2022 American Transplant Congress
Axl and MerTK Regulate the Activation of Liver Ischemia Reperfusion Injury by Upregulating Il-13 in Kupffer Cells
*Purpose: Ischemia reperfusion injury (IRI) remains an unresolved clinical problem. A sterile inflammatory response drives the disease pathogenesis. Although mechanisms of liver innate immune activation…2022 American Transplant Congress
Estrogen Receptor Beta Deletion is Protective in Renal Ischemia Reperfusion Injury but Pharmacologic Inhibition of Estrogen Receptor Beta is Not
*Purpose: Renal Ischemia Reperfusion Injury (IRI) contributes substantially to delayed graft function (DGF) in kidney transplantation. Prior work by our group has shown lower rates…2022 American Transplant Congress
Characterization of Acute Kidney Injury in Fatty Liver Ischemia Reperfusion Injury
Department of Surgery, Indiana University School of Medicine, Indianapolis, IN
*Purpose: The association between hepatic ischemia reperfusion injury (hIRI) and acute kidney injury (AKI) has been well established. AKI is commonly observed following transplantation of…2022 American Transplant Congress
Retransplantation in a High-Volume Institution: Historical, Socioeconomic and Survival Trends
The Mount Sinai Hospital, New York, NY
*Purpose: Retransplantation for liver allograft failure is a challenge within the field. The evolution of organ allocation policy from Child to MELD in 2002 and…2022 American Transplant Congress
Recurrent Cytomegalovirus and the Role of Secondary Prophylaxis in Heart and Lung Transplant Recipients
*Purpose: This study aimed to describe the incidence of cytomegalovirus (CMV) recurrence in heart and lung transplant recipients and the effect of secondary prophylaxis (SP)…2022 American Transplant Congress
A Successful Expansion of Donor Liver Supply is Feasible with the Selective Use of Older DCD Livers
Baylor Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX
*Purpose: DCD are a key way to expand the donor pool, yet many centers are hesitant about using anything but the most favorable DCD allografts,…2022 American Transplant Congress
Use of Belatacept in Non-Compliant Adolescent Patients
1Nemours Children's Health, Wilmington, DE, 2Nationwide Children's Hospital, Columbus, OH
*Purpose: Adolescents are at high risk for kidney transplant rejection due to non-compliance. While intravenous (IV) maintenance medications are FDA approved for adults, there is…2022 American Transplant Congress
Low-Dose Aspirin is More Critical Than Statins in Preventing Transplant Renal Artery Stenosis
Urology, Henan Provincial People's Hospital, Zhengzhou, China
*Purpose: To explore the clinical value of low-dose aspirin (100mg) and statins (10 ~ 20mg) in the prevention of transplant renal artery stenosis (TRAS).*Methods: A…2022 American Transplant Congress
Bone Fractures Are Not Increased in Older Prior Living Kidney Donors
*Purpose: Living kidney donors were shown to have derangements of bone biomarkers resembling those occurring in early chronic kidney disease within 36 months of donation.…2022 American Transplant Congress
Gsk3beta Regulates the Resolution of Liver Ischemia Reperfusion Injury via MerTK
*Purpose: We have shown previously that glycogen synthase kinase β (Gsk3β) regulates liver inflammatory activation against ischemia/reperfusion injury (IRI). The question of whether it also…
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