2021 American Transplant Congress
Development and Validation of a Novel Peripheral Blood Based Gene Signature for Acute Rejection Following Renal Transplantation
Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
*Purpose: The aim of this study is to utilize advanced machine learning methods to construct a peripheral blood-based gene signature for acute rejection following kidney…2021 American Transplant Congress
Profound Opportunities Lost: Patients with High Priority for Ideal Donor Kidneys That are Not Placed on the Kidney Transplant Waiting List
1Cleveland Clinic Foundation, Cleveland, OH, 2Columbia University, New York, NY
*Purpose: The national Kidney Allocation System(KAS) prioritizes patients with high (top 20%) Estimated Post-Transplant Survival (EPTS) with expedited access to high quality deceased donor kidneys.…2021 American Transplant Congress
Predicting Post-transplant Death and Graft Loss Risk: Insight at Listing
1CareDx, Brisbane, CA, 2Saint Louis University, St. Louis, MO
*Purpose: Prognostication models for post-transplant outcomes deriving inputs from information collected on donor (DDR/LDR), candidate (TCR) and transplant recipient (TRR) registrations can provide useful information…2021 American Transplant Congress
DCD Heart Donation: Impact on Organ Yield
United Network for Organ Sharing, Richmond, VA
*Purpose: Recent advances in technology and recovery procedures has enabled donation after circulatory death (DCD) heart donation resulting in a significant increase in the number…2021 American Transplant Congress
Gain of Function Mutations in Latent Membrane Protein 1 of Epstein Barr Virus are Associated with Increased Risk of Post-Transplant Lymphoproliferative Disorder
*Purpose: Post-transplant lymphoproliferative disorder (PTLD) remains a serious problem in the pediatric transplant population. Clinical Trials of Organ Transplantation in Children (CTOTC)-06 is a prospective…2021 American Transplant Congress
The Effect of the Affordable Care Act on Insurance Status, Waitlist, and Transplant Outcomes in Liver Transplantation
*Purpose: The Affordable Care Act (ACA) intended to expand Medicaid to cover all adults with income below 138% of federal poverty level. We describe the…2021 American Transplant Congress
Validation of a Novel Gene Expression Biomarker of Rejection Following Liver Transplantation
*Purpose: Non-invasive biomarkers distinguishing early signs of immune activation vs. quiescence could more objectively guide immunosuppression management after liver transplantation (LT). Our aim was to…2021 American Transplant Congress
Identification of Distinct Blood Monocyte Phenotypes from Transplant Kidney Recipients Undergoing Cellular (TCMR) and Mixed Antibody Mediated Rejection (ABMR)
Starzl Transplantation Institute, Pittsburgh, PA
*Purpose: Monocytes play an important role in immune defense by initiating adaptive immunity. They are heterogeneous, plastic, and present different subsets: classical (CD14++CD16-), intermediate (CD14+CD16+),…2021 American Transplant Congress
Significance of Repeated 1r Rejections in Heart Transplantation
1Yale New Haven Hospital, New Haven, CT, 2Yale University School of Medicine, New Haven, CT
*Purpose: 1R rejection is commonly seen in routine post-transplant biopsies. While presence of occasional 1R rejection is not considered to be detrimental, the significance of…2021 American Transplant Congress
Clinical and Molecular Profiling Can Help in Predicting the Response to Alemtuzumab Treatment in Kidney Transplant Recipients with Severe or Glucocorticoid-Resistant Acute Rejection
*Purpose: Alemtuzumab is an effective drug for the treatment of severe or glucocorticoid-resistant acute kidney allograft rejection (AR), but can also cause severe adverse events.…
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