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American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Covid-19 Infections Post-liver and Kidney Transplantation in a Southern Ca Program

    M. E. de Vera1, J. Woloszyn2, S. Regmi2, R. Rattanavich2, M. Rakoski2, M. Lin2, P. Mehta2, A. Kore2, J. Weissman2, C. Martens2, T. Phan2, B. Jerez-Aguilar2, M. Robinson2, E. Wells2, R. Villicana2, M. Nguyen2

    1Loma Linda University Health, San Bernardino, CA, 2Transplant Institute, Loma Linda University Health, San Bernardino, CA

    *Purpose: Southern CA is at the epicenter of the Covid-19 pandemic. We reviewed outcomes of our center's liver, kidney, and pancreas transplant patients stricken with…
  • 2021 American Transplant Congress

    Letermovir Prophylaxis in Solid Organ Transplant – CMV Breakthrough and Tacrolimus Drug Interaction

    R. Winstead1, D. Kumar1, A. Brown1, I. Yakubu1, C. Song1, L. Thacker2, G. Gupta1

    1Virginia Commonwealth University Health, Richmond, VA, 2Virginia Commonwealth University, Richmond, VA

    *Purpose: Valganciclovir is the preferred drug for cytomegalovirus (CMV) prophylaxis in solid organ transplantation. A limitation to its use is profound myelosuppression. Letermovir is a…
  • 2021 American Transplant Congress

    The Calculated Panel of Incompatible Epitopes (cPIE) in the Service of Equitable Access to Transplantation

    J. Lamsatfi1, B. Bingfan Liu1, S. Parto2, A. Lewin3, K. Oualkacha1, F. Claas4, P. Keown5, R. Sapir-Pichhadze6

    1McGill University, Montreal, QC, Canada, 2McGill University Health Centre, Montreal, QC, Canada, 3Hema-Quebec, Montreal, QC, Canada, 4Leiden University Medical Centre, Albinusdreef, Netherlands, 5University of British Columbia, Vancouver, BC, Canada, 6Medicine, McGill University Health Centre, Montreal, QC, Canada

    *Purpose: To inform on feasibility of eplet matching, we developed the calculated Panel of Incompatible Epitopes (cPIE), an algorithm informing on the likelihood of identifying…
  • 2021 American Transplant Congress

    Distal Allograft Pancreatectomy for Graft Salvage After Pancreas Transplantation

    D. Soma, T. Nikumbh, A. J. Lutz, J. A. Powelson, J. A. Fridell

    Transplant Division, Department of Surgery, Indiana University School of Medicine, Indianapolis, IN

    *Purpose: Early pancreas allograft failure most commonly results from vascular thrombosis. Immediate surgical intervention may permit pancreas allograft salvage, typically requiring thrombectomy. In cases of…
  • 2021 American Transplant Congress

    Kidney Transplantation in Times of Covid-19 – Decision Analysis in the Canadian Context

    I. Yanev1, M. Gagnon1, M. Cheng2, S. Paraskevas2, D. Kumar3, A. Dragomir4, R. Sapir-Pichhadze4

    1McGill University, Montreal, QC, Canada, 2McGill University Health Centre, Montreal, QC, Canada, 3University Health Network, Toronto, ON, Canada, 4Research Institute of McGill University Health Centre, Montreal, QC, Canada

    *Purpose: The coronavirus disease 2019 (COVID-19) pandemic significantly impacted the field of transplantation across Canada. In this study, we outline the implications of COVID-19 related…
  • 2021 American Transplant Congress

    Donor-specific Anti-HLA Alloantibody in Kidney Transplant Recipients with COVID-19 Exhibit a Different Immunoglobulin Class and Subclass Profile When Compared to Anti-SARS-CoV-2 Antibodies

    A. Girnita1, L. Wang1, M. Fernandez-Vina1, E. Woodle2, P. Ahearn1, T. Yalamarti1, M. Menon3, Y. Azzi4, M. Melcher1, R. Bray5, H. Gebel5, E. Akalin4, P. Cravedi3, J. S. Maltzman1

    1Stanford University, Palo Alto, CA, 2University of Cincinnati, Cincinnati, OH, 3Icahn School of Medicine, NYC, NY, 4Einstein School of Medicine, NYC, NY, 5Emory University, Atlanta, GA

    *Purpose: Both anti-HLA and anti-SARS-CoV-2 antibodies target protein antigens. The aim of the present study was to compare the class and subclass profile of such…
  • 2021 American Transplant Congress

    Impact of Traveling for Transplant on Access to and Outcomes from Kidney and Liver Transplantation

    K. Ross-Driscoll1, R. Lynch1, D. Axelrod2, R. Patzer1

    1Emory University, Atlanta, GA, 2University of Iowa, Ames, IA

    *Purpose: Newly developed transplant referral regions (TRRs) can be used to understand how and why patients travel outside of their home transplant center to receive…
  • 2021 American Transplant Congress

    Panic in the Pandemic: A Medical Decision Analysis Examining When Kidney Transplant Programs Should Close

    A. J. Vinson1, B. Kiberd2, K. Tennankore1

    1Nova Scotia Health Authority Division of Nephrology, Departm, Halifax, NS, Canada, 2Dalhousie University, Halifax, NS, Canada

    *Purpose: Pandemics greatly interfere with overall health care delivery as resources are diverted to combat the crisis. Kidney transplantation programs were closed temporarily during the…
  • 2021 American Transplant Congress

    Unclear Implications of Tacrolimus Time in Therapeutic Range as a Predictor of Acute Rejection in Renal Transplant Recipients Undergoing Early Corticosteroid Withdrawal

    D. Pierce, P. West-Thielke, Z. Hajjiri, S. Gaitonde, I. Tzvetanov, E. Benedetti, A. Lichvar

    University of Illinois at Chicago, Chicago, IL

    *Purpose: Tacrolimus (TAC) demonstrates a wide intra- and inter-patient variability (IPV) necessitating therapeutic drug monitoring. The purpose of this study is to determine the impact…
  • 2021 American Transplant Congress

    Early Review of Liver Acuity Circles Allocation

    S. Noreen1, J. Heimbach2, J. Pomposelli3, M. Cafarella1, J. Trotter4

    1UNOS, Richmond, VA, 2Mayo Clinic, Rochester, MN, 3UCHealth, Aurora, CO, 4BSWHealth, Dallas, TX

    *Purpose: Acuity circles (AC) allocation was implemented on February 4, 2020, followed shortly by the declaration of national emergency for COVID-19. The goal of this…
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