ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    An Immune-Modulatory Strategy to Mitigate Hepatic Ischemia Reperfusion Injury in a Murine Model

    S. Duarte, A. Kobayashi, V. Boominathan, A. Kwiatkowski, J. Simonovich, A. Wanchoo, G. Hudalla, B. Keselowsky, A. Zarrinpar

    University of Florida, Gainesville, FL

    *Purpose: Hepatic ischemia/reperfusion injury (IRI) is the leading cause of early graft dysfunction and contributes to the shortage of donor liver grafts. However, despite its…
  • 2022 American Transplant Congress

    Transition Program for Young Adults with Solid Organ Transplant a Single Center Protocol

    H. Y. Lee

    Program for Pediatric Cardiomyopathy, Heart Failure, and Cardiac Transplantation, Columbia University Irving Medical Center, New York, NY

    *Purpose: The transition process for young adult solid organ transplant patient is an important clinical milestone in a transplant patient's life. Evidenced based research demonstrates…
  • 2022 American Transplant Congress

    Single Center Experience with Acute Kidney Injury Deceased Donor Kidneys from Marginal Donors

    B. K. Sharda, M. Garner, A. Farney, G. Orlando, C. Jay, J. Rogers, A. Daniel, A. Gutierrez, N. Sakhovskaya, R. Stratta

    Atrium Health Wake Forest Baptist Medical Center, Winston Salem, NC

    *Purpose: Many centers will selectively transplant kidneys from standard criteria donors (SCD) with terminal acute kidney injury (AKI). However, there is limited experience with transplanting…
  • 2022 American Transplant Congress

    The Impact of Early Graft Infiltrating TCF-1LowPD-1HighCD8+ T Cells in Delayed Fc Nonbinding Anti-CD3 Antibody Protocol in the Sensitized Mouse Model

    T. Ota1, R. Goto1, T. Harada1, Y. Ganchiku1, M. Zaitsu1, A. Forgioni1, N. Kawamura2, M. Watanabe2, M. Fukai1, T. Shimamura3, A. Taketomi1

    1Dept. of Gastroenterological Surgery I, Hokkaido University, Sapporo, Japan, 2Dept. of Transplant Surgery, Hokkaido University, Sapporo, Japan, 3Division of Organ Transplantation, Hokkaido University Hospital, Sapporo, Japan

    *Purpose: Fc nonbinding anti(a)-CD3 antibody has a unique effect that delayed treatment protocol induces a transplant tolerance. Delayed protocol allows early graft infiltrating cells which…
  • 2022 American Transplant Congress

    Impact of Kidney Allocation Change on Low Volume Kidney Transplant Centers

    S. Nagaraju1, S. Vaishnav1, S. A. Deslich2, S. Hanna1, A. Jones3, J. B. Africa1

    1Renal Transplant, Charleston Area Medical Center, Charleston, WV, 2Research Associate Senior, Health Services & Outcomes Rsc, Charleston Area Medical Center, Charleston, WV, 3Charleston Area Medical Center, Charleston, WV

    *Purpose: Effective March 15, 2021, the OPTN launched a new policy for matching kidney and pancreas transplant candidates with organs from deceased donors. The new…
  • 2022 American Transplant Congress

    Deletion of AIF-1 Promotes Kidney Reparative Macrophages and Prevents Fibrosis

    I. Husain, A. Dangi, X. Luo

    Duke University School of Medicine, Durham, NC

    *Purpose: A major etiology contributing to poor allograft survival is the inevitable ischemic insult it incurs during transplantation. Macrophages are key players in ischemia-reperfusion injury,…
  • 2022 American Transplant Congress

    Graft and Patient Outcomes of Kidney Transplant Tourism: A Single-Center Experience

    A. Altheaby1, R. Algain2, R. Salem2, A. Alotaibi2, K. Owaidah2, M. Tawahri1, M. Shaheen3, Z. Arabi4

    1Nephrology, King Abdulaziz Medical City-NGHA, Riyadh, Saudi Arabia, 2Internal Medicine, King Abdulaziz Medical City-NGHA, Riyadh, Saudi Arabia, 3King Saud Bin Abdulaziz for Health Sciences, Riyadh, Saudi Arabia, 4Renal Transplant, King Abdulaziz Medical City-NGHA, Riyadh, Saudi Arabia

    *Purpose: The expanding supply-demand mismatch between organs available for transplantation and patients in need led to the growth of transplant tourism. In our study, we…
  • 2022 American Transplant Congress

    Clinical Features and Outcomes of Hospitalized Solid Organ Transplant and Hematopoietic Stem Cell Recipients with Sars-CoV-2 Infection in the Midwestern United States: A Multi-Center Retrospective Cohort Study

    S. Tanna1, D. Florescu2, A. Majeed3, J. Banzon3, S. Waller4, A. Eid4, N. Barros Baertl5, D. Friedman6, K. Mullane7, M. Ison8

    1Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL, 2University of Nebraska Medical Center, Omaha, NE, 3Cleveland Clinic, Cleveland, OH, 4University of Kansas Medical Center, Overland Park, KS, 5Infectious Diseases, Indiana University, Indianapolis, IN, 6Infectious Diseases, University of Chicago, Chicago, IL, 7University of Chicago, Chicago, IL, 8Northwestern University Comprehensive Transplant Center, Chicago, IL

    *Purpose: Immunocompromised hosts are at risk for severe complications or death from SARS-CoV-2 infection. Few studies describe the clinical features, outcomes and treatment strategies in…
  • 2022 American Transplant Congress

    Eliminating Hepatitis C Positive Status from Kidney Donor Profile Index (KDPI) Calculations Results in Improved Transplant Rates and Outcomes in an Elderly Veteran Population

    R. Lopez-Soler1, A. Thorndyke1, C. Trotter1, A. Abadier2, M. Samra1

    1Surgery, Transplantation, Edward Hines Jr. Veterans Administration Hospital, Hines, IL, 2Surgery, Loyola University Medical School, Maywood, IL

    *Purpose: Overall mortality on the kidney transplant waiting list is higher for older patients. The average age of waitlisted veteran patients is 64, with patients…
  • 2022 American Transplant Congress

    Functional Recellularized Patient Derived Endothelium; A Human Vascular Graft Approach

    H. Tejeda Mora1, J. Willemse2, Y. den Hartog1, I. Schurink2, M. M. Verstegen2, J. de Jonge2, R. C. Minnee2, M. W. van den Hoogen2, C. C. Baan1, L. J. van der Laan2, M. J. Hoogduijn1

    1Transplant Institute - Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands, 2Transplant Institute - Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands

    *Purpose: In transplantation, the endothelial lining is the first barrier between the donor organ and recipient immune system. Damaged endothelium exposes extracellular matrix (ECM) molecules…
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