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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Novel Biopsy-Based Clinical Phenotype Clustering to Predict Kidney Transplant Outcomes

    A. Ahmed1, L. Allegretti2, C. Rebello3, B. Kinsella3, K. Guo3, S. Park4, J. Friedewald3

    1Chicago Medical School at Rosalind Franklin University, Chicago, IL, 2University of Wisconsin, Madison, WI, 3Northwestern University, Chicago, IL, 4Transplant Nephrology, Northwestern University, Chicago, IL

    *Purpose: The purpose of this study was to define novel clinical phenotypes based on biopsy results to enhance biomarker discovery.*Methods: Retrospective analysis of kidney biopsy…
  • 2022 American Transplant Congress

    Impact of Cold Ischemia Times on 1 Year Kidney Transplant Outcomes

    T. Fletchinger, L. Burdine

    Department of Surgery, University of Arkansas for Medical Sciences, Little Rock, AR

    *Purpose: Recent organ allocation changes have increased travel and subsequent cold ischemia times (CIT) of kidney allografts. We sought to investigate the impact of prolonged…
  • 2022 American Transplant Congress

    A Randomized Phase 2 Study Of Mau868 Vs Placebo To Treat Bk Viremia In Kidney Transplant Recipients

    S. Jordan1, A. P. Limaye2, B. Fischbach3, P. Sood4, S. Collette5, L. Gasink6, M. W. Fordyce7, C. J. Lin7, M. Hodges6, D. C. Brennan8

    1Cedars-Sinai Medical Center, Los Angeles, CA, 2University of Washington, Seattle, WA, 3Dallas Nephrology Associates, Inc, Dallas, TX, 4University of Pittsburgh Medical Center, Pittsburgh, PA, 5Hôpital Maisonneuve-Rosemont, Montréal, QC, Canada, 6previous employee/consultant for Amplyx Pharmaceuticals, San Diego, CA, 7Vera Therapeutics, Inc, Brisbane, CA, 8Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: To assess the safety and efficacy of MAU868, a BK virus-specific monoclonal antibody, in adult kidney transplant recipients with BK viremia.*Methods: This is a…
  • 2022 American Transplant Congress

    Evaluation of Donor Exclusion Criteria in Living Donor Liver Transplantation: A Single-Center Experience

    D. Daskalaki, M. E. Akoad, J. Kim, C. J. Simon, Y. Cheah

    Hepatobiliary Surgery and Liver Transplantation, Lahey Hospital and Medical Center, Burlington, MA

    *Purpose: Liver donation is fundamental in increasing the pool of available grafts. Careful evaluation of each donor ensures the best outcomes for the recipient and…
  • 2022 American Transplant Congress

    Recipient Treatment with Anti-CD122 mAb Prolongs Kidney Allograft Survival During Antibody-Mediated Rejection without Impacting NK Cell Activation within the Graft

    D. Okada, S. Miyairi, N. Dvorina, K. S. Keslar, A. Valujskikh, W. Baldwin, R. Fairchild

    Cleveland Clinic, Cleveland, OH

    *Purpose: Dysregulated donor-specific antibody (DSA) responses are induced in B6.CCR5-/- mice transplanted with complete MHC mismatched kidney allografts and are required for rejection of the…
  • 2022 American Transplant Congress

    Impact of Belatacept Conversion on Renal Function and Donor Specific Antibodies in Renal Transplant Recipients

    E. R. Brown, K. Cunningham, K. Paplaczyk, C. Dagostino, C. Kane, A. Shetty

    Northwestern Memorial Hospital, Chicago, IL

    *Purpose: Although associated with nephrotoxicity, calcineurin inhibitors (CNI) have historically been the cornerstone of immunosuppression. Belatacept, a co-stimulation blocker, is FDA-approved for de novo use…
  • 2022 American Transplant Congress

    Baseline Findings from the UREAACT Trial to Improve Medication Adherence in Youth with Kidney Transplants

    S. Amaral1, P. Kwong2, J. Zhu2, R. George3, N. Rodig4, B. Warady5, J. Smith6, A. Bobrowski7, D. Matossian8, N. Zelikovsky9, L. Schwartz1, P. Reese2, R. Goldfarb Terry1, J. Reason2, A. Chung1, S. Furth1

    1CHOP, Phila, PA, 2UPenn, Phila, PA, 3CHOA, Atlanta, GA, 4Boston Children's, Boston, MA, 5Children's Mercy, Kansas City, MO, 6Seattle Children's, Seattle, WA, 7Cleveland Clinic, Cleveland, OH, 8Lurie Children's, Chicago, IL, 9LaSalle Univ, Phila, PA

    *Purpose: This abstract describes the design and baseline characteristics of participants in the U-REAACT trial, a study to improve medication adherence in youth with kidney…
  • 2022 American Transplant Congress

    Team Decision-Making in Liver Transplant Evaluation: A Multi-Center Ethnographic Observation Study

    C. N. Sidoti, H. C. Sung, D. L. Segev, M. L. Levan, T. S. Purnell, A. T. Strauss

    Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: Transplant providers are tasked with making ethically complex and high-stakes decisions of determining a patient’s candidacy for liver transplantation within a multi-disciplinary team. We…
  • 2022 American Transplant Congress

    Variation in Donor Liver Rejection Rates for Donor Quality Among US Transplant Centers

    M. Anderson1, T. Gilbert2, M. Englesbe1, S. Waits1

    1Michigan Medicine Transplant Center, Ann Arbor, MI, 2University of Michigan Medical School, Ann Arbor, MI

    *Purpose: Optimal utilization of all viable donor livers is a public health imperative. As no standardized criteria exist for assessment of donor quality, differential utilization…
  • 2022 American Transplant Congress

    Renal Transplantation and Statins Effects on Dyslipidemia in Renal Transplant Recipients

    Z. Arabi, A. Alghamdi, A. Alnasrullah, A. R. Altheaby, M. Tawhari, N. Alnazari

    KAMC, Riyadh, Saudi Arabia

    *Purpose: to review the effect of renal transplantation and adding of statins on dyslipidemia in renal transplant recipients.*Methods: A single center experience retrospective study of…
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