ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Long-Term Outcomes in Living-Donor Preemptive Kidney Transplants: Results from a Brazilian Single-Center Cohort Study

    B. Beraldo, L. R. Requião-Moura, M. Gaspar, R. D. Foresto, H. Tedesco-Silva, J. Medina-Pestana

    Nephrology Division - Hospital do Rim, Universidade Federal de São Paulo, São Paulo, Brazil

    *Purpose: To evaluate predictors of long-term graft function and unfavorable outcomes in living-donor preemptive kidney transplant recipients.*Methods: A single-center cohort study enrolled 223 living-donor preemptive…
  • 2022 American Transplant Congress

    The Role of Advanced Practice Providers in Liver Transplant Centers

    S. Nargiso, L. Sher, V. Tristan

    Keck Medical Center at University of Southern California, Los Angeles, CA

    *Purpose: Care for the liver transplant (LT) recipient requires expertise and consistency. Due to the rotation of trainees and the emphasis on surgical experience for…
  • 2022 American Transplant Congress

    A Randomized, Controlled, Double-blind Trial Of Inulin To Boost Response To A Third Covid-19 Vaccine Dose In Kidney Transplant Recipients.

    J. Singer1, M. Tunbridge2, T. Salehi3, G. Perkins4, B. Grubnor-Bauk5, B. Sim3, T. Ying6, P. T. Coates3, S. J. Chadban1

    1Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia, 2Renal Medicine, Royal Adelaide Hospital, Adelaide, Australia, 3Royal Adelaide Hospital, Adelaide, Australia, 4School of Biological Sciences, University of Adelaide, Adelaide, Australia, 5Adelaide University, Adelaide, Australia, 6Royal Prince Alfred Hospital, Sydney, Australia

    *Purpose: Kidney transplant recipients (KTR) commonly exhibit inadequate responses to 2-dose COVID-19 vaccination schedules and remain at increased risk of severe COVID-19. Gut dysbiosis is…
  • 2022 American Transplant Congress

    Deletion of AIF-1 Promotes Kidney Reparative Macrophages and Prevents Fibrosis

    I. Husain, A. Dangi, X. Luo

    Duke University School of Medicine, Durham, NC

    *Purpose: A major etiology contributing to poor allograft survival is the inevitable ischemic insult it incurs during transplantation. Macrophages are key players in ischemia-reperfusion injury,…
  • 2022 American Transplant Congress

    An In Depth Assessment of Unsuccessful DCD Donor Procurement Attempts: Areas for Improvement

    M. Rosenzweig, M. Finotti, E. Martinez, S. Lee, A. Gupta, A. Wall, J. Bayer, H. Fernandez, N. Onaca, R. Ruiz, G. J. McKenna

    Baylor Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX

    *Purpose: DCD donors are a key way to expand allograft supply but an aggressive strategy of pursuing DCD liver allografts is associated with significant number…
  • 2022 American Transplant Congress

    Pegloticase Use in Renal Transplant Recipients with Gout: Findings from an Insurance Claims Database Study

    C. A. Shadur1, B. Marder2, C. Vesel2, B. LaMoreaux2

    1Iowa Kidney Physicians, Des Moines, IA, 2Horizon Therapeutics plc, Deerfield, IL

    *Purpose: Kidney transplant (KT) recipients have high gout incidence due to reduced eGFR and medication use associated with hyperuricemia.1 Oral urate-lowering therapies in KT patients…
  • 2022 American Transplant Congress

    Donor and Recipient Age Matching for Kidney Transplantation: A Machine Learning Approach

    J. Kim, J. Ahn, A. Massie, D. Segev, S. Bae

    Johns Hopkins, Baltimore, MD

    *Purpose: Under the concept of ‘longevity matching,’ the Kidney Allocation System favors matching younger deceased donors with younger kidney transplant (KT) candidates. However, it remains…
  • 2022 American Transplant Congress

    A Model for Medical Device Innovation in Transplantation: Using the Biodesign Process to Address the Impact of Warm Ischemic Injury

    K. Hansen1, J. Wall2

    1University of California San Francisco, San Francisco, CA, 2Stanford University, Palo Alto, CA

    *Purpose: The impact of warming during second warm-ischemia (anastomosis) of kidney transplantation has been increasingly recognized in the literature. The outsized effect on delayed graft…
  • 2022 American Transplant Congress

    Anti-HLA Antibodies Do Not Increase in Kidney Transplant Recipients During COVID-19 Infection

    A. Girnita1, L. Wang1, P. Ahearn1, A. Colovai2, M. Fernandez-Vina1, E. Woodle3, T. Yalamarti1, M. Menon4, Y. Azzi2, M. Melcher1, R. Bray5, H. Gebel5, P. Cravedi4, J. Maltzman1, E. Akalin2

    1Stanford University, Palo Alto, CA, 2Albert Einstein College of Medicine, New York, NY, 3University of Cincinnati, Cincinnati, OH, 4Mount Sinai, New York, NY, 5Emory University Hospital, Atlanta, GA

    *Purpose: To determine if HLA allo-antibody levels are affected by COVID-19 in renal transplanted patients and to compare the immunoglobulin class and subclass profiles as…
  • 2022 American Transplant Congress

    Time-Dependent Blood Eosinophilia Count Increases the Risk of Kidney Allograft Rejection

    L. Colas1, L. Bui2, C. Kerleau3, M. Lemdani4, K. Autain-Renaudin5, A. Magnan6, M. Giral3, S. Brouard1

    1CRT2I, Université de Nantes, Nantes, France, 2Service de Néphrologie, Centre Hospitalier de Mouscron, Mouscron, Belgium, 3Service de Néphrologie et Immunologie Clinique, CHU de Nantes, Nantes, France, 4Département de Biomathématiques, Université de Lilles, Lilles, France, 5Service d'Anatomie et Cytologie Pathologique, CHU de Nantes, Nantes, France, 6INRAe UMR 0892, Université de Versailles Saint-Quentin Paris-Saclay, Paris, France

    *Purpose: There is growing evidence that type 2 immune effectors (immunoglobulin E, eosinophils, mast cells/basophils) play a role in autoimmune disorders and solid organ transplantation.…
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