ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    T-cell-Mediated Immunity to Sars-cov-2 Defines Covid-19 Risk and Severity in Transplanted and Non-Transplanted Individuals and Associates with Myeloid-Derived Suppressor Cells

    C. Ashokkumar1, V. Rohan2, A. H. Kroemer3, S. Rao4, G. Mazariegos5, B. W. Higgs5, S. Nadig2, M. Ningappa5, T. Fishbein3, S. Subramaniam6, R. Sindhi7

    1Plexision, Pittsburgh, PA, 2Medical University of South Carolina, Charleston, SC, 3MedStar Georgetown Transplant Institute, Georgetown, DC, 4DHR Health Institute for Research and Development, Texas, TX, 5University of Pittsburgh, Pittsburgh, PA, 6University of California, San Diego, CA, 7University of Pittsburgh, pittsburgh, PA

    *Purpose: We assessed whether COVID-19-risk is enhanced by chronic immunosuppression, and is associated with suppressor cells.*Methods: We tested 66 COVID-19 patients, including 26 with solid…
  • 2021 American Transplant Congress

    Combined CD11b/CD40 Blockade is Superior to CD40 Blockade Alone in Prolonging Survival in Pig-to-Nonhuman Primate Renal Xenotransplantation

    D. A. Faber1, B. Lovasik1, A. Matar1, C. Breeden1, S. Kim1, A. Adams2

    1Surgery, Emory University School of Medicine, Atlanta, GA, 2Surgery, University of Minnesota, Minneapolis, MN

    *Purpose: Blockade of the CD40/CD154 pathway is highly effective in preventing rejection in pig-to-nonhuman primate (NHP) xenotransplantation models. Clinical translation of anti-CD154 mAbs, however, has…
  • 2021 American Transplant Congress

    Death Among Living Liver Donors- Are We Overestimating the Risk?

    H. J. Braun, A. M. Shui, N. L. Ascher, J. P. Roberts

    University of California, San Francisco, San Francisco, CA

    *Purpose: In the United States, the estimated risk of death associated with live liver donation is currently quoted at 0.1% for left lobe donation, and…
  • 2021 American Transplant Congress

    Allograft Discard Risk Index for Heart Transplantation

    R. M. Reul1, A. A. Saleem1, C. N. Keller1, T. H. Malik1, J. A. Goss2, A. A. Rana2

    1Office of Student Affairs, Baylor College of Medicine, Houston, TX, 2Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX

    *Purpose: The number of patients awaiting heart transplantation (HTx) substantially exceeds the number of donor hearts transplanted each year, yet nearly 70% of consented donor…
  • 2021 American Transplant Congress

    Simultaneous Pancreas-kidney Transplantation (spk) and, Simultaneous Deceased Donor Pancreas and Living Donor Kidney Transplantation (splk) in Diabetic Patients with End Stage Renal Disease

    Y. Ko

    Department of Surgery, Asan Medical Center, Seoul, Korea, Republic of

    *Purpose: The purpose of this study is to compare clinical outcomes of simultaneous pancreas-kidney transplantation (SPK) and simultaneous deceased donor pancreas and living donor kidney…
  • 2021 American Transplant Congress

    Liver Biopsy as a Predictor in Risk Stratification for Heart Transplant Candidates

    S. Tolia1, T. Al Saadi1, N. Narang2, A. Joshi2, C. Sciamanna2, S. Pauwaa2, G. Macaluso2, M. Dia2, A. Tatooles3, P. Pappas3, W. Cotts2, A. Andrade2

    1Internal Medicine, Advocate Christ Medical Center, Oak Lawn, IL, 2Cardiology, Advocate Christ Medical Center, Oak Lawn, IL, 3Cardiovascular Surgery, Advocate Christ Medical Center, Oak Lawn, IL

    *Purpose: Patients undergoing workup for Orthotopic Heart Transplant (OHT) undergo multi-organ evaluation for risk stratification. While cirrhosis is a known predictor of poor outcomes in…
  • 2021 American Transplant Congress

    Evaluation and Experience with Hepatitis C Positive to Negative PancreasTransplantation

    B. K. Lindner, B. Thomas, M. Cooper, S. Yi, P. Abrams

    Medstar Georgetown University Hospital, Washington, DC

    *Purpose: The use of hepatitis C virus (HCV) positive organs for transplant to HCV negative recipients has been reported on and has gained popularity across…
  • 2021 American Transplant Congress

    Waitlist and Post-Transplant Outcomes of Candidates with Iabp or Ecmo: Comparison of Old and New Heart Allocation Policies

    M. Colvin1, Y. Ahn2, S. Hall3, M. Skeans2, M. Walsh4, A. Israni2

    1Univ of Michigan, Ann Arbor, MI, 2SRTR, Minneapolis, MN, 3Baylor Univ, Dallas, TX, 4St. Vincent Heart Ctr, Indianapolis, IN

    *Purpose: New heart allocation policy prioritizes candidates on short-term circulatory support to promote transplant of the sickest candidates. There has been a shift in the…
  • 2021 American Transplant Congress

    Segmental Susceptibility of Intestinal Stem Cells to Cold Storage Preservation Injury in a Porcine Model

    E. K. Ludwig1, N. Abraham2, D. Sudan2, A. Barbas2, C. Schaaf1, J. Freund1, A. S. Stewart1, B. Veerasammy1, L. M. Gonzalez1

    1North Carolina State University, Raleigh, NC, 2Duke University, Durham, NC

    *Purpose: Cold storage (CS) is the current gold standard preservation method for small bowel (SB) prior to transplantation. However, CS can cause epithelial detachment, sloughing,…
  • 2021 American Transplant Congress

    Waitlist and Post-Transplant Outcomes of Candidates With Lvad: Comparison of Old and New Heart Allocation Policies

    M. Colvin1, Y. Ahn2, S. Hall3, M. Walsh4, A. Israni2

    1Univ of Michigan, Ann Arbor, MI, 2SRTR, Minneapolis, MN, 3Baylor Univ, Dallas, TX, 4St. Vincent Heart Ctr, Indianapolis, IN

    *Purpose: The new heart allocation policy took effect in October 2018. Its risk stratification scheme prioritizes patients with short-term devices, raising concern that candidates with…
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