Abstracts Archive - Page 226 of 1683 - ATC Abstracts

2021 American Transplant Congress
Systematic Screening of Kidney Transplant Patients Points Towards Deficits in Neutralizing Antibody Capacity Against Sars-cov-2
V. Wijtvliet¹, K. K. Ariën², J. Mariën², B. Peeters³, R. Hellemans⁴, A. Massart⁴, S. Van Hees¹, P. Moons⁵, H. Theeten⁶, P. Van Damme⁶, H. Goossens⁷, B. Y. De Winter¹, K. J. Ledeganck¹, D. Abramowicz⁴
¹Laboratory of Experimental Medicine and Pediatrics, University of Antwerp, Antwerp, Belgium, ²Department of Biomedical Sciences, Institute of Tropical Medicine and University of Antwerp, Antwerp, Belgium, ³Department of Laboratory Medicine, Antwerp University Hospital, Antwerp, Belgium, ⁴Department of Nephrology and Hypertension, Antwerp University Hospital, Antwerp, Belgium, ⁵Biobank, Antwerp University Hospital, Antwerp, Belgium, ⁶Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium, ⁷Department of Medical Microbiology, Vaccine & Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
*Purpose: The majority of kidney transplant recipients (KTR) is able to develop SARS-CoV-2 antibodies (Abs). Little is known about the virus neutralizing capacity of these…
2021 American Transplant Congress
Development and Durability of Sars-cov-2 Antibodies Among Solid Organ Transplant Recipients
B. Boyarsky, M. Ou, R. Greenberg, M. Krach, R. Wang, T. P. Chiang, W. Werbel, R. Avery, W. Clarke, A. Tobian, A. Massie, D. Segev, J. Garonzik-Wang
Johns Hopkins, Baltimore, MD
*Purpose: The response to SARS-CoV-2 may be blunted in transplant recipients, impacting reinfection risk, treatment selection, and vaccine protocols. We quantified antibody response and durability…
2021 American Transplant Congress
Characterisation of Distinct Graft Infiltrates Following Cellular Therapy in Kidney Transplant Recipients
M. O. Brook¹, P. N. Harden², I. Roberts², W. R. Mulley³, J. Hester¹, M. E. Reinders⁴, F. Issa¹
¹Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, ²Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom, ³Department of Nephrology, Monash Medical Centre, Melbourne, Australia, ⁴Division of Nephrology and Transplant Center, Leiden University Medical Center, Leiden, Netherlands
*Purpose: Cellular therapy is an emerging treatment in the field of clinical transplantation with the potential to improve both short and long-term transplant outcomes. We…
2021 American Transplant Congress
Allocating Kidneys in Optimized Circles: Logistics are More Important Than Distance
R. Saidi, R. Shahbazov, M. Hanlon, M. laftavi
SUNY Upstate, Syracuse, NY
*Purpose: The OPTN recently proposed removing Donation Service Area (DSA) and regional boundaries used in the current kidney allocation system (KAS) and allocate organs within…
2021 American Transplant Congress
Clinical Outcomes and Racial Impact of HLA Matching in the Australian Deceased Donor Kidney Transplantation Program, 2000-2018
M. Gramlick, M. Heer
Department of Surgery, John Hunter Hospital, Newcastle, Australia
*Purpose: The Australian deceased donor (DD) kidney transplant program places a large emphasis on HLA matching despite a known disadvantage to ethnic minority groups. We…
2021 American Transplant Congress
Kidney Transplantation in Very Highly-Sensitized Patients with Maastricht Type III Non-heart-Beating Donors
F. Villanego¹, A. Mazuecos¹, L. Vigara¹, V. Lopez², G. Bernal³, A. Rodriguez-Benot⁴, M. de Gracia⁵, P. Castro⁶, A. Alvarez⁶
¹Department of Nephrology, Hospital Puerta del Mar, Cadiz, Spain, ²Department of Nephrology, Hospital Carlos Haya, Malaga, Spain, ³Department of Nephrology, Hospital Virgen del Rocio, Sevilla, Spain, ⁴Department of Nephrology, Hospital Reina Sofia, Cordoba, Spain, ⁵Department of Nephrology, Hospital Virgen de las Nieves, Granada, Spain, ⁶Andalusian Transplant Coordination, Sevilla, Spain
*Purpose: In 2012, a kidney transplant (KT) program for very highly-sensitized (VHS) patients (PRA ≥ 95%) based on virtual crossmatch began in Andalusia (Spanish region).…
2021 American Transplant Congress
The Association Between Environmental Determinants and High KDRI Organ Offer Acceptance Ratios
A. M. Placona, C. Martinez, M. Stuart
United Network for Organ Sharing, Henrico, VA
*Purpose: Increasing the number of transplants could be realized by increasing high KDRI organ utilization. While the impact of transplant center (TXC) aggressiveness and competition…
2021 American Transplant Congress
Outcomes of Patients Referred for Liver Transplant Evaluation
E. Solomon¹, M. Waykar², K. Robichaux³, J. Buggs⁴, A. Kumar¹, N. Kemmer⁵
¹Morsani College of Medicine, University of South Florida, Tampa, FL, ²Honors College, University of Tampa, Tampa, FL, ³Honors College, University of South Florida, Tampa, FL, ⁴Transplant Surgery, Tampa General Hospital, Tampa, FL, ⁵Transplant Hepatology, Tampa General Hospital, Tampa, FL
*Purpose: National demand for liver transplants is increasing steadily, with 8,896 liver transplants performed in the USA in 2019, a 7.8% increase from 2018. The…
2021 American Transplant Congress
Engineered Human Glomerular Endothelial Cells to Identify Non-hla Antibodies and Decipher Their Pathogenicity After Kidney Transplantation
B. Lamarthée¹, C. Burger¹, C. Leclaire¹, L. Morin¹, F. Terzi¹, C. Tinel¹, D. Anglicheau²
¹Inserm U1151, Necker-Enfants Malades Institute, PARIS, France, ²Necker Hospital, AP-HP, Department of Nephrology and Kidney Transplantation, PARIS, France
*Purpose: In kidney transplantation recipients (KTRs), donor-specific antibodies directed against Human Leucocyte Antigens (HLA-DSA) are thought to drive antibody-mediated rejection (AMR) and poor transplant outcome.…
2021 American Transplant Congress
Status of Kidney Allocation in Liver-kidney Transplants Before and After the UNOS/OPTN Policy
J. Oveyssi, M. Hussain, P. Homkrailas, S. Bunnapradist
Department of Internal Medicine: Division of Transplant Nephrology, UCLA, Los Angeles, CA
*Purpose: On August 10, 2017 the United Network for Organ Sharing (UNOS) enacted policies 9.7 and 8.5G to establish medical criteria for simultaneous liver-kidney (SLK)…