesville, VA
*Purpose: Using hepatitis C viremic (HCV) organs in kidney transplant recipients(KTRs) is very important to decrease the number of patients on the waiting list. Direct…