ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    T and B Cell Response to 3 Dose Covid Vaccine Series for Kidney Transplant Patients on Belatacept

    J. Christensen1, I. Yakubu2, D. Kumar1, D. Cornett3, M. A. Miller3, M. Altrich3, L. Flebbe-Rehwaldt3, R. Thompson1, G. Gupta1

    1Internal Medicine, Transplant Nephrology, VCUHealth, Richmond, VA, 2Pharmacy, VCUHealth, Richmond, VA, 3Eurofins Viracor, Lee's Summit, MO

    *Purpose: Data shows COVID vaccine response after 2 doses in patients on Belatacept immunosuppression (IS) is low, with reported rates of seroconversion (as measured by…
  • 2022 American Transplant Congress

    The Impact of New-Onset Diabetes After Transplantation on Survival and Major Cardiovascular Events in Korean Kidney Transplantation Recipients

    E. Kang1, J. Lee2, D. Kang3, Y. Jang4, S. Park5, Y. Kim4, D. Kim4, K. Joo4, Y. Kim4, M. Park6, Y. Lim7, H. Lee4

    1Ewha Womans University Seoul Hospital, Seoul, Korea, Republic of, 2Dongguk University Ilsan Hospital, Goyang, Korea, Republic of, 3Chung-Ang University, Seoul, Korea, Republic of, 4Seoul National University Hospital, Seoul, Korea, Republic of, 5Seoul National University College of Medicine, Seoul, Korea, Republic of, 6Informations and Statistics, Chungnam National University, Daejeon, Korea, Republic of, 7Applied Statistics, Chung-Ang University, Seoul, Korea, Republic of

    *Purpose: New-onset diabetes after transplantation (NODAT) is a frequent complication in kidney transplant (KT) recipients with unfavorable outcomes, although a nationwide study on epidemiology and…
  • 2022 American Transplant Congress

    Histologic Predictors of Graft Loss in Early Clinically Indicated Biopsies After Kidney Transplantation

    M. Ajaimy1, V. Hemmige2, L. E. Liriano-Ward3, Y. Azzi1, S. Kapoor4, P. Loarte1, C. Pynadath5, A. Colovai1, E. Akalin6

    1Einstein-Montefiore Transplant Center, Bronx, NY, 2Montefiore Medical Center, Bronx, NY, 3Transplant, Montefiore Medical Center, Bronx, NY, 4Montefiore Medical Center, New York, NY, 5Einstein-Montefiore Transplant Center, Scarsdale, NY, 6Albert Einstein College of Medicine, Montefiore Medical Ctr, Bronx, NY

    *Purpose: We aimed to investigate histopathological predictors of graft lost in patients who underwent clinically indicated biopsies for worsening kidney function and/or proteinuria within 3…
  • 2022 American Transplant Congress

    Reflections on the Most Prolific United States Kidney Transplant Surgeon: A Career That Helped Define the Standard of Transplant Care

    C. Killian1, R. Reed2, P. MacLennan1, D. Anderson1, R. Cannon1, B. Orandi1, P. Porrett1, S. Sheikh1, C. Young1, M. J. Hanaway1, J. Locke1

    1University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Irondale, AL

    *Purpose: The standard of care in kidney transplantation has evolved with advances in immunosuppressive therapy. Few transplant surgeons experienced the realization of these advances firsthand.…
  • 2022 American Transplant Congress

    An Immune-Modulatory Strategy to Mitigate Hepatic Ischemia Reperfusion Injury in a Murine Model

    S. Duarte, A. Kobayashi, V. Boominathan, A. Kwiatkowski, J. Simonovich, A. Wanchoo, G. Hudalla, B. Keselowsky, A. Zarrinpar

    University of Florida, Gainesville, FL

    *Purpose: Hepatic ischemia/reperfusion injury (IRI) is the leading cause of early graft dysfunction and contributes to the shortage of donor liver grafts. However, despite its…
  • 2022 American Transplant Congress

    National Attitudes Towards Early Liver Transplantation for Alcoholic Liver Disease

    J. Mitchell1, K. Nijhar1, K. Herrick-Reynolds2, H. Sung1, P. Chen1, D. L. Segev1, E. King1, A. Cameron1

    1Department Of Surgery, Johns Hopkins University, Baltimore, MD, 2Department Of Surgery, Walter Reed National Military Medical Center, Bethesda, MD

    *Purpose: Pre-transplant abstinence requirements, notably the 6-month sobriety guideline, limit access to liver transplant for patients with severe alcoholic hepatitis (SAH). This study examines the…
  • 2022 American Transplant Congress

    Recipient Treatment with Anti-CD122 mAb Prolongs Kidney Allograft Survival During Antibody-Mediated Rejection without Impacting NK Cell Activation within the Graft

    D. Okada, S. Miyairi, N. Dvorina, K. S. Keslar, A. Valujskikh, W. Baldwin, R. Fairchild

    Cleveland Clinic, Cleveland, OH

    *Purpose: Dysregulated donor-specific antibody (DSA) responses are induced in B6.CCR5-/- mice transplanted with complete MHC mismatched kidney allografts and are required for rejection of the…
  • 2022 American Transplant Congress

    Covid19 in Pediatric Kidney Transplant Recipients: Incidence, Outcomes, and Response to Vaccine

    A. Moudgil, K. Sgambat, Y. Shi, M. Meyers, C. Petyak, L. Midgley

    Nephrology, Children's National Med. Ctr., Washington, DC

    *Purpose: At the onset of pandemic, no information was available on response of pediatric kidney transplant (PKTX) recipients to COVID19. When COVID19 vaccines became available,…
  • 2022 American Transplant Congress

    Ultrasound Assessing Donor Kidney Quality in Deceased Donor Kidney Transplantation

    S. Yun1, K. Lee1, S. Park2, J. Park1

    1Surgery, Samsung Medical Center, Seoul, Korea, Republic of, 2Radiology and Center for Imaging Science, Samsung Medical Center, Seoul, Korea, Republic of

    *Purpose: We evaluated the role of functional kidney volume using donor kidney ultrasound (US) alone or in combination with other donor factors and parameters appropriate…
  • 2022 American Transplant Congress

    Results Of The Ctot19 Trial: Infliximab (IFX) Induction Does Not Impact 2-year Outcomes In Deceased Donor Kidney Transplant Recipients

    P. Heeger1, B. Armstrong2, T. Alhamad3, D. Brennan4, J. Bromberg5, S. Bunnapradist6, S. Chandran7, R. Fairchild8, D. Foley9, R. Formica10, I. W. Gibson11, D. Hricik12, K. Kesler2, R. B. Mannon13, M. Menon10, K. Newell14, P. Nickerson11, J. Odim15, E. Poggio8, R. Sung16, R. Shapiro1, K. Tinckam17, F. Vincenti7

    1Mount Sinai, New York, NY, 2Rho, Durham, NC, 3Washington U, Saint Louis, MO, 4Johns Hopkins, Baltimore, MD, 5U Maryland, Baltimore, MD, 6UCLA, Los Angeles, CA, 7UCSF, San Francisco, CA, 8Cleveland Clinic, Cleveland, OH, 9U Wisconsin, Madison, WI, 10Yale, New Haven, CT, 11U Manitoba, Winnipeg, MB, Canada, 12U Hosp Case, Cleveland, OH, 13U Nebraska, Omaha, NE, 14Emory, Atlanta, GA, 15NIAID NIH, Rockville, MD, 16U Michigan, Ann Arbor, MI, 17U Hlth Network, Toronto, ON, Canada

    *Purpose: Ischemia-reperfusion (IR) of a kidney transplant (KTx) up-regulates tumor necrosis factor alpha (TNF) production within the allograft. IR-induced TNF amplifies post-KTx allograft inflammation and…
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