ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Impact of Traveling for Transplant on Access to and Outcomes from Kidney and Liver Transplantation

    K. Ross-Driscoll1, R. Lynch1, D. Axelrod2, R. Patzer1

    1Emory University, Atlanta, GA, 2University of Iowa, Ames, IA

    *Purpose: Newly developed transplant referral regions (TRRs) can be used to understand how and why patients travel outside of their home transplant center to receive…
  • 2021 American Transplant Congress

    Kidney Transplantation in Times of Covid-19 – Decision Analysis in the Canadian Context

    I. Yanev1, M. Gagnon1, M. Cheng2, S. Paraskevas2, D. Kumar3, A. Dragomir4, R. Sapir-Pichhadze4

    1McGill University, Montreal, QC, Canada, 2McGill University Health Centre, Montreal, QC, Canada, 3University Health Network, Toronto, ON, Canada, 4Research Institute of McGill University Health Centre, Montreal, QC, Canada

    *Purpose: The coronavirus disease 2019 (COVID-19) pandemic significantly impacted the field of transplantation across Canada. In this study, we outline the implications of COVID-19 related…
  • 2021 American Transplant Congress

    Elevated Tacrolimus Levels in Hospitalized Organ Transplant Recipients with COVID-19

    K. Mecadon1, A. Hardesty2, K. Vieira3, R. Rogers3, B. Merhi4, A. J. Osband5, G. Bayliss4, R. Gohh4, P. Morrissey5, D. Farmakiotis3

    1Department of Pharmacy, Rhode Island Hospital, Providence, RI, 2Department of Internal Medicine, Residency, Warren Alpert Medical School of Brown University, Providence, RI, 3Division of Infectious Diseases, Warren Alpert Medical School of Brown University, Providence, RI, 4Division of Nephrology, Warren Alpert Medical School of Brown University, Providence, RI, 5Department of Surgery (Transplantation), Warren Alpert Medical School of Brown University, Providence, RI

    *Purpose: The effect of COVID-19 on immunosuppressant drug levels in organ transplant recipients (OTRs) has not been adequately studied.*Methods: We retrospectively studied hospitalized adult (>18-year-old)…
  • 2021 American Transplant Congress

    Quantification of Multiple Isotypes of Anti-SARS-CoV-2 Antibodies in Kidney Transplant Recipients

    J. S. Maltzman1, L. Wang1, P. Ahearn1, T. Yalamarti1, M. Menon2, Y. Azzi3, M. Melcher1, M. Fernandez-Vina1, R. Bray4, H. Gebel4, E. Woodle5, E. Akalin3, A. Girnita1, P. Cravedi2

    1Stanford University, Palo Alto, CA, 2Icahn School of Medicine, NYC, NY, 3Einstein School of Medicine, NYC, NY, 4Emory University, Atlanta, GA, 5University of Cincinnati, Cincinnati, OH

    *Purpose: Solid organ transplant recipients are at increased risk of severe outcomes with infection by SARS-CoV-2, the etiologic agent of COVID-19. Antibodies directed against the…
  • 2021 American Transplant Congress

    Monoclonal Antibodies for Covid-19 in Patients with Solid Organ Transplant Recipients

    L. Hasan1, H. Hardgrave2, T. Osborn3, R. Dare1, L. Burdine4, E. Giorgakis4, J. Rico1

    1Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 2University of Arkansas for Medical Sciences, Little Rock, AR, 3Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, 4Transplant surgery, University of Arkansas for Medical Sciences, Little Rock, AR

    *Purpose: The FDA has issued Emergency Use Authorization (EUA) for monoclonal antibodies for the treatment of mild to moderate COVID-19 in patients at risk for…
  • 2021 American Transplant Congress

    Comparison of Outcomes of Living Donor Liver Transplantation for Biliary Atresia Patients with and without Kasai Portoenterostomy

    T. Kanmaz1, O. Andacoglu1, Y. Yankol2, C. Karatas1, N. Mecit1, K. Acarli3, M. Kalayoglu1

    1Koc University, Istanbul, Turkey, 2University of Wisconsin, Madison, WI, 3Memorial Hospital, Istanbul, Turkey

    *Purpose: We evaluated 10 year outcomes and the potential predictors of outcomes after living donor liver transplant (LT) for biliary atresia (BA) patients with and…
  • 2021 American Transplant Congress

    Hepatoportoenterostomy versus Primary Liver Transplantation for Biliary Atresia: A Review of the National Experience

    D. Yoeli1, R. A. Choudhury1, S. S. Sundaram2, C. L. Mack2, J. P. Roach3, F. M. Karrer4, M. E. Wachs1, M. A. Adams1

    1Transplant Surgery, University of Colorado and Children's Hospital Colorado, Aurora, CO, 2Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado and Children's Hospital Colorado, Aurora, CO, 3Pediatric Surgery, University of Colorado, Aurora, CO, 4Pediatric Surgery, University of Colorado and Children's Hospital Colorado, Aurora, CO

    *Purpose: Kasai hepatoportoenterostomy (HPE) followed by liver transplantation (LT) if needed is the standard of care for children with biliary atresia (BA). Some, however, have…
  • 2021 American Transplant Congress

    Evaluation of Safety and Efficacy of PCSK9 Inhibitors in Solid Organ Transplant Recipients: Experience at a Large Multi-organ Transplant Center

    A. Ucci1, M. Norris2, J. Trofe-Clark2, T. Fallah2, M. Meck1, R. Samudralwar1, M. V. Genuardi3

    1Hospital of Univ of Pennsylvania, Philadelphia, PA, 2Penn Transplant Institute, Hospital of Univ of Pennsylvania, Philadelphia, PA, 3Cardiovascular Medicine Div, Hospital of Univ of Pennsylvania, Philadelphia, PA

    *Purpose: The aim of the study was to characterize the efficacy and safety of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in solid organ transplant…
  • 2021 American Transplant Congress

    Postoperative Tracheostomy as a Predictor of Poor Clinical Outcomes in Lung Transplantation

    E. C. Klipsch, T. J. Hathaway, D. Roe, C. Hage, M. Duncan, R. S. Mangus

    Indiana University School of Medicine, Indianapolis, IN

    *Purpose: Tracheostomies are commonly performed postoperatively in lung transplant recipients to provide ventilation for prolonged periods, and with relatively few studies detailing these patients’ outcomes…
  • 2021 American Transplant Congress

    The Impact of Tacrolimus IPV and TTR on the Development of De Novo Donor-specific Antibodies in Kidney Transplant Recipients

    D. Xu1, K. Richards1, K. Zheng1, H. Patel2, F. Cardarelli2, J. A. Pena3, A. Aala2

    1Pharmacy, Beth Israel Deaconess Medical Center, Boston, MA, 2Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, 3Pathology, Beth Israel Deaconess Medical Center, Boston, MA

    *Purpose: High intrapatient variability (IPV) and low time in therapeutic range (TTR) of tacrolimus (TAC) may increase the risk of developing de novo donor-specific antibodies…
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