ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Letermovir Prophylaxis in Solid Organ Transplant – CMV Breakthrough and Tacrolimus Drug Interaction

    R. Winstead1, D. Kumar1, A. Brown1, I. Yakubu1, C. Song1, L. Thacker2, G. Gupta1

    1Virginia Commonwealth University Health, Richmond, VA, 2Virginia Commonwealth University, Richmond, VA

    *Purpose: Valganciclovir is the preferred drug for cytomegalovirus (CMV) prophylaxis in solid organ transplantation. A limitation to its use is profound myelosuppression. Letermovir is a…
  • 2021 American Transplant Congress

    Donor Derived Cell Free DNA Identifies Rejection in Simultaneous Pancreas Kidney Transplant Recipients

    M. Williams1, S. Ghosh2, L. L. Jenkins2, M. Hertl1, S. Saltzberg3, V. Peev3, E. Chan1, E. Hollinger1, E. Schadde1, O. Olaitan1

    1Department of Surgery, Rush University Medical Center, Chicago, IL, 2CareDx, Inc., Brisbane, CA, 3Department of Internal Medicine, Rush University Medical Center, Chicago, IL

    *Purpose: Increased level of donor-derived cell-free DNA (dd-cfDNA) has proven to be a sensitive marker for allograft rejection after solid organ transplant, particularly heart and…
  • 2021 American Transplant Congress

    Intravenous Immunoglobulin Protects Liver Allograft from Ischemia Reperfusion Injury in Human Liver Transplantation

    S. Yokota, J. C. Alonso-Escalante, R. P. Tindall, K. R. Tabar, L. Machado, T. Uemura, N. L. Thai

    Department of Surgery, Allegheny General Hospital, Pittsburgh, PA

    *Purpose: Ischemia/reperfusion (I/R) injury following prolonged cold storage has a significant impact on early and late human liver transplantation (LTx) outcomes. Prevention of I/R injury…
  • 2021 American Transplant Congress

    Accounting for Survivor Bias in Transplant Benefit Models

    E. M. Schnellinger1, E. Cantu2, M. O. Harhay1, D. E. Schaubel1, S. E. Kimmel1, A. J. Stephens-Shields1

    1Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 2Department of Surgery, Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA

    *Purpose: The lung allocation system in the U.S. prioritizes lung transplant candidates based on estimated pre- and post-transplant survival. However, these models do not account…
  • 2021 American Transplant Congress

    Knowledge and Attitudes Towards Organ Donation Among Asian Americans in Queens

    M. T. Li, G. C. Hillyer, D. W. Kim, K. L. King, S. A. Husain, S. Mohan

    Columbia University, New York, NY

    *Purpose: Asian Americans have the lowest organ donation registration rates in the United States (U.S.). We attempted to identify organ donation barriers among Chinese and…
  • 2021 American Transplant Congress

    Nurse and Nurse Practitioner-lead Monoclonal Antibody Initiative for Solid Organ Transplant (sot) Recipients with Covid-19

    W. Cochran1, R. Avery2, D. Brennan2, N. Lawrence2, A. Brown2, S. Sullivan2, B. Adams2, M. McCarthy2, S. Ellis2, F. Naqvi2, E. Kraus2, N. Alachkar2, S. Alasfar2, F. Al Ammary2, J. Horn2, L. Hartman2, L. Fessler2, S. Purekal2, Z. Siddiqui2, D. Carter2, J. Ficke2, M. Kantsiper2, L. Boyer2, I. Gupta2, A. Gurakar2, D. Ostrander2, J. Langlee2, S. Shoham2, K. Marr2, P. Shah2

    1Johns Hopkins Comprehensive Transplant Center, Baltimore, MD, 2Johns Hopkins, Baltimore, MD

    *Purpose: Monoclonal antibody (mAB) infusion (bamlanivimab or casirivimab/imdevimab) for symptomatic, non-hypoxemic, high-risk outpatients with COVID-19 infection, is an available early intervention for COVID-19+ SOT recipients.…
  • 2021 American Transplant Congress

    Hospitalization in the First Year After Kidney Transplantation: Analyses to Identify Common Predictors of Risk Across Recipient Sensitization Groups

    A. Santos, E. Bueno, M. A. Leghrouz

    University of Florida, Gainesville, FL

    *Purpose: We investigated the risk of hospitalization associated with baseline risk factors in adult deceased donor (DD) kidney transplant (KT) recipients (KTRs) stratified into calculated…
  • 2021 American Transplant Congress

    Machine Learning Informs Utility-Based Non-Directed Living Liver Donor Allocation

    K. Bambha1, J. Perkins1, M. Sturdevant1, S. W. Biggins1, R. Bakthavatsalam1, P. Healey2, A. Dick2, J. Reyes1

    1University of Washington, Seattle, WA, 2Seattle Children's, Seattle, WA

    *Purpose: To maximize non-directed living liver donor graft utility, we developed analytic models predicting 10-year graft survival post liver transplant (LT).*Methods: We analyzed OPTN living…
  • 2021 American Transplant Congress

    A Multi-institutional Study of Renal Outcomes in Uterus Transplantation

    D. Sawinski1, L. Johannesson2, J. Kristen3, J. Fronek3, P. Porrett4

    1Hospital of the University of Pennsylvania, Philadelphia, PA, 2Department of Surgery, Baylor University Medical Center, Dallas, TX, 3Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 4University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Pregnancy and calcineurin inhibitor-based immunosuppression represent potential renal stressors for uterus transplant (UTx) recipients, many of whom have Mayer-Rokitanksy-Kuster-Hauser (MRKH) syndrome and associated renal…
  • 2021 American Transplant Congress

    A Noninvasive Diagnostic Approach for Molecular Monitoring of Face Transplant Recipients

    C. Snopkowski1, P. Rabbani2, H. Yang1, Z. Berman2, G. Diep2, C. Li1, T. Muthukumar1, R. Ding1, D. Ceradini2, M. Suthanthiran1

    1Weill Cornell Medical Institute, Department of Medicine, Division of Nephrology, NY, NY, 2NYU Langone Health, Hansjörg Wyss Department of Plastic Surgery, NY, NY

    *Purpose: Skin biopsies are currently the gold standard for evaluating the inflammatory status of face allografts. However, “tape stripping” is emerging as a noninvasive technique…
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