ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Right Kidneys and Kidneys with Complex Anatomy are More Likely to be Transplanted to the Waiting List in a National Kidney Paired Donation Program

    N. Osbun1, A. Thomas2, A. Waterman3, J. Veale1, D. Segev2, D. Leeser4

    1Urology, University of California Los Angeles, Los Angeles, CA, 2Johns Hopkins University, Baltimore, MD, 3University of California Los Angeles, Los Angeles, CA, 4East Carolina University, Greenville, NC

    *Purpose: In the era of laparoscopic donor nephrectomy, there is a preference for left kidneys with a single renal artery. In paired exchange, the receiving…
  • 2021 American Transplant Congress

    The Effect of Daratumumab (Dara, Humanized Anti-CD38 Monoclonal Antibody) on Immune Cells In Vitro and in a HLA-Sensitized Kidney Transplant Patient (HS KTx Pt) Desensitized (DES) with Dara

    S. Ge1, M. Chu1, A. De Guzman1, E. Ortiz1, A. Vo2, N. Ammerman2, S. C. Jordan2, M. Toyoda1

    1Transplant Immunology Laboratory, Cedars Sinai Medical Center, Los Angeles, CA, 2Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA

    *Purpose: Antibody-Mediated Rejection (ABMR), primarily mediated by B cells, plasma cells (PC) and antibodies (Ab), is an obstacle for successful transplantation in HS KTx Pts.…
  • 2021 American Transplant Congress

    Additional Value to Participation in a National Paired Kidney Exchange Program: Exploring Characteristics of Chain End Living Donors and Waitlist Recipients

    N. Osbun1, A. Thomas2, M. Cooper3, S. Flechner4, D. Segev2, J. Veale1

    1Urology, University of California Los Angeles, Los Angeles, CA, 2Johns Hopkins University, Baltimore, MD, 3Medstar Georgetown Transplant Institute, Washington DC, DC, 4Cleveland Clinic, Cleveland, OH

    *Purpose: Non-directed kidney donors can initiate living donor chains that end to patients on the deceased donor waitlist. While many studies of paired exchange practices…
  • 2021 American Transplant Congress

    Infectious Complications After Belatacept Conversion in Kidney Transplant

    J. E. Marvin1, D. Amenyedor1, M. M. Azar2, K. Belfield1, V. Do1, R. Formica3, E. Cohen1

    1Pharmacy, Yale New Haven Hospital, New Haven, CT, 2Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, 3Section of Nephrology, Yale School of Medicine, New Haven, CT

    *Purpose: Tacrolimus (tac), a calcineurin inhibitor, is associated with multiple adverse effects when used for immunosuppression following kidney transplant (KT). Belatacept (bela) is a monoclonal…
  • 2021 American Transplant Congress

    Kidney Donor Risk Index: Significance as a Predictor of Kidney Transplant Outcomes Beyond Allograft Survival, Analysis of 18 Adjusted Regression Models Involving Adult Deceased Donor Kidney Recipients

    A. Santos, E. Bueno, M. A. Leghrouz

    University of Florida, Gainesville, FL

    *Purpose: We aimed to study the role of kidney donor recipient index (KDRI) as a predictor for multiple transplant-related outcomes in adult deceased-donor (DD) kidney…
  • 2021 American Transplant Congress

    Oxalate Nephropathy After Kidney Transplant: Defining Histological Patterns, Contributing Factors and Graft Outcome

    N. Jakob1, A. Chuu1, J. Ninan1, E. Lim1, N. Zhang1, H. Amer2, F. Cosio2, H. Wadei3, M. Ryan1, C. Cortese3, L. Cornell2, M. Keddis1

    1Nephrology, Mayo Clinic, Scottsdale, AZ, 2Nephrology, Mayo Clinic, Rochester, MN, 3Nephrology, Mayo Clinic, Jacksonville, FL

    *Purpose: The objective of this study is to evaluate KTx recipients with biopsy proven oxalate nephropathy (ON) to better define risk factors, histologic patterns and…
  • 2021 American Transplant Congress

    Worsening Impact of Acute Kidney Rejection on Long Term Graft Survival from 2000 to 2014

    D. Leeser1, W. Irish1, K. Ravindra2, V. Villani2, A. Connor2, J. Tuttle1

    1Surgery, East Carolina University, Greenville, NC, 2Surgery, Duke University, Durham, NC

    *Purpose: Acute rejection (AR) has been shown to impact graft survival after kidney transplant (KTx), however there is limited data on its impact on long…
  • 2021 American Transplant Congress

    Outcomes of Kidney Transplant Recipients With Sickle Cell Disease: An Analysis of the 2000-2019 UNOS/OPTN Database

    N. Leeaphorn1, C. Thongprayoon2, C. Jadlowiec3, A. Chewcharat4, P. Hansrivijit5, S. Katari1, P. Vaitla6, L. Cummings1, M. Cooper7, W. Cheungpasitporn2

    1Saint Luke's Health System, Kansas City, MO, 2Mayo Clinic, Rochester, MN, 3Mayo Clinic, Phoenix, AZ, 4Mount Auburn Hospital, Cambridge, MA, 5University of Pittsburgh Medical Center Pinnacle, Harrisburg, PA, 6University of Mississippi Medical Center, Jackson, MS, 7Medstar Georgetown Transplant Institute, Washington, DC

    *Purpose: Lower patient survival has been observed in sickle cell disease (SCD) patients who go on to receive a kidney transplant. This study aimed to…
  • 2021 American Transplant Congress

    Economic and Clinical Benefit of Cmv Matching in Kidney Transplantation

    D. Axelrod1, S. Chang2, A. Olyaei3, D. Malinoski3, D. Norman3, K. Lentine4, M. Schnitzler4, D. Segev5, J. Lockridge3

    1Univ of Iowa, Iowa City, IA, 2Washington Univ, Seattle, WA, 3Oregon Health Sciences Univ, Portland, OR, 4Saint Louis Univ, Saint Louis, MO, 5Johns Hopkins, Baltimore, MD

    *Purpose: Recently, kidney transplant (KTx) centers in Oregon collaborated to preferentially allocate cytomegalovirus-seronegative (CMV D-) kidneys to seronegative recipients (CMV R-), successfully reducing high-risk CMV…
  • 2021 American Transplant Congress

    The Effect of Delayed Graft Function on Early versus Late Mortality Following Kidney Transplantation

    W. Irish1, Y. Fu2, D. B. Leeser1, K. V. Ravindra3, C. Haisch1, J. Tuttle1

    1Surgery, East Carolina University, Greenville, NC, 2Mathematics, East Carolina University, Greenville, NC, 3Surgery, Duke University, Durham, NC

    *Purpose: Delayed graft function (DGF) is associated with increased risk of long-term graft survival but it’s impact on patient survival has not been studied. Using…
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