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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Pretransplant Recipient TNFR2+T Regulatory Cell Frequency Predicts Long-Term Outcomes After Kidney Transplantation

    A. Kouyoumdjian, N. Saberi, S. Negi, J. Tchervenkov, S. Paraskevas

    McGill University Health Centre, Montreal, QC, Canada

    *Purpose: Pre-transplant indices capable of predicting long-term renal allograft function could improve graft allocation strategies. We previously associated pretransplant frequency of Tumor Necrosis Factor Receptor…
  • 2022 American Transplant Congress

    Detection of CMV Mediated Sub-Clinical Rejection by Urine Biomarkers

    S. Ghosh1, R. Sarwal1, C. Mark1, E. Reed2, J. Shoji3, S. Bunnapradist2, T. Sigdel3, M. Sarwal3

    1Nephrosant Inc, San Francisco, CA, 2UCLA, Los Angeles, CA, 3UCSF, San Francisco, CA

    *Purpose: Research on early detection of Cytomegalovirus (CMV) mediated sub-clinical rejection (sAR) is in its nascence. This study explores the efficacy of urine-based biomarkers for…
  • 2022 American Transplant Congress

    130 Totally Robotic Donor Hepatectomy: Reproducibility Of A Standardized Technique Across 2 Specialized Centers

    Y. Cheah1, H. Yang2, C. J. Simon1, J. Kim3, M. Akoad3, G. Choi2

    1Roger L Jenkins Transplant Institute, Lahey Hospital & Medical Center, Burlington, MA, 2Division of HPB Surgery, Yonsei University College of Medicine, Seoul, Korea, Republic of, 3Lahey Hospital & Medical Center, Burlington, MA

    *Purpose: Robotic surgery is emerging as a feasible though complex technique to enable minimally-invasive donor hepatectomy.*Methods: First multicenter prospective study on 130 consecutive totally robotic…
  • 2022 American Transplant Congress

    Incidence of Dapsone-Induced Methemoglobinemia in Solid Organ Transplant Recipients

    D. Quan1, R. Gordon1, J. Lee1, D. Khoshabafard2, A. Han1

    1Pharmacy, UCSF Medical Center, San Francisco, CA, 2Clinical Phamacy, UCSF School of Pharmacy, San Francisco, CA

    *Purpose: The purpose of this study was to determine the incidence of dapsone-induced methemoglobinemia in solid organ transplant recipients.*Methods: This was a single-center retrospective cohort…
  • 2022 American Transplant Congress

    Antibody Response to 3-Dose SARS-CoV-2 mRNA Vaccination in Pediatric Solid Organ Transplant Recipients

    C. X. Qin1, S. R. Auerbach2, O. Charnaya1, L. A. Danziger-Isakov3, N. H. Ebel4, A. G. Feldman2, E. K. Hsu5, J. McAteer1, S. Mohammad6, E. R. Perito7, A. M. Thomas1, T. P. Chiang1, J. M. Garonzik-Wang1, D. L. Segev1, D. B. Mogul1

    1Johns Hopkins University, Baltimore, MD, 2University of Colorado, Aurora, CO, 3University of Cincinnati, Cincinnati, OH, 4Stanford University, Palo Alto, CA, 5University of Washington, Seattle, WA, 6Northwestern University, Chicago, IL, 7University of California San Francisco, San Francisco, CA

    *Purpose: We report the immunogenicity and safety of a third BNT162b2 vaccine in pediatric solid organ transplant recipients (pSOTRs).*Methods: Samples from pSOTRs (12-18 years) enrolled…
  • 2022 American Transplant Congress

    Bioink Based on the DECM for 3D-Bioprinting of Bionic Pancreas – First Results of Animal

    M. Klak1, K. Kosowska1, T. Bryniarski1, I. Lojszczyk1, T. Dobrzanski2, G. Tymicki1, A. Filip1, A. A. Szczepankiewicz3, R. Olkowski4, A. Kosowska4, A. Berman1, A. Kaminski4, M. Wszola1

    1Foundation of Research and Science Development, Warsaw, Poland, 2Polbionica LTD, Warsaw, Poland, 3Institute of Experimental Biology M. Nencki PAN, Warsaw, Poland, 4Medical University of Warsaw, Warsaw, Poland

    *Purpose: Tissue engineering is an interdisciplinary field involving activities based on two interrelated areas: developing new methods to repair, regenerate and replace damaged tissues and…
  • 2022 American Transplant Congress

    Bionic Pancreas – 3D Bioprinting of a Bionic Organ with a Vascular System – Results of Transplantation in Large Animals

    M. Wszola1, M. Klak2, A. Berman3, M. Kolodziejska1, T. Bryniarski1, G. Tymicki1, T. Dobrzanski1, D. Szkopek4, K. Roszkowicz-Ostrowska5, J. Wolinski5, A. Dobrzyn6, A. Kaminski7

    1Foundation of Research and Science Development, Warsaw, Poland, 2Foundation for Research and Science Development, Warsaw, Poland, 3Polbionica Ltd., Warsaw, Poland, 4Institute of Animal Physiology and Nutrition Jan Kielanowski of the Polish Academy of Sciences,, Jabłonna, Poland, 5Institute of Animal Physiology and Nutrition Jan Kielanowski of the Polish Academy of Sciences, Jablonna, Poland, 6Laboratory of Cell Signaling and Metabolic Disorders, Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw, Poland, 7Department of Transplantology and Central Tissue Bank, Medical University of Warsaw, Warsaw, Poland

    *Purpose: There is lack organs for transplantation. The transplantation of the pancreas is recommended in diabetes with complications. The combination of cell biology and 3D-bioprinting…
  • 2022 American Transplant Congress

    A Single-Center Cross-Sectional Analysis of Lipid Management in Kidney Transplant Recipients: Is It Time to Reassess KDIGO Guidelines?

    R. Saranu1, J. Pandav1, M. Balusu2, J. Azzi1, M. Y. Yeung1, M. McGrath1, E. Abdel-Basset1, S. Gabardi1, A. Chandraker1

    1Renal Division, Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA

    *Purpose: Cardiovascular disease remains the leading cause of mortality after kidney transplant, accounting for more than 30% of total deaths. Dyslipidemia is common following transplantation,…
  • 2022 American Transplant Congress

    Post-Xenotransplant Antibody Specificities Against Swine, Monkey and Human Leukocyte Antigens in Highly Sensitized Nonhuman Primate Model

    I. DeLaura, I. Anwar, M. Manook, D. Olaso, J. Yoon, R. Baldi, A. Jackson, S. Knechtle, J. Kwun

    Surgery, Duke Transplant Center, Durham, NC

    *Purpose: Xenotransplantation has been proposed as a bridge to transplant for allosensitized patients. However, the potential of xenotransplantation to broaden HLA allosensitization due to MHC…
  • 2022 American Transplant Congress

    Prevalence of Mycophenolate Mofetil (MMF) Discontinuation and Outcomes in Pediatric Kidney Transplants (PKTX): A PNRC Study

    A. Moudgil1, K. Sgambat1, E. Benoit2, A. Jain3, M. Seifert4, C. Katsoufis5, L. Harshman6, A. Mansuri7, M. Somers8

    1Nephrology, Children's National Med. Ctr., Washington, DC, 2Nephrology, Boston's Children's Hospital, Boston, MA, 3Nephrology, Wayne State University, Troy, DC, 4Nephrology, The University of Alabama, Birmingham, AL, 5Nephrology, Holtz Children's Hospital, Miami, FL, 6Nephrology, University of Iowa, Iowa City, IA, 7Nephrology, Children's Hospital of Georgia, Augusta, GA, 8Nephrology, Boston Children's Hospital, Boston, MA

    *Purpose: MMF is discontinued in PKTX for various reasons. In this Pediatric Nephrology Research Consortium (PNRC) study, we determined prevalence and reasons for MMF discontinuation…
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