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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Expanded Criteria Donor with Severe Acute Kidney Injury: Worth to Use?

    S. Thotsiri, N. Sutharattanapong, C. Janphram, P. Wiwattanathum

    Excellent Center of Organ Transplantation, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

    *Purpose: Because of organ shortage, the world facing problem, expanded criteria donor (ECD) was utilized to increase donor pool. Although long term allograft survival from…
  • 2022 American Transplant Congress

    Time-Dependent Blood Eosinophilia Count Increases the Risk of Kidney Allograft Rejection

    L. Colas1, L. Bui2, C. Kerleau3, M. Lemdani4, K. Autain-Renaudin5, A. Magnan6, M. Giral3, S. Brouard1

    1CRT2I, Université de Nantes, Nantes, France, 2Service de Néphrologie, Centre Hospitalier de Mouscron, Mouscron, Belgium, 3Service de Néphrologie et Immunologie Clinique, CHU de Nantes, Nantes, France, 4Département de Biomathématiques, Université de Lilles, Lilles, France, 5Service d'Anatomie et Cytologie Pathologique, CHU de Nantes, Nantes, France, 6INRAe UMR 0892, Université de Versailles Saint-Quentin Paris-Saclay, Paris, France

    *Purpose: There is growing evidence that type 2 immune effectors (immunoglobulin E, eosinophils, mast cells/basophils) play a role in autoimmune disorders and solid organ transplantation.…
  • 2022 American Transplant Congress

    Liver and Kidney Transplantation from Donation After Circulatory Death Heart Donors in the US: Better Early Outcomes with Normothermic Regional Perfusion versus Cold Flush

    M. Rosenzweig1, R. Ruiz2, E. Martinez1, A. Gupta1, H. Fernandez1, S. Lee1, N. Onaca1, J. Bayer1, G. J. McKenna1, T. Ma1, G. Testa3, A. Wall1

    1Baylor University Medical Center, Dallas, TX, 2Baylor University Medical Center, Fort Worth, TX, 3Baylor Dallas, Dallas, TX

    *Purpose: Donation after circulatory death (DCD) heart donation is increasingly common in the US. The two methods for DCD heart donation are normothermic regional perfusion…
  • 2022 American Transplant Congress

    Pegloticase for Uncontrolled Gout in Kidney Transplant Recipients: Provisional Data Report of a Multicenter, Open-Label, Efficacy and Safety Study

    A. Abdellatif1, L. Zhao2, K. Cherny2, B. Marder2, J. D. Scandling3, K. Saag4

    1Division of Nephrology, Baylor College of Medicine, Houston, TX, 2Horizon Therapeutics PLC, Deerfield, IL, 3Division of Nephrology, Stanford School of Medicine, Stanford, CA, 4Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Gout in kidney transplant (KT) recipients can be severe and particularly challenging to manage. Pegloticase co-therapy with immunomodulators improved urate lowering therapy (ULT) response…
  • 2022 American Transplant Congress

    Are Autoimmune Conditions Disadvantaged Compared to Alcoholic Cirrhosis and Hepatocellular Carcinoma?

    S. S. Keeling

    Baylor College of Medicine, Houston, TX

    *Purpose: Orthotopic liver transplantation (OLT) is a lifesaving therapy for patients with irreversible liver damage caused by autoimmune liver diseases (ALD) including autoimmune hepatitis (AIH),…
  • 2022 American Transplant Congress

    A Model for Medical Device Innovation in Transplantation: Using the Biodesign Process to Address the Impact of Warm Ischemic Injury

    K. Hansen1, J. Wall2

    1University of California San Francisco, San Francisco, CA, 2Stanford University, Palo Alto, CA

    *Purpose: The impact of warming during second warm-ischemia (anastomosis) of kidney transplantation has been increasingly recognized in the literature. The outsized effect on delayed graft…
  • 2022 American Transplant Congress

    Thymoglobulin Induction Protocol: Quality Improvement Project via Clinical Audit

    S. Mouawad1, J. Dann1, A. Kumar2, S. Rao3

    1University of Virginia Health System, Charlottesville, VA, 2Nephrology, University of Virginia, Charlottesville, VA, 3University of Virginia, Charlottesville, VA

    *Purpose: The aim of our study was to analyze the adequacy of the thymoglobulin (rATG) induction protocol for the expanding and higher complexity kidney transplant…
  • 2022 American Transplant Congress

    Long-Term Outcomes in Living-Donor Preemptive Kidney Transplants: Results from a Brazilian Single-Center Cohort Study

    B. Beraldo, L. R. Requião-Moura, M. Gaspar, R. D. Foresto, H. Tedesco-Silva, J. Medina-Pestana

    Nephrology Division - Hospital do Rim, Universidade Federal de São Paulo, São Paulo, Brazil

    *Purpose: To evaluate predictors of long-term graft function and unfavorable outcomes in living-donor preemptive kidney transplant recipients.*Methods: A single-center cohort study enrolled 223 living-donor preemptive…
  • 2022 American Transplant Congress

    Characteristics and Outcomes of Anhepatic Patients Listed for Liver Retransplantation

    R. G. Kathawate1, T. Ibeabuchi2, P. Abt2, T. Bittermann2

    1University of Michigan, Ann Arbor, MI, 2University of Pennsylvania, Philadelphia, PA

    *Purpose: The frequency and outcomes of anhepatic patients listed for transplantation in the United States has not been previously described. The United Network for Organ…
  • 2022 American Transplant Congress

    Histologic Predictors of Graft Loss in Early Clinically Indicated Biopsies After Kidney Transplantation

    M. Ajaimy1, V. Hemmige2, L. E. Liriano-Ward3, Y. Azzi1, S. Kapoor4, P. Loarte1, C. Pynadath5, A. Colovai1, E. Akalin6

    1Einstein-Montefiore Transplant Center, Bronx, NY, 2Montefiore Medical Center, Bronx, NY, 3Transplant, Montefiore Medical Center, Bronx, NY, 4Montefiore Medical Center, New York, NY, 5Einstein-Montefiore Transplant Center, Scarsdale, NY, 6Albert Einstein College of Medicine, Montefiore Medical Ctr, Bronx, NY

    *Purpose: We aimed to investigate histopathological predictors of graft lost in patients who underwent clinically indicated biopsies for worsening kidney function and/or proteinuria within 3…
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