ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Is Low Systemic Fibrinolytic Activity During the Anhepatic Phase Liver Transplant Surgery Associate with the Dreaded Post-Operative Complication of Hepatic Artery Thrombosis?

    H. B. Moore1, Y. Bababekov1, J. Pomposelli1, T. Ferrell1, F. Azam1, M. Adams2, D. Yoeli1, R. Choudhury1, M. Wachs2, E. Pomfret1, T. Nydam1

    1University of Colorado, Aurora, CO, 2Childrens Hospital Colorado, Aurora, CO

    *Purpose: Removal of the native liver during transplantation results in impaired clearance of clot degrading proteins and activation of fibrinolysis as appreciated by Starzl in…
  • 2021 American Transplant Congress

    Highly Sensitized Simultaneous Liver-kidney Transplant Recipients Show a Reduction in Panel Reactive Antibodies and No Kidney Rejection 1-year Post-transplant

    M. Moaddab, J. V. Nolte Fong, C. M. Mobley, A. Saharia, M. J. Hobeika, R. McMillan, S. G. Yi, R. J. Knight, A. Gaber, R. Ghobrial

    Houston Methodist Hospital, Houston, TX

    *Purpose: The liver is unique in that it is considered an immunologically tolerant organ against graft destruction by antibodies. Simultaneous liver-kidney transplantation (SLKT) are often…
  • 2021 American Transplant Congress

    Implementation of an Alcohol Screening Program Identifies Active Pre-transplant Drinking and Allows Engagement in Chemical Dependency Treatment

    N. Lim1, T. Leventhal1, M. Thomson1, M. Hassan1, J. Thompson1, S. Chinnakotla2, V. Kirchner2, T. Pruett2, R. Kandaswamy2, V. Humphreville2, A. Adams2, J. Lake1

    1Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, 2Division of Transplantation, University of Minnesota, Minneapolis, MN

    *Purpose: Alcohol (ETOH) is an important cause of cirrhosis in the US today. Screening patients for ETOH use prior to LT is important to identify…
  • 2021 American Transplant Congress

    A Multi-institutional Study of Renal Outcomes in Uterus Transplantation

    D. Sawinski1, L. Johannesson2, J. Kristen3, J. Fronek3, P. Porrett4

    1Hospital of the University of Pennsylvania, Philadelphia, PA, 2Department of Surgery, Baylor University Medical Center, Dallas, TX, 3Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 4University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Pregnancy and calcineurin inhibitor-based immunosuppression represent potential renal stressors for uterus transplant (UTx) recipients, many of whom have Mayer-Rokitanksy-Kuster-Hauser (MRKH) syndrome and associated renal…
  • 2021 American Transplant Congress

    Recovery After Extended Static Cold Storage Preservation Using Subnormothermic Machine Perfusion in VCA

    M. Goutard1, R. J. de Vries1, A. G. Lellouch1, E. Lupon1, C. Pendexter1, S. N. Tessier1, M. A. Randolph1, L. Lantieri2, C. L. Cetrulo1, K. Uygun1

    1Massachusetts General Hospital, Harvard Medical School, Shriners Hospitals for Children, Boston, MA, 2Hôpital Européen Georges Pompidou, Paris, France

    *Purpose: Vascularized composite allografts (VCA) are more sensitive to cold ischemia than solid organ transplants due to the remaining metabolism in skeletal muscle cells. In…
  • 2021 American Transplant Congress

    Myeloid Foxo1-β-catenin Axis Regulates Hedgehog/Gli1 Signaling and Controls NLRP3-Mediated Innate Immune Responses in Sterile Inflammatory Liver Injury

    D. Xu, C. Li, M. Sheng, Y. Lin, Y. Tian, Y. Zhan, A. J. Coito, R. W. Busuttil, D. G. Farmer, J. W. Kupiec-Weglinski, B. Ke

    Surgery, Dumont - UCLA Transplant Center, Los Angeles, CA

    *Purpose: Foxo1 plays important roles in cell metabolism, oxidative stress, inflammation, and apoptosis. Activation of Hedgehog/Gli1 signaling regulates cell growth, differentiation, and immune function. However,…
  • 2021 American Transplant Congress

    Characterisation of Distinct Graft Infiltrates Following Cellular Therapy in Kidney Transplant Recipients

    M. O. Brook1, P. N. Harden2, I. Roberts2, W. R. Mulley3, J. Hester1, M. E. Reinders4, F. Issa1

    1Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, 2Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom, 3Department of Nephrology, Monash Medical Centre, Melbourne, Australia, 4Division of Nephrology and Transplant Center, Leiden University Medical Center, Leiden, Netherlands

    *Purpose: Cellular therapy is an emerging treatment in the field of clinical transplantation with the potential to improve both short and long-term transplant outcomes. We…
  • 2021 American Transplant Congress

    Food Insecurity and Impact on Transplant Outcomes in Pediatric Kidney Transplant Recipients

    A. Moin, P. Verghese, R. Engen, D. Matossian

    Pediatric Nephrology, Lurie Children's Hospital, chicago, IL

    *Purpose: Food insecurity (FI), defined as inconsistent access to food or worry over shortage of food that prevents an active and healthy life, has not…
  • 2021 American Transplant Congress

    Nutrition, Body Habitus, and Food Insecurity, in Pediatric Kidney Transplant Recipients

    A. Wilkerson1, J. Figueroa1, C. Kang1, R. Garro2, M. Kamel1, R. P. George2

    1Emory University, Atlanta, GA, 2Emory University and Children's Healthcare of Atlanta, Atlanta, GA

    *Purpose: Appropriate nutrition and physical activity are critical for optimal post-transplant recovery and long term outcomes, especially in pediatric populations. Both malnutrition and obesity are…
  • 2021 American Transplant Congress

    A2 to B Deceased Donor Renal Transplantation Outcome Analysis: Single Center Experience

    S. Bindroo, M. Doshi

    Nephrology, University of Michigan, Ann Arbor, MI

    *Purpose: Initial experience under kidney allocation system (KAS) implemented in December 2014 showed equivalent outcomes for A2 to B kidney transplantation compared with ABO compatible…
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