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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Baseline Findings from the UREAACT Trial to Improve Medication Adherence in Youth with Kidney Transplants

    S. Amaral1, P. Kwong2, J. Zhu2, R. George3, N. Rodig4, B. Warady5, J. Smith6, A. Bobrowski7, D. Matossian8, N. Zelikovsky9, L. Schwartz1, P. Reese2, R. Goldfarb Terry1, J. Reason2, A. Chung1, S. Furth1

    1CHOP, Phila, PA, 2UPenn, Phila, PA, 3CHOA, Atlanta, GA, 4Boston Children's, Boston, MA, 5Children's Mercy, Kansas City, MO, 6Seattle Children's, Seattle, WA, 7Cleveland Clinic, Cleveland, OH, 8Lurie Children's, Chicago, IL, 9LaSalle Univ, Phila, PA

    *Purpose: This abstract describes the design and baseline characteristics of participants in the U-REAACT trial, a study to improve medication adherence in youth with kidney…
  • 2022 American Transplant Congress

    Tele-Health Implementation During Covid19 Pandemic in Liver Transplant Population: A Focus on Medication Adherence, Patient Satisfaction, Clinical Outcomes and Possible Cost Impact

    H. Joharji, S. Alghamdi, S. Alqahtani, M. F. Janju, J. Khader, D. Alissa, A. Aljedai, D. Alkortas, K. Bezaizi, D. Broering, A. Ajlan, W. K. Al-Hamoudi, E. Devol, A. Albinmosa, S. Alabbad, Z. Alabdulkarim, A. Zidan, R. Alamawi, E. Alshammari, E. Alharthi, D. Al-Anazi, A. Almalki, M. Alasmari

    Organ Transplant Center of Excellence, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia

    *Purpose: The COVID-19 pandemic affected many aspects of health care, including the provision of care in ambulatory care clinics, necessitating the utilization of telehealth. For…
  • 2022 American Transplant Congress

    Ex Vivo End Ischemic Hypothermic Oxygenated Perfusion (hope) Versus Static Cold Storage Prior To Liver Transplantation – Preliminary Results Of The Bridge To Hope Pivotal Multicenter Randomized Controlled Clinical Trial On The Safety And Effectiveness Of The Vitasmart Liver Machine Perfusion System (clinicaltrials.gov: Nct05045794)

    D. J. Reich1, A. Schlegel2, M. Rizzari3, D. Foley4, M. DeVera5, W. Chapman6, G. Roll7, A. Saharia8, C. Quintini9, S. Florman10, S. Merani11, S. Mao12, A. Pinna13, M. Akoad14, C. Kubal15, S. Alexopoulos16, H. Bohorquez17

    1Drexel University, Philadelphia, PA, 2Careggi U, Florence, Italy, 3Henry Ford, Detroit, MI, 4U Wisconsin, Madison, WI, 5Loma Linda, Loma Linda, CA, 6Washington U, Saint Louis, MO, 7UCSF, SF, CA, 8Methodist, Houston, TX, 9Cleveland Clinic, Cleveland, OH, 10Mount Sinai, NY, NY, 11U Nebraska, Omaha, NE, 12Mayo, Jacksonville, FL, 13Cleveland Clinic, Weston, FL, 14Lahey, Burlington, MA, 15Indiana U, Indianapolis, IN, 16Vanderbilt, Nashville, TN, 17Ochsner, New Orleans, LA

    *Purpose: Ex vivo end ischemic hypothermic oxygenated machine perfusion (HOPE) is a simple technique to improve liver transplant (LT) results and the donor shortage. HOPE…
  • 2022 American Transplant Congress

    p40 Homodimers Stimulate Graft Dendritic Cells to Produce IL-15 Driving Endogenous Donor-Reactive Memory CD8 T Cell Activation within High-Risk Cardiac Allografts

    H. Tsuda1, A. Valujskikh2, R. Fairchild3

    1Inflammation and Immunity, Cleveland Clinic, Cleveland, OH, 2The Cleveland Clinic Fdn, Cleveland, OH, 3Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: Acute allograft injury occurring during the first 1-2 days post-transplant is mediated by graft infiltrating endogenous donor-reactive memory CD8 T cells and requires their…
  • 2022 American Transplant Congress

    Living Related Kidney Donation for Alport Syndrome Spectrum: Long-Term Outcomes

    Y. Caliskan1, A. B. Dirim2, S. Safak2, B. Yelken3, A. Velioglu4, A. Yildiz5, O. A. Oto2, N. Guller2, H. Yazici2, A. Ersoy5, A. Turkmen3, K. L. Lentine1

    1Saint Louis University, Saint Louis, MO, 2Istanbul University, Istanbul, Turkey, 3Koc University Hospital, Istanbul, Turkey, 4Marmara University, Istanbul, Turkey, 5Uludag University, Bursa, Turkey

    *Purpose: Data to guide the evaluation of living related donor (LRD) candidates for kidney transplant recipients with Alport syndrome (AS) spectrum are limited. We examined…
  • 2022 American Transplant Congress

    Deceased Donor Organ Flush with Similar Volumes of HTK and UW at a Single U.S. Organ Procurement Organization: Adult and Pediatric Data

    A. E. Mangus1, C. Kubal2, B. Ekser3, P. Mihaylov4, A. J. Lutz1, J. Fridell5, R. Mangus6

    1Indiana University Purdue University of Indianapolis, Indianapolis, IN, 2Indiana University Hospital, Indianapolis, IN, 3Surgery, Indiana University - Transplant Surgery, Indianapolis, IN, 4Indiana Univ School of Medicine, Indianapolis, IN, 5Indiana University School of Medicine, Indianapolis, IN, 6Indiana University, Indianapolis, IN

    *Purpose: Histidine-tryptophan-ketoglutarate (HTK) and University of Wisconsin (UW) solutions are the two primary solid-organ preservation solutions used in the United States (>95%), but flush volumes…
  • 2022 American Transplant Congress

    Pulmonary Function Tests and Liver Transplantation

    D. Reino1, P. Martinez2, K. Robichaux3, M. Gosselin4, S. Mohammed3, J. Buggs1, A. Kumar5

    1Transplant Surgery, Tampa General Hospital, Tampa, FL, 2University of Miami, Miami, FL, 3University of South Florida, Tampa, FL, 4University of Tampa, Tampa, FL, 5Morsani College of Medicine, University of South Florida, Tampa, FL

    *Purpose: Liver transplant recipients have a high risk of developing postoperative pulmonary complications. Pulmonary function tests (PFTs) are expensive and often incapable of predicting patients…
  • 2022 American Transplant Congress

    Type 1 Natural Killer T-cells: Key Mediators of Ischemia- Reperfusion Injury in Hepatic Steatosis

    J. R. Liggett1, J. Kang1, K. Loh1, K. Oza1, Y. Cui1, D. Kwon2, H. Li3, B. Kallakury2, T. Fishbein1, W. Cui1, K. Khalid1, A. H. Kroemer1

    1MedStar Georgetown Transplant Institute, Washington, DC, 2Pathology, MedStar Georgetown University Hospital, Washington, DC, 3Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC

    *Purpose: Hepatic ischemia-reperfusion injury (IRI) poses a significant risk in liver transplantation and hepatic resection and is further exacerbated by hepatic steatosis. Type 1 Natural…
  • 2022 American Transplant Congress

    Initial Outcome of External Biliary Drainage Tube Insertion in Living Donor Liver Transplantation: Pure Laparoscopic Donor Hepatectomy Dominant Center Experience

    E. Jang1, S. Hong1, S. Hong1, S. Lee1, S. Suh1, E. Han1, Y. Choi2, N. Yi2, K. Lee3, K. Suh4

    1Surgery, Seoul National University Hospital, Seoul, Korea, Republic of, 2Seoul National University Hospital, Seoul, Korea, Republic of, 3Seoul National University, Seoul, Korea, Republic of, 4Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of

    *Purpose: Surgical technique advancements and enhanced perioperative management improved outcome in living donor liver transplantation (LDLT) recipients. However, biliary complication(BC) including biliary leakage(BL) and biliary…
  • 2022 American Transplant Congress

    Results Of The Ctot19 Trial: Infliximab (IFX) Induction Does Not Impact 2-year Outcomes In Deceased Donor Kidney Transplant Recipients

    P. Heeger1, B. Armstrong2, T. Alhamad3, D. Brennan4, J. Bromberg5, S. Bunnapradist6, S. Chandran7, R. Fairchild8, D. Foley9, R. Formica10, I. W. Gibson11, D. Hricik12, K. Kesler2, R. B. Mannon13, M. Menon10, K. Newell14, P. Nickerson11, J. Odim15, E. Poggio8, R. Sung16, R. Shapiro1, K. Tinckam17, F. Vincenti7

    1Mount Sinai, New York, NY, 2Rho, Durham, NC, 3Washington U, Saint Louis, MO, 4Johns Hopkins, Baltimore, MD, 5U Maryland, Baltimore, MD, 6UCLA, Los Angeles, CA, 7UCSF, San Francisco, CA, 8Cleveland Clinic, Cleveland, OH, 9U Wisconsin, Madison, WI, 10Yale, New Haven, CT, 11U Manitoba, Winnipeg, MB, Canada, 12U Hosp Case, Cleveland, OH, 13U Nebraska, Omaha, NE, 14Emory, Atlanta, GA, 15NIAID NIH, Rockville, MD, 16U Michigan, Ann Arbor, MI, 17U Hlth Network, Toronto, ON, Canada

    *Purpose: Ischemia-reperfusion (IR) of a kidney transplant (KTx) up-regulates tumor necrosis factor alpha (TNF) production within the allograft. IR-induced TNF amplifies post-KTx allograft inflammation and…
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