ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Inhibition of ITGB5 Protects Hepatocytes from Ischemia Reperfusion Injury

    M. Dogan1, S. Naik1, C. Watkins1, A. Bajwa1, V. Mas2, J. Eason3, C. Kuscu1, C. Kuscu1

    1Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, 2Surgery, University of Maryland, Baltimore, MD, 3University of Tennessee/Methodist Transplant Institute, Memphis, TN

    *Purpose: Liver transplantation is the best treatment option for patients with end-stage liver disease (ESLD). Despite the increasing interest to the machine reperfusion, cold preservation…
  • 2022 American Transplant Congress

    Impact of Delayed Graft Function in Donation After Circulatory Death Kidney Transplantation

    J. Mello Offerni1, H. Brar1, D. Lee1, M. Levine2, M. Mandurah1, S. Rim1, A. Sener1, P. Luke1

    1Urology, Western University, London, ON, Canada, 2Division of Urology, Department of Surgery, University of Alberta, Edmonton, AB, Canada

    *Purpose: Donation after circulatory death (DCD) has been associated with higher rates of delayed graft function (DGF) when compared to donation after brain death (DBD).…
  • 2022 American Transplant Congress

    Gene Expression Changes Including Long Non-Coding RNAs in Human Hepatic Ischemia Reperfusion Injury

    C. Kuscu1, S. Naik1, C. Eymard2, H. Ingram1, A. Bajwa1, D. Maluf3, V. Mas4, J. Eason5, C. Kuscu1

    1Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, 2James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, 3Surgery, University of Maryland, Baltimore, MD, 4University of Maryland, Baltimore, MD, 5University of Tennessee/Methodist Transplant Institute, Memphis, TN

    *Purpose: Ischemia reperfusion injury (IRI) is still one of the major problems in liver transplantation affecting long term outcomes. This study is sought out to…
  • 2022 American Transplant Congress

    Genotype and Phenotype Analysis and the Transplantation Strategy in Children with Uremia Caused by Nephronophthisis

    J. Li, H. Zhang, X. Su, J. Li, S. Wu, W. Wu, L. Ling, Q. Fu, C. Wu, L. Liu, C. Wang

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

    *Purpose: Nephronophthisis- related ciliopathies(NPHP- RC), as an important cause of children's end-stage renal disease(ESRD), has strong genotype and phenotype heterogeneity, and the transplantation strategy of…
  • 2022 American Transplant Congress

    Urine-based Assay For Detection Of Acute Rejection In Pediatric Kidney Transplant Recipients

    C. Crane1, K. Zeeb2, E. Phebus2, C. Benavides2, W. Wong3, E. Ingulli2

    1UCSD/Rady Children's Hospital, San Diego, CA, 2UCSD Rady Children's Hospital, San Diego, CA, 3Massachusetts General Brigham, Boston, MA

    *Purpose: Biomarkers such as donor-derived cell free DNA (cfDNA) and gene expression profiling are utilized in adult transplant patients (pts), but these tests lack sensitivity…
  • 2022 American Transplant Congress

    National Survey of Solid Organ Transplant Pharmacist Training and Early Career Research Success

    A. Lichvar1, M. Chandran2, M. Durst3, S. Fredrick4, D. Pierce5, H. Sweiss6, A. Szczepanik7, J. Melaragno8

    1UC San Diego Health, La Jolla, CA, 2Pharmacy, UNC Hospitals, Chapel Hill, NC, 3Aurora St. Luke's Medical Center, Waukesha, WI, 4University of Rochester Medical Center, Buffalo, NY, 5University of Illinois at Chicago, Chicago, IL, 6University Health - University Hospital, San Antonio, TX, 7University of Maryland, Baltimore, MD, 8University of Rochester, Rochester, NY

    *Purpose: The purpose of this study is to assess the incidence of early career publications of solid organ transplant (SOT) clinical pharmacists and to describe…
  • 2022 American Transplant Congress

    Nebulized Mitochondria Localize to Transplanted Allografts and Improve Outcomes Following Lung Transplantation

    D. Nord1, Z. Tu2, L. Langerude1, A. McQuiston1, J. Kwon3, S. Nadig4, T. Machuca5, C. Atkinson1

    1Pulmonary Medicine, University of Florida, Gainesville, FL, 2University of Florida, Gaineville, FL, 3MUSC College of Medicine, Charleston, SC, 4Northwestern University, Charleston, SC, 5Department of Surgery, University of Florida, Gainesville, FL

    *Purpose: Mitochondrial transplantation therapy is an innovative strategy for the treatment of mitochondrial dysfunction. The approach has shown efficacy in the treatment of cardiac ischemic…
  • 2022 American Transplant Congress

    Frequency of Cervical Cancer Screening in Solid Organ Transplant Recipients

    C. Papastamelos1, K. Dokus2, M. Laryea3

    1Internal Medicine, University of Rochester Medical Center, Rochester, NY, 2Transplant Division, University of Rochester Medical Center, Rochester, NY, 3Gastroenterology, University of Rochester Medical Center, Rochester, NY

    *Purpose: Human papillomavirus-related anogenital malignancies disproportionately affect solid organ transplant recipients (SOTR) compared to the general population. Proposed cervical Pap testing intervals for SOTR differ…
  • 2022 American Transplant Congress

    Benefit of Kidney Transplantation for Post Lung Transplantation Renal Failure: Need for Priority Allocation

    S. Karhadkar1, A. Gregor1, K. Jonathan1, J. Dawes1, A. Diamond2, K. Wirshup1, A. DiCarlo1

    1Temple University Hospital, Philadelphia, PA, 2-, Garnet Valley, PA

    *Purpose: Nephrotoxicity is a major side effect of thoracic transplantation. Many patients will eventually require renal transplantation (KAL) to manage their developing ESRD. Recently, simultaneous…
  • 2022 American Transplant Congress

    Efficacy and Safety of Denosumab on Osteoporosis in Kidney Transplant Recipients

    W. Park, J. Kwon, J. Lim, Y. Kim, J. Paek, K. Jin, S. Han

    Division of Nephrology, Department of Internal Medicine, Keimyung University School of Medicine, Keimyung University Dongsan Hospital, Daegu, Korea, Republic of

    *Purpose: The use of immunosuppressive agents, especially glucocorticoids, are associated with increased risks of bone loss in kidney transplant recipients (KTRs). Denosumab, a potent antiresorptive…
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