Abstracts Archive - Page 189 of 1683 - ATC Abstracts

2022 American Transplant Congress
Degree of Pre-Liver Transplant Immune Dysfunction Correlates with Post-Transplant Cancer Recurrence
G. S. Prakash¹, G. G. Panayotova¹, S. Simonishvili¹, Y. Qin¹, L. Jin¹, T. Ayorinde¹, L. J. Minze², F. Paterno¹, L. Brown¹, A. Amin¹, D. Liu¹, R. Ghobrial², J. V. Guarrera¹, K. E. Lunsford¹
¹Rutgers New Jersey Medical School, Newark, NJ, ²Houston Methodist Hospital, Houston, TX
*Purpose: Despite stringent selection criteria for liver transplant (LT) in patients with liver-limited malignancy, post-transplant cancer recurrence remains problematic. We have previously identified a pre-LT…
2022 American Transplant Congress
Organs from Donors with Positive SARS-CoV-2 NAT+ Testing: A Report from the Ad Hoc Disease Transmission Advisory Committee
L. Danziger-Isakov¹, J. D. Goldman¹, A. Wooley¹, S. Pouch¹, A. Agarwal¹, G. Berry¹, K. Dunn¹, S. Ho¹, M. Kittleson¹, D. H. Lee¹, D. Levine¹, C. Marboe¹, G. Marklin¹, R. Razonable¹, S. Taimur¹, H. Te¹, C. Fox², C. Jett², S. Booker², D. Klassen², R. LaHoz¹
¹OPTN, Richmond, VA, ²UNOS, Richmond, VA
*Purpose: Decision to transplant organs from SARS-CoV-2 NAT+ donors(N+D) balances risk of donor-derived infection with the scarcity of available organs to meet the needs of…
2022 American Transplant Congress
Implications of Accumulated Cold Time for US Kidney Transplantation Offer Acceptance
M. Barah¹, V. Kilambi², J. Friedewald¹, S. Mehrotra¹
¹Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL, ²Department of Engineering and Applied Sciences, RAND Corporation, Arlington, VA
*Purpose: Reducing discard is a current focus in US transplantation of deceased donor kidneys. One cause for the discards is the avoidance of protracted cold…
2022 American Transplant Congress
Barriers and Facilitators to Care for Patients with Failed Kidney Transplants
A. Huml¹, K. Berg², A. Perzynski², C. Sullivan², A. Sehgal²
¹Department of Kidney Medicine, Cleveland Clinic, Cleveland, OH, ²Population Health Research Institute, The MetroHealth System, Cleveland, OH
*Purpose: To understand the barriers and facilitators to care for patients with failed kidney transplants from the perspective of providers.*Methods: Qualitative study employed focus groups…
2022 American Transplant Congress
Role of Circulating Tumour Cells in the Management of the Liver Transplant Patient with Hepatocellular Carcinoma
F. Villalba¹, F. Alconchel², L. Sáenz³, M. Sánchez-Lorencio¹, D. Ferreras², P. Cascales², F. Sánchez-Bueno², R. Robles², P. Ramírez²
¹IMIB-Virgen de la Arrixaca, Murcia, Spain, ²Surgery and Organ Transplantation, Virgen de la Arrixaca University Hospital (IMIB-Virgen de la Arrixaca), Murcia, Spain, ³Rafael Méndez Hospital, Lorca, Spain
*Purpose: For hepatocellular carcinoma (HCC), liver transplantation (LT) is considered a curative treatment, however, more than 10% of transplant recipients have recurrences within the first…
2022 American Transplant Congress
Induction Immunosuppression Does Not Worsen Tumor Recurrence After Liver Transplantation for T2 Hepatocellular Carcinoma and May Allow for Decreased Mortality
C. Durkin¹, T. Bittermann¹, D. E. Schaubel²
¹Gastroenterology, University of Pennsylvania, Philadelphia, PA, ²Biostatistics, University of Pennsylvania, Philadelphia, PA
*Purpose: Prior studies have suggested that induction therapy leads to worse outcomes after liver transplantation (LT) for hepatocellular carcinoma (HCC). This study evaluated the impact…
2022 American Transplant Congress
Clinical Efficacy of Adjuvant Immunotherapy for Liver Transplant Recipients with Exceeding Japan Criteria of Hepatocellular Carcinoma Using Donor Liver Derived Natural Killer Cells
M. Ohira¹, Y. Imaoka², K. Sato³, K. Imaoka¹, N. Tanimine¹, H. Tahara¹, K. Ide¹, T. Kobayashi¹, Y. Tanaka¹, A. G. Tzakis⁴, S. Nishida⁵, H. Ohdan¹
¹Hiroshima University, Hiroshima, Japan, ²Hiroshima Uni., Hiroshima, Japan, ³Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan, ⁴Digestive Diseases and Surgery Institute, Cleveland Clinic, Cleveland, OH, ⁵Univ of Miami School of Medicine, Valhalla, NY
*Purpose: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and is an indication for liver transplantation (LT). Immunosuppressive regimens currently used after…
2022 American Transplant Congress
Safety and Efficacy of GLP-1 Agonists in Solid Organ Transplant Recipients
E. Heiman, D. Blanco, A. Webb
Pharmacy, Tampa General Hospital, Tampa, FL
*Purpose: Glucagon-like peptide-1 receptor agonists (GLP-1 RA) have been shown to improve glycemic control, obesity, and cardiovascular disease in the general population. The safety and…
2022 American Transplant Congress
The SHELTER Trial of Transplanting Donor Hepatitis C Virus RNA+ Lungs Into Uninfected Recipients
V. Potluri¹, P. Reese¹, S. Prenner¹, H. Mentch¹, D. Goldberg², T. Claridge¹, J. Smith¹, C. Gentile¹, V. Van Deerlin¹, R. Reddy¹, T. Fallah¹, C. Bermudez¹, M. Crespo¹, J. Diamond¹
¹University of Pennsylvania, Philadelphia, PA, ²University of Miami, Miami, FL
*Purpose: The advent of direct acting antiviral therapy has motivated centers to transplant lungs from donors with hepatitis C virus infection (HCV-RNA+) into uninfected recipients.…
2022 American Transplant Congress
Changes in Cold Ischemia Time and Transplantation Practices with the Concentric Model of Kidney Allocation
C. M. Puttarajappa¹, P. Sood¹, A. Tevar¹, V. Gunabushanam¹, S. Hariharan¹, S. Mohan²
¹University of Pittsburgh Medical Center, Pittsburgh, PA, ²Columbia University, New York, NY
*Purpose: Evaluate impact of the new concentric kidney allocation system (KAS250) on kidney utilization, allocation practices and cold ischemia time (CIT).*Methods: Using data from the…