ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Initial Outcome of External Biliary Drainage Tube Insertion in Living Donor Liver Transplantation: Pure Laparoscopic Donor Hepatectomy Dominant Center Experience

    E. Jang1, S. Hong1, S. Hong1, S. Lee1, S. Suh1, E. Han1, Y. Choi2, N. Yi2, K. Lee3, K. Suh4

    1Surgery, Seoul National University Hospital, Seoul, Korea, Republic of, 2Seoul National University Hospital, Seoul, Korea, Republic of, 3Seoul National University, Seoul, Korea, Republic of, 4Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of

    *Purpose: Surgical technique advancements and enhanced perioperative management improved outcome in living donor liver transplantation (LDLT) recipients. However, biliary complication(BC) including biliary leakage(BL) and biliary…
  • 2022 American Transplant Congress

    Axl and MerTK Regulate the Activation of Liver Ischemia Reperfusion Injury by Upregulating Il-13 in Kupffer Cells

    J. Zhang1, M. Ni1, H. Zhang1, R. Busuttil1, J. Kupiec-Weglinski1, X. Wang2, J. Jin3, Y. Zhai1

    1Dumont-UCLA Transplant Center, Los Angeles, CA, 2The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 3Guilin Medical University, Guilin, China

    *Purpose: Ischemia reperfusion injury (IRI) remains an unresolved clinical problem. A sterile inflammatory response drives the disease pathogenesis. Although mechanisms of liver innate immune activation…
  • 2022 American Transplant Congress

    A Patient and Family Decision Support Tool for Kidney Organ Offer Decisions

    C. Schaffhausen1, A. Hart2, S. Chu3, A. K. Israni2, J. Synder1

    1Hennepin Healthcare Research Institute, Minneapolis, MN, 2Hennepin Healthcare / University of Minnesota, Minneapolis, MN, 3University of Minnesota, Saint Paul, MN

    *Purpose: For kidney transplant candidates and their care team, deciding to accept a donor organ with known or potential risk factors can be stressful and…
  • 2022 American Transplant Congress

    Characterization of Acute Kidney Injury in Fatty Liver Ischemia Reperfusion Injury

    Z. P. Rokop, W. Zhang, N. Ghosh, A. Das, N. Biswas, C. Sen, C. Kubal

    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN

    *Purpose: The association between hepatic ischemia reperfusion injury (hIRI) and acute kidney injury (AKI) has been well established. AKI is commonly observed following transplantation of…
  • 2022 American Transplant Congress

    Analysis and Outcomes of Liver Re Transplantation After Initial DCD Liver Transplantation

    A. Kadimella1, J. Eason2, R. Helmick2, J. Vanatta2

    1HPB and Liver Transplantation, AIG Hospitals, Hyderabad, India, 2University of Tennessee/Methodist Transplant Institute, Memphis, TN

    *Purpose: DCD livers were more prone for ischemic cholangiopathy and graft failure than DBD livers due to multi factorial reasons. With all the available data…
  • 2022 American Transplant Congress

    Normal Saline vs Electrolyte-a Use Peri- and Post-Operatively in Adult Kidney Transplant Recipients

    K. R. Szempruch, A. D. Martschenko, H. Arora, R. Isaak, R. Prasad, P. Serrano

    UNC Medical Center, Chapel Hill, NC

    *Purpose: 0.9% normal saline (NS) has been used as the standard fluid replacement in kidney transplant recipients (KTRs) to prevent dehydration and to improve renal…
  • 2022 American Transplant Congress

    Retransplantation in a High-Volume Institution: Historical, Socioeconomic and Survival Trends

    D. von Ahrens, O. Sulimani, M. Holzner, M. Akhtar, S. Florman, A. Arvelakis

    The Mount Sinai Hospital, New York, NY

    *Purpose: Retransplantation for liver allograft failure is a challenge within the field. The evolution of organ allocation policy from Child to MELD in 2002 and…
  • 2022 American Transplant Congress

    Baseline Trends in Tacrolimus Intrapatient Variability in Pediatric and Young Adult Kidney Transplant Recipients

    K. Piburn1, L. Maestretti2, M. V. Patton2, A. M. McGrath2, O. S. Indridason3, A. Chaudhuri1, P. Grimm1, V. Sigurjonsdottir1

    1Pediatric Nephrology, Stanford University, Palo Alto, CA, 2Pediatric Kidney Transplant, Lucile Packard Children's Hospital, Palo Alto, CA, 3Division of Nephrology, Landspitali – the National University Hospital of Iceland, Reykjavik, Iceland

    *Purpose: High tacrolimus intrapatient variability (IPV) is a known risk factor for poor graft outcomes in kidney transplantation. Baseline trends in tacrolimus IPV have not…
  • 2022 American Transplant Congress

    Single Cell RNAseq Analysis of Liver Transplant Rejection Reveals Highly Restricted TCR Clonal Expansion of Tissue-Resident Memory CD8+ T Cells That Persist Despite Corticosteroids and ATG Therapy

    A. L. Peters1, G. Begum1, K. Roskin2, E. Woodle3, D. Hildeman4

    1Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Department of Bioinformatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3Department of Surgery, University of Cincinnati, Cincinnati, OH, 4Department of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    *Purpose: Conventional therapy for liver transplant rejection (corticosteroids and ATG) has remained unchanged for six decades, and is not infrequently met with treatment failure. Here,…
  • 2022 American Transplant Congress

    A Multicenter Randomized Controlled Trial To Compare The Efficacy Of Ex-vivo Machine Perfusion With Static Cold Storage In Human Liver Transplantation: The University Of Maryland Experience

    J. Avruch1, N. Goussous2, S. Malik1, M. Pinedo1, R. Meier1, C. Bhati1, D. Maluf1, R. Barth3, J. Alvarez-Casas1

    1Transplant Surgery, University of Maryland School of Medicine, Baltimore, MD, 2Transplant Surgery, University of California Davis Health, Davis, CA, 3University of Chicago, Chicago, IL

    *Purpose: There is accumulating clinical evidence of the benefit of normothermic ex-vivo machine perfusion (NMP) compared with traditional static cold storage of liver allografts prior…
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