Abstracts Archive - Page 235 of 1683 - ATC Abstracts

2021 American Transplant Congress
Unclear Implications of Tacrolimus Time in Therapeutic Range as a Predictor of Acute Rejection in Renal Transplant Recipients Undergoing Early Corticosteroid Withdrawal
D. Pierce, P. West-Thielke, Z. Hajjiri, S. Gaitonde, I. Tzvetanov, E. Benedetti, A. Lichvar
University of Illinois at Chicago, Chicago, IL
*Purpose: Tacrolimus (TAC) demonstrates a wide intra- and inter-patient variability (IPV) necessitating therapeutic drug monitoring. The purpose of this study is to determine the impact…
2021 American Transplant Congress
Immunologic Benefits of Maternal Living Donor Allografts in Pediatric Liver Transplantation: Less Rejection Episodes and No Evidence of De Novo Allosensitization
A. Barbetta¹, G. Meeberg², B. Rocque¹, S. Barhouma³, S. Gilmour⁴, F. Faytrouni⁵, O. Guttman⁵, P. Campbell⁴, J. Shapiro², J. Emamaullee¹
¹Surgery, Abdominal Transplant, University of Southern California, Los Angeles, CA, ²Surgery, University of Alberta, Edmonton, AB, Canada, ³University of Southern California, Los Angeles, CA, ⁴University of Alberta, Edmonton, AB, Canada, ⁵University of British Columbia, Vancouver, BC, Canada
*Purpose: Living donor liver transplantation (LDLT) offers improved graft and patient survival in pediatric liver transplant (LT) recipients. Prior studies have suggested immunological advantage when…
2021 American Transplant Congress
Elevated Tacrolimus Levels in Hospitalized Organ Transplant Recipients with COVID-19
K. Mecadon¹, A. Hardesty², K. Vieira³, R. Rogers³, B. Merhi⁴, A. J. Osband⁵, G. Bayliss⁴, R. Gohh⁴, P. Morrissey⁵, D. Farmakiotis³
¹Department of Pharmacy, Rhode Island Hospital, Providence, RI, ²Department of Internal Medicine, Residency, Warren Alpert Medical School of Brown University, Providence, RI, ³Division of Infectious Diseases, Warren Alpert Medical School of Brown University, Providence, RI, ⁴Division of Nephrology, Warren Alpert Medical School of Brown University, Providence, RI, ⁵Department of Surgery (Transplantation), Warren Alpert Medical School of Brown University, Providence, RI
*Purpose: The effect of COVID-19 on immunosuppressant drug levels in organ transplant recipients (OTRs) has not been adequately studied.*Methods: We retrospectively studied hospitalized adult (>18-year-old)…
2021 American Transplant Congress
COVID-19 Transmission within One Year from Pancreas and Kidney Recipients
H. Sarumi, J. Fisher, B. Johnson, T. Pruett
University of Minnesota, Minneapolis, MN
*Purpose: The current pandemic has created uncertainty surrounding the transmission of COVID-19. It was recently published that in the general population, household contacts have a…
2021 American Transplant Congress
When One Size Does Not Fit All: Geographically Heterogeneous Liver Distribution
M. A. Mankowski¹, S. Gentry², D. Segev³, N. Trichakis⁴
¹KAUST, Thuwal, Saudi Arabia, ²US Naval Academy, Annapolis, MD, ³JHU, Baltimore, MD, ⁴MIT, Boston, MA
*Purpose: The new liver allocation system prioritizes distribution within acuity circles, instead of within DSAs. Acuity circles have the same radius around all donor hospitals…
2021 American Transplant Congress
Improved Patient Survival in DCD Liver Transplantation
O. Bushara¹, J. Alhalel¹, H. Azad¹, T. Cerri², S. Zafer², J. C. Caicedo¹
¹Department of Surgery, Division of Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Rosalind Franklin Medical School, Chicago, IL
*Purpose: We aim to investigate longitudinal outcomes in DCD liver transplantation over a 10-year period and elucidate trends in patient survival, biliary complication rates, and…
2021 American Transplant Congress
Baseline Levels of Dd-cf Dna After Pancreas Transplantation: Using Dd-cfdna as an Indicator for Pancreas Rejection and Biopsy Avoidance
A. Yoo, I. Qian, A. Riedel, C. Cazac, A. Bartosic, J. S. Bromberg, J. Scalea
Department of Surgery, Division of Transplant, University of Maryland School of Medicine, Baltimore, MD
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) testing, which has been previously validated for monitoring kidney transplant (KTx) rejection, may provide an alternative to pancreas biopsy that…
2021 American Transplant Congress
Better Dialysis Facility Five-Star Rating is Associated with Increased Listing for Kidney Transplantation
J. T. Adler¹, L. Xiang¹, J. S. Weissman¹, J. R. Rodrigue², R. E. Patzer³, S. S. Waikar⁴
¹Surgery, Brigham and Women's Hospital, Boston, MA, ²Surgery, Beth Israel Deaconess Medical Center, Boston, MA, ³Surgery, Emory University, Atlanta, GA, ⁴Medicine, Boston Medical Center, Boston, MA
*Purpose: Improving the quality of dialysis care for patients with end stage kidney disease (ESKD) is a national clinical and policy priority: the Advancing American…
2021 American Transplant Congress
Artificial Neural Network Application for MELDNa Prediction
L. Pruinelli¹, M. Nguyen¹, S. Olson¹, J. Zhou¹, J. Schold², T. Pruett¹, S. Ma¹, G. Simon¹
¹University of Minnesota, Minneapolis, MN, ²Cleveland Clinic Foundation, Cleveland, OH
*Purpose: The adoption of MELDNa decreased 90-days mortality on patients waiting for liver transplant (LT); however, there are no tools available to predict MELDNa trajectories…
2021 American Transplant Congress
Combined CD11b/CD40 Blockade is Superior to CD40 Blockade Alone in Prolonging Survival in Pig-to-Nonhuman Primate Renal Xenotransplantation
D. A. Faber¹, B. Lovasik¹, A. Matar¹, C. Breeden¹, S. Kim¹, A. Adams²
¹Surgery, Emory University School of Medicine, Atlanta, GA, ²Surgery, University of Minnesota, Minneapolis, MN
*Purpose: Blockade of the CD40/CD154 pathway is highly effective in preventing rejection in pig-to-nonhuman primate (NHP) xenotransplantation models. Clinical translation of anti-CD154 mAbs, however, has…