Abstracts Archive - Page 181 of 1683 - ATC Abstracts

2022 American Transplant Congress
Efficacy of a Multispecialty, Multidisciplinary Strategy to Improve the Level of Awareness and Control of Cardiovascular Risk Factors After Liver Transplantation
G. Crespo, L. Sastre, R. García, C. Viñals, A. J. Amor, G. Yago, A. Hervas, L. Sánchez, J. Trabal, J. Molero, L. Escude, G. Pagano, M. Blasco, R. Gilabert, P. Ruiz, J. Colmenero, M. Navasa, E. Ortega
Hospital Clinic, Barcelona, Spain
*Purpose: Although liver transplant (LT) recipients are at high cardiovascular risk, the management of cardiovascular risk factors (CVRF) after LT is far from optimal. We…
2022 American Transplant Congress
Functional Recellularized Patient Derived Endothelium; A Human Vascular Graft Approach
H. Tejeda Mora¹, J. Willemse², Y. den Hartog¹, I. Schurink², M. M. Verstegen², J. de Jonge², R. C. Minnee², M. W. van den Hoogen², C. C. Baan¹, L. J. van der Laan², M. J. Hoogduijn¹
¹Transplant Institute - Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands, ²Transplant Institute - Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands
*Purpose: In transplantation, the endothelial lining is the first barrier between the donor organ and recipient immune system. Damaged endothelium exposes extracellular matrix (ECM) molecules…
2022 American Transplant Congress
A Third Dose of SARS-CoV-2 Vaccine Increases Neutralizing Antibodies Against Variants of Concern in Solid Organ Transplant Recipients
A. H. Karaba¹, X. Zhu¹, T. Ling¹, K. H. Wang¹, A. G. Rittenhouse¹, O. Akinde¹, Y. Eby¹, J. E. Ruff¹, J. N. Blankson¹, A. T. Abedon¹, J. L. Alejo¹, A. L. Cox¹, J. R. Bailey¹, E. A. Thompson¹, S. L. Klein¹, D. S. Warren¹, J. M. Garonzik-Wang², B. J. Boyarsky¹, I. Sitaras¹, A. Pekosz¹, D. L. Segev¹, A. A. Tobian¹, W. A. Werbel¹
¹Johns Hopkins University, Baltimore, MD, ²University of Wisconsin School of Medicine and Health, Madison, WI
*Purpose: Vaccine-induced SARS-CoV-2 antibody responses are attenuated in solid organ transplant recipients (SOTRs) and breakthrough infections are more common. Additional SARS-CoV-2 vaccine doses increase anti-spike…
2022 American Transplant Congress
Living Related Kidney Donation for Alport Syndrome Spectrum: Long-Term Outcomes
Y. Caliskan¹, A. B. Dirim², S. Safak², B. Yelken³, A. Velioglu⁴, A. Yildiz⁵, O. A. Oto², N. Guller², H. Yazici², A. Ersoy⁵, A. Turkmen³, K. L. Lentine¹
¹Saint Louis University, Saint Louis, MO, ²Istanbul University, Istanbul, Turkey, ³Koc University Hospital, Istanbul, Turkey, ⁴Marmara University, Istanbul, Turkey, ⁵Uludag University, Bursa, Turkey
*Purpose: Data to guide the evaluation of living related donor (LRD) candidates for kidney transplant recipients with Alport syndrome (AS) spectrum are limited. We examined…
2022 American Transplant Congress
Single Cell RNAseq Analysis of Liver Transplant Rejection Reveals Highly Restricted TCR Clonal Expansion of Tissue-Resident Memory CD8⁺ T Cells That Persist Despite Corticosteroids and ATG Therapy
A. L. Peters¹, G. Begum¹, K. Roskin², E. Woodle³, D. Hildeman⁴
¹Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Department of Bioinformatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Department of Surgery, University of Cincinnati, Cincinnati, OH, ⁴Department of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
*Purpose: Conventional therapy for liver transplant rejection (corticosteroids and ATG) has remained unchanged for six decades, and is not infrequently met with treatment failure. Here,…
2022 American Transplant Congress
Liver Transplantation for Primary Sclerosing Cholangitis (psc): Experience from the Last Three Decades
J. Zhu¹, D. Lim¹, L. James¹, E. Yoshida², K. Peltekian¹
¹Medicine, Dalhousie University, Halifax, NS, Canada, ²Medicine, University of British Columbia, Vancouver, BC, Canada
*Purpose: In liver transplantation (LT) for PSC, pre-transplant colectomy may lower the risk of PSC recurrence (rPSC), and well-controlled or lack of IBD may protect…
2022 American Transplant Congress
Understanding the Impact of Financial Obstacles and Reimbursement for Lost Wages on the Decision-Making Process for Living Organ Donation
R. J. Mandell¹, A. R. Smith¹, K. A. Gifford², B. A. Hong³, N. P. Goodrich¹, A. K. Mathur⁴, M. A. Fava¹, A. O. Ojo⁵, R. M. Merion¹
¹Arbor Research Collaborative for Health, Ann Arbor, MI, ²American Society of Transplant Surgeons, Arlington, VA, ³Washington University in St. Louis, St. Louis, MO, ⁴Mayo Clinic in Arizona, Phoenix, AZ, ⁵University of Kansas Medical Center, Kansas City, KS
*Purpose: This study examined the impact of financial obstacles (e.g., lost wages, travel, and dependent care expenses) on the decision to initiate an evaluation for…
2022 American Transplant Congress
Towards Bionic Organs: Biocompatibility Of Newly Developed Porcine Decm-based Hydrogels.
M. Rachalewski, M. Klak, D. Ujazdowska, P. Cywoniuk, T. Dobrzanski, G. Tymicki, K. Kosowska, T. Bryniarski, A. Berman, M. Wszola
Foundation of Research and Science Development, Warsaw, Poland
*Purpose: There is a growing interest in fabrication of bioinks which on one hand biocompatible and on the other hand possess mechanical properties which would…
2022 American Transplant Congress
p40 Homodimers Stimulate Graft Dendritic Cells to Produce IL-15 Driving Endogenous Donor-Reactive Memory CD8 T Cell Activation within High-Risk Cardiac Allografts
H. Tsuda¹, A. Valujskikh², R. Fairchild³
¹Inflammation and Immunity, Cleveland Clinic, Cleveland, OH, ²The Cleveland Clinic Fdn, Cleveland, OH, ³Cleveland Clinic Foundation, Cleveland, OH
*Purpose: Acute allograft injury occurring during the first 1-2 days post-transplant is mediated by graft infiltrating endogenous donor-reactive memory CD8 T cells and requires their…
2022 American Transplant Congress
Dialysis Patient Perspectives on Obesity as a Barrier to Kidney Transplantation
S. S. Hingorany, A. Klassen, B. Milliron, J. Sweeting, J. Lee, R. HaileSelasse, B. Gunen, M. N. Harhay
Drexel University, Philadelphia, PA
*Purpose: Although obesity is a known barrier to kidney transplantation (KT) and associated with delayed graft function and graft loss, guidance is lacking on optimal…