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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Risk Factors Associated with ICU Admission and Death in Patients Hospitalized with COVID-19 Differ Between Solid Organ Transplant and Non-Solid Organ Transplant Patients

    J. Schaenman, H. Byford, T. R. Grogan, Y. Motwani, O. Beaird, M. Kamath, E. Lum, K. Meneses, D. Sayah, D. Vucicevic, S. Saab

    David Geffen School of Medicine at UCLA, Los Angeles, CA

    *Purpose: Despite the large numbers of reports on patient risk factors for poor clinical outcomes with COVID-19, little is known about how these risks may…
  • 2022 American Transplant Congress

    Patient-Reported Barriers to Living Kidney Donor Follow-Up

    B. Orandi, R. Reed, H. Qu, G. Owens, S. Brooks, C. Killian, V. Kumar, S. Sheikh, R. Cannon, C. Lewis, J. Locke

    University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Despite regulations mandating follow-up laboratory testing for living kidney donors, less than half of transplant centers are in compliance. We sought to understand barriers…
  • 2022 American Transplant Congress

    Association Between Allograft Gene Expression and Acute Cellular Rejection Grade in Heart Transplant Recipients

    A. Kao1, K. Haffey2, K. T. Gondi3, J. Linard2, C. Knutson2, K. Morgan2, L. Teterina2, S. Williams2, K. Oreschak4, H. Zhang4

    1St. Luke's Health System Kansas City Mid America Heart Institute, Kansas City, MO, 2St. Luke's, Kansas City, MO, 3University of Michigan, Ann Arbor, MI, 4CareDx, South San Francisco, CA

    *Purpose: Endomyocardial biopsy (EMB) remains the gold standard in acute rejection (AR) surveillance in heart transplantation (HT) despite interpretation subjectivity and low concordance rates between…
  • 2022 American Transplant Congress

    Association Between Histopathological Features on Implantation Renal Biopsies and Graft Outcomes and Kdpi

    C. Khor, S. McGinn, C. Fisher, R. Yang, K. Richards, K. Muir, J. Lu

    Nephrology, Royal North Shore Hospital, Sydney, Australia

    *Purpose: The global shortage of organs and the increasing use of marginal kidneys for transplantation necessitates an accurate assessment of deceased donor kidneys. The kidney…
  • 2022 American Transplant Congress

    Lucas Device Assisted Uncontrolled Dcd Kidney Transplantation – A Feasible but Underutilized Option in the United States

    S. Nagaraju, S. Vaishnav, R. Savilla, M. Moore, J. B. Africa

    Renal Transplant, Charleston Area Medical Center, Charleston, WV

    *Purpose: Uncontrolled DCD (uDCD) procurement involves either normo-thermic or hypothermic regional perfusion to reduce ischemic injury. We report a series of successful kidney transplant utilizing…
  • 2022 American Transplant Congress

    COVID-19 Vaccination Induces a Poor Interleukin-21 Memory T-cell Response in Kidney Transplant Recipients

    S. R. Malahe1, Y. den Hartog1, R. de Kuiper1, D. Reijerkerk1, D. Geers2, C. H. GeurtsvanKessel2, M. M. Kho1, R. D. de Vries2, M. E. Reinders1, C. C. Baan1

    1Internal Medicine, Nephrology and Transplantation, Erasmus MC, Rotterdam, Netherlands, 2Viroscience, Erasmus MC, Rotterdam, Netherlands

    *Purpose: COVID-19-related morbidity and mortality is high among kidney patients. Several studies recently suggested low humoral and cellular immune responses after two doses of mRNA-1273…
  • 2022 American Transplant Congress

    Tacrolimus After Rabbit Antithymocyte Globulin And Infliximab Induction Immunosuppression In Kidney Transplantation

    O. Viklicky1, G. Bold2, O. Bestard3, P. Hruba1, I. Zahradka1, N. M. Otto2, M. Stein2, A. Sefrin2, S. Christakoudi4, P. M. Reinke2

    1Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 2Charité, Berlin, Germany, 3Vall d'Hebron, Barcelona, Spain, 4King's College, London, United Kingdom

    *Purpose: Selective targeting of effector/memory T cells as induction immunosuppression has been discussed in kidney transplantation. Confidence-interval-estimation study may help to estimate range of the…
  • 2022 American Transplant Congress

    Ex Vivo End Ischemic Hypothermic Oxygenated Perfusion (hope) Versus Static Cold Storage Prior To Liver Transplantation – Preliminary Results Of The Bridge To Hope Pivotal Multicenter Randomized Controlled Clinical Trial On The Safety And Effectiveness Of The Vitasmart Liver Machine Perfusion System (clinicaltrials.gov: Nct05045794)

    D. J. Reich1, A. Schlegel2, M. Rizzari3, D. Foley4, M. DeVera5, W. Chapman6, G. Roll7, A. Saharia8, C. Quintini9, S. Florman10, S. Merani11, S. Mao12, A. Pinna13, M. Akoad14, C. Kubal15, S. Alexopoulos16, H. Bohorquez17

    1Drexel University, Philadelphia, PA, 2Careggi U, Florence, Italy, 3Henry Ford, Detroit, MI, 4U Wisconsin, Madison, WI, 5Loma Linda, Loma Linda, CA, 6Washington U, Saint Louis, MO, 7UCSF, SF, CA, 8Methodist, Houston, TX, 9Cleveland Clinic, Cleveland, OH, 10Mount Sinai, NY, NY, 11U Nebraska, Omaha, NE, 12Mayo, Jacksonville, FL, 13Cleveland Clinic, Weston, FL, 14Lahey, Burlington, MA, 15Indiana U, Indianapolis, IN, 16Vanderbilt, Nashville, TN, 17Ochsner, New Orleans, LA

    *Purpose: Ex vivo end ischemic hypothermic oxygenated machine perfusion (HOPE) is a simple technique to improve liver transplant (LT) results and the donor shortage. HOPE…
  • 2022 American Transplant Congress

    Clusterin Protects Kidney Transplants from Ischemia-Reperfusion Injury by Modulating Neutrophil Infiltration

    Y. Shim1, R. Fan2, N. Dvorina2, K. McCrae1, B. William2

    1Cardiovascular and Metabolic Sciences, Cleveland Clinic Lerner Research Institute, Cleveland, OH, 2Inflammation and Immunity, Cleveland Clinic Lerner Research Institute, Cleveland, OH

    *Purpose: Ischemia-reperfusion injury (IRI) is inevitable during organ transplantation. Clusterin (CLU) has shown to be protective in IRI. Supplementation of storage solution with recombinant CLU…
  • 2022 American Transplant Congress

    Longitudinal Mortality Risks and Renal Functional Outcomes in Living Kidney Donors

    K. Hotta1, T. Osawa1, I. Yokota2, T. Inao2, T. Tanabe1, N. Iwahara1, N. Shinohara1

    1Urology, Hokkaido University Hospital, Sapporo, Japan, 2Biostatistics, Hokkaido University Graduate School of Medicine, Sapporo, Japan

    *Purpose: Previous studies have suggested that living kidney donors do not have a higher risk of death or end-stage kidney disease (ESKD) than the general…
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