2021 American Transplant Congress
Accounting for Survivor Bias in Transplant Benefit Models
*Purpose: The lung allocation system in the U.S. prioritizes lung transplant candidates based on estimated pre- and post-transplant survival. However, these models do not account…2021 American Transplant Congress
Covid-19 Infections Post-liver and Kidney Transplantation in a Southern Ca Program
*Purpose: Southern CA is at the epicenter of the Covid-19 pandemic. We reviewed outcomes of our center's liver, kidney, and pancreas transplant patients stricken with…2021 American Transplant Congress
Corticosteroid Reintroduction in Urban Simultaneous Kidney-pancreas Transplant Recipients Following an Early Corticosteroid Withdrawal Protocol
University of Illinois at Chicago, Chicago, IL
*Purpose: Approximately 30% of patients who undergo simultaneous kidney-pancreas (SKP) transplant are maintained on dual therapy with tacrolimus and mycophenolate. Long-term implications of steroid reintroduction…2021 American Transplant Congress
Assessing the Impact of the New Liver Allocation Policy on Transplant Center and Organ Procurement Organization Logistics
*Purpose: In February 2020, a new policy for liver allocation was instituted in an effort to reduce geographic disparity in median MELD at transplant. To…2021 American Transplant Congress
Enteric Conversion After Bladder-drained Kidney-pancreas Transplantation
*Purpose: In simultaneous kidney-pancreas transplantation (SPK), bladder (BD) and enteric (ED) are both options for pancreaticoduodenal exocrine drainage. While BD provides good early and long…2021 American Transplant Congress
Letermovir Prophylaxis in Solid Organ Transplant – CMV Breakthrough and Tacrolimus Drug Interaction
*Purpose: Valganciclovir is the preferred drug for cytomegalovirus (CMV) prophylaxis in solid organ transplantation. A limitation to its use is profound myelosuppression. Letermovir is a…2021 American Transplant Congress
High Levels of Sars-cov-2 Detected in Immunosuppressed Covid-19 Patient Environments Weeks Following Initial Positive Test
*Purpose: COVID-19 is a novel viral illness associated with significantly worse mortality, prolonged disease course, and extended periods of viral shedding in transplant patients on…2021 American Transplant Congress
Human Leukocyte Antigen Mismatches Between Donor-Recipient or Donor-Donor are Not Associated with Adverse Pancreas Outcomes in Pancreas After Kidney Transplant Recipients
University of Wisconsin, MADISON, WI
*Purpose: A greater degree of HLA mismatch has been previously associated with inferior graft survival in kidney and pancreas transplantation. Pancreas after kidney (PAK) recipients…2021 American Transplant Congress
Unclear Implications of Tacrolimus Time in Therapeutic Range as a Predictor of Acute Rejection in Renal Transplant Recipients Undergoing Early Corticosteroid Withdrawal
University of Illinois at Chicago, Chicago, IL
*Purpose: Tacrolimus (TAC) demonstrates a wide intra- and inter-patient variability (IPV) necessitating therapeutic drug monitoring. The purpose of this study is to determine the impact…2021 American Transplant Congress
Donor-specific Anti-HLA Alloantibody in Kidney Transplant Recipients with COVID-19 Exhibit a Different Immunoglobulin Class and Subclass Profile When Compared to Anti-SARS-CoV-2 Antibodies
*Purpose: Both anti-HLA and anti-SARS-CoV-2 antibodies target protein antigens. The aim of the present study was to compare the class and subclass profile of such…
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