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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Liver Transplantation for Metabolic Liver Disease

    J. Wothe, H. Bhatt, D. Vock, S. Schwarzenberg, V. Kirchner, S. Chinnakotla

    University of Minnesota Medical School, Minneapolis, MN

    *Purpose: Liver transplantation (LT) was initially developed as a therapy for liver diseases known to be associated with a high risk of near-term mortality. As…
  • 2022 American Transplant Congress

    Novel Biopsy-Based Clinical Phenotype Clustering to Predict Kidney Transplant Outcomes

    A. Ahmed1, L. Allegretti2, C. Rebello3, B. Kinsella3, K. Guo3, S. Park4, J. Friedewald3

    1Chicago Medical School at Rosalind Franklin University, Chicago, IL, 2University of Wisconsin, Madison, WI, 3Northwestern University, Chicago, IL, 4Transplant Nephrology, Northwestern University, Chicago, IL

    *Purpose: The purpose of this study was to define novel clinical phenotypes based on biopsy results to enhance biomarker discovery.*Methods: Retrospective analysis of kidney biopsy…
  • 2022 American Transplant Congress

    Single Kidney Transplantation Using Pediatric Donor Kidneys: Satisfactory Outcomes but Specific Attentions Needed

    M. Huang, W. Wu, X. Su, J. Li, C. Wu, H. Zhang, Q. Fu, J. Li, S. Wu, Y. Chen, Q. Zhang, L. Liu, C. Wang

    The First Affiliated Hospital Of Sun Yat-sen University, Guangzhou, China

    *Purpose: Utilization of pediatric donor in single kidney transplantation (SKT) are popular and can greatly expand the scarce donor pool, whereas potential risk factors remain…
  • 2022 American Transplant Congress

    Outcome of Pre-Emptive Kidney Transplantation in Children Under 6 Years of Age; A Single Center Experience in Japan

    Y. Aoki1, Y. Hamasaki1, J. Hashimoto1, A. Zaitsu2, M. Kubota1, M. Muramatsu1, T. Kawamura1, S. Shishido2, K. Sakai1

    1Nephrology, Toho University Faculty of Medicine, Tokyo, Japan, 2Pediatric Nephrology, Toho University Faculty of Medicine, Tokyo, Japan

    *Purpose: Kidney transplantation (KT) is the preferred treatment for pediatric end stage renal disease, and pre-emptive kidney transplantation (PEKT) may reduce morbidity and mortality. KT…
  • 2022 American Transplant Congress

    The Role Of Ferroptosis In Modulating Ischemia Reperfusion Injury(IRI) Gene Expression In Marginal Donor Livers(MDLS) Using The Novel Protect Normothermic Perfusion Pump

    M. D. Nazzal1, K. Kurashima2, J. Bettag2, A. Chen2, S. Bruno2, A. Nagarapu2, J. Van Nispen1, J. Krebs2, J. Teckman2, D. Carpenter3, D. Hermelin3, C. Varma1, A. Jain2

    1Surgery, Saint Louis University, Saint Louis, MO, 2Pediatrics, Saint Louis University, Saint Louis, MO, 3Pathology, Saint Louis University, Saint Louis, MO

    *Purpose: Severe IRI can impair liver allograft when using MDLs and accounts for high discard rates. We tested iron chelators to reduce ferroptosis and IRI.…
  • 2022 American Transplant Congress

    Outcomes of Kidney Transplantation from a Male Donor with a Highly Elevated Prostate Specific Antigen Level (PSA) in Female Recipients

    S. K. Patel, E. Siskind, M. Jaleco, S. Shah, A. Adekile, S. Nijim, M. Laftavi

    Center for Transplantation, University Medical Center of Southern Nevada, Las Vegas, NV

    *Purpose: Donor derived malignancy is a contraindication for kidney transplantation. Published literature is devoid of instances of utilization of organs from donors with high PSA…
  • 2022 American Transplant Congress

    Early Post-Operative Thrombotic Microangiopathy in Deceased Donor Kidney Transplant: A Retrospective Case Series

    R. Seneriz1, A. Mattiazzi1, G. Guerra1, T. Harrington2, M. Velasquez3

    1Miami Transplant Institute, Miami, FL, 2University of Miami, Miami, FL, 3Jackson Memorial Hospital, Miami, FL

    *Purpose: Transplant associated thrombotic microangiopathy (TA-TMA) is characterized by endothelial injury along with thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and kidney graft dysfunction. It can be…
  • 2022 American Transplant Congress

    A New Chapter In An Evolving Pandemic: Successful Pediatric Liver Transplantation With Covid+ Donors

    M. B. Goss1, F. Munoz2, E. A. Moulton3, S. Pouch4, S. Koohmaraie5, N. Moreno1, J. Goss3, N. Galvan3

    1McGovern Medical School, Houston, TX, 2Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 3Baylor College of Medicine, Houston, TX, 4Emory University School of Medicine, Decatur, GA, 5Texas Children's Hospital, Houston, TX

    *Purpose: We report the first two pediatric liver transplants utilizing allografts from COVID+ donors, infected at time of organ procurement, demonstrating a pivotal step toward…
  • 2022 American Transplant Congress

    Perfusate Il-6 Levels During Liver Nmp Are Predictive For Hemodynamic Response And Catecholamine Demand After Reperfusion In The Recipient

    A. Weissenbacher1, S. Mathis2, B. Cardini1, C. Bogensperger1, G. Putzer2, L. Gasteiger2, T. Resch1, R. Oberhuber1, D. Öfner1, T. Hell3, J. Martini2, S. Schneeberger1

    1Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria, 2Department of Anaesthesiology and Critical Care Medicine, Medical University of Innsbruck, Innsbruck, Austria, 3Department of Mathematics, Faculty of Mathematics, Computer Science and Physics, University of Innsbruck, Innsbruck, Austria

    *Purpose: Normothermic liver preservation (NMP) has become a clinical routine at several transplant centres. Reperfusion-syndrome occurs less often in recipients of NMP-livers compared to cold…
  • 2022 American Transplant Congress

    Rapid Formalin-Fixed Deceased Donor Kidney Biopsy Protocol – A Proof Of Concept

    M. R. Marvin1, G. Chen2, A. Kotru1, C. Koo1, P. Sanghi3, M. Moritz4, J. Clarke4, R. Hasz4

    1Transplant, Geisinger Medical Center, Danville, PA, 2Pathology, Geisinger Medical Center, Danville, PA, 3Transplant Nephrology, Geisinger Medical Center, Danville, PA, 4Gift of Life Donor Program, Philadelphia, PA

    *Purpose: Reducing kidney discard is a major priority for the transplant community. While frozen section biopsies are the current standard, they are fraught with technical…
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