ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Association Between CT Measurements of Body Composition Before Liver Transplantation and Post-Transplantation Outcomes

    Y. Liu1, O. Shafaat1, K. Jackson1, J. Motter1, B. Boyarsky1, M. Latif1, F. Yuan1, E. King1, A. Zaheer1, R. Summers2, D. Segev1, M. McAdams-DeMarco1, C. Weiss1

    1Johns Hopkins University, Baltimore, MD, 2NIH Clinical Center, Bethesda, MD

    *Purpose: Various methods exist for measuring body composition using computed tomography (CT) scans; however, it is unclear which components best predict post-liver transplantation (LT) outcomes.…
  • 2022 American Transplant Congress

    Mortality and Cardiovascular Outcomes in Adult Non-Liver Solid Organ Transplant Patients with Non-Alcoholic Steatohepatitis

    N. Dutta1, N. Marka2, J. Lake1, N. Lim1

    1Medicine, University of Minnesota, Minneapolis, MN, 2Clinical and Translational Sciences Institute, University of Minnesota, Minneapolis, MN

    *Purpose: Despite the increasing incidence of non-alcoholic steatohepatitis (NASH) worldwide, its impact on mortality or major adverse cardiovascular events (MACE) in non-liver solid organ transplant…
  • 2022 American Transplant Congress

    Bone Fractures Are Not Increased in Older Prior Living Kidney Donors

    H. Amer1, H. Maradit Kremers1, D. Larson1, I. Zaniletti1, W. K. Kremers1, A. Matas2, B. Kasiske3, S. Khosla1, R. Kumar1

    1Mayo Clinic, Rochester, MN, 2University of Minnesota, Minneapolis, MN, 3Hennepin County Medical Center, Minneapolis, MN

    *Purpose: Living kidney donors were shown to have derangements of bone biomarkers resembling those occurring in early chronic kidney disease within 36 months of donation.…
  • 2022 American Transplant Congress

    Risk Factors Associated with ICU Admission and Death in Patients Hospitalized with COVID-19 Differ Between Solid Organ Transplant and Non-Solid Organ Transplant Patients

    J. Schaenman, H. Byford, T. R. Grogan, Y. Motwani, O. Beaird, M. Kamath, E. Lum, K. Meneses, D. Sayah, D. Vucicevic, S. Saab

    David Geffen School of Medicine at UCLA, Los Angeles, CA

    *Purpose: Despite the large numbers of reports on patient risk factors for poor clinical outcomes with COVID-19, little is known about how these risks may…
  • 2022 American Transplant Congress

    Leveraging Single-Cell Signatures in Kidney Transplant Biopsies Uncovers Immunological Heterogeneity Within Rejection Phenotypes

    J. Callemeyn1, B. Lamarthée1, P. Koshy2, T. Debyser3, E. Van Loon1, A. Franken4, T. Van Brussel4, I. Arijs4, D. Lambrechts4, M. Rabant5, A. Senev1, T. Vaulet6, C. Tinel1, M. Naesens1

    1Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, 2Department of Morphology and Molecular Pathology, University Hospitals Leuven, Leuven, Belgium, 3Faculty of Medicine, KU Leuven, Leuven, Belgium, 4Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium, 5Necker-Enfants Malades Institute, Institut national de la santé et de la recherche médicale (Inserm), Université de Paris, Paris, France, 6ESAT Stadius Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium

    *Purpose: Rejection of the kidney allograft is hallmarked by the accumulation of inflammatory cells within the renal architecture, leading to microvascular or tubulointerstitial inflammation. However,…
  • 2022 American Transplant Congress

    Center Variation is the Major Driver of Geographic Disparities in Access to Kidney Transplants Among Waitlisted Candidates

    D. Stewart, A. Robinson, A. Wilk, D. Klassen

    United Network for Organ Sharing, Richmond, VA

    *Purpose: The OPTN’s monitoring of equity in access to deceased donor kidney (KI) transplants (tx) among waitlisted candidates has consistently found service area (DSA) of…
  • 2022 American Transplant Congress

    Treatment Modality and Outcomes of Antibody-Mediated Rejection in Pediatric Kidney Transplant Recipients: The PARAMOUr Study

    R. Engen1, A. Jain2, N. Hayde3, A. Mansuri4, M. Kallash5, S. McEwen6, R. Garro7, C. Peterson8, R. Zahr9, L. Harshman10, D. Puliyanda11, S. Solomon12, K. Twombley13, I. Ashoor14

    1Pediatrics, University of Wisconsin Madison, Madison, WI, 2Wayne State University, Detroit, MI, 3Albert Einstein College of Medicine, New York, NY, 4Augusta University, Augusta, GA, 5The Ohio State University, Columbus, OH, 6University of Minnesota, Minneapolis, MN, 7Emory University, Atlanta, GA, 8University of Utah Health, Salt Lake City, UT, 9The University of Tennessee Health Science Center, Memphis, TN, 10University of Iowa, Iowa City, IA, 11Cedars-Sinai Medical Center, Los Angeles, CA, 12New York Medical College, Valhalla, NY, 13Medical University of South Carolina, Charleston, SC, 14Louisiana State University, New Orleans, LA

    *Purpose: Antibody-mediated rejection (AMR) is the leading cause of graft failure in kidney transplantation, but evidence for effective treatments is limited.*Methods: PARAMOUr is a retrospective…
  • 2022 American Transplant Congress

    Bionic Pancreas – The First Results of Functionality of 3D-Bioprinted Bionic Tissue Model Transplantation with Pancreatic Islets

    M. Klak1, M. Wszola1, A. Berman1, A. Filip1, A. Kosowska2, J. Olkowska-Truchanowicz2, G. Tymicki1, M. Rachalewski1, T. Bryniarski1, M. Kolodziejska1, T. Dobrzanski3, D. Ujazdowska1, J. Wejman4, I. Uhrynowska-Tyszkiewicz2, A. Kaminski2

    1Foundation of Research and Science Development, Warsaw, Poland, 2Medical University of Warsaw, Warsaw, Poland, 3Polbionica Ltd., Warsaw, Poland, 4Center for Pathomorphological Diagnostics Ltd, Warsaw, Poland

    *Purpose: Tissue engineering is currently on advanced stage of development which gives a possibilities for novel strategy of personal treatment of type 1 diabetes. AIM:…
  • 2022 American Transplant Congress

    The Effect of Baseline Blood Pressure on Early Graft Function in Deceased Donor Kidney Transplantation

    B. Jun Bae1, C. Oh1, H. Ahn2

    1Department of surgery, Ajou University Medical School, Suwon, Korea, Republic of, 2Department of Anesthesiology and Pain medicine, Ajou University Medical School, Suwon, Korea, Republic of

    *Purpose: The adequate perfusion pressure to the graft is essential for proper graft function in kidney transplantation, especially in deceased donor kidney transplantation. Therefore, the…
  • 2022 American Transplant Congress

    Sars-cov-2 Antibody and T Cell Response After Vaccination with or without Intensified Immunosuppression Among Pediatric Renal Transplant Recipients

    H. Pizzo1, B. Shin2, P. R. Soni3, S. Nadipuram3, J. Garrison2, R. Zhang2, S. C. Jordan2, D. Puliyanda1

    1Pediatric Nephrology, Cedars-Sinai Medical Center, Los Angeles, CA, 2Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, 3Pediatric Infectious Disease, Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: Recent data has shown poor antibody response to SARS-CoV-2 vaccination among adult kidney transplant (tx) recipients, with seroconversion ranging between 22%-58% after two mRNA…
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