2013 American Transplant Congress
Pre-Transplant HLA Immunization in Kidney Transplant Recipients Is Characterized by an Activated Peripheral B Cell Phenotype and High Serum Levels of BAFF
Purpose. Our objective was to provide the first precise study of peripheral B cell phenotype and BAFF serum level in relation with pre-transplant HLA immunization.…2013 American Transplant Congress
Re-Wiring the Molecular Circuitry of the AlloGraft To Promote Tolerance
Garvan Institute, Darlinghurst, NSW, Australia
Presentation of graft-derived antigens with correct co-stimulation drives the allo-immune response. Conversely, in the absence of these factors graft-specific tolerance may result. For DCs, the…2013 American Transplant Congress
Advagraf Immunosuppression Initiation in Kidney and Liver Transplant Recipients: 3 Month-Interim Analysis of a French Multicenter Observational Study
from the OSIRIS Study Group, France
Introduction: Once daily formulation of tacrolimus (TAC-OD) has been proven to be comparable to twice daily formulation (TAC-BID) in terms of efficacy and safety for…2013 American Transplant Congress
Anti-IL-6 Receptor (Anti-IL6R) Treatment Is Effective in Reducing Recall Antibody Responses in Sensitized HLA-A2 Skin Graft Recipients
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
Background Sensitization to HLA antigens poses significant obstacles for successful transplantation and increase risk for antibody-mediated rejection (ABMR). IL-6/IL-6R interactions are known to have a…2013 American Transplant Congress
Expedited Liver Allocation in the U.S.: A Critical Analysis
The purpose of this study is to critically analyze the distribution patterns and fate of donor livers that were allocated using an expedited placement (EP)…2013 American Transplant Congress
Foetal Outcomes for Kidney Transplant Recipients
Purpose: Kidney transplantation greatly increases the chance of pregnancy and live birth in women with end stage kidney disease of reproductive age. While maternal outcomes…2013 American Transplant Congress
ABO Antibody Removal of Plasmapheresis (PP) with Intravenous Immunoglobulin (IVIG) before ABO-Incompatible (ABOI) Kidney Transplantation
Background: ABOI kidney transplantation is an inevitable option to overcome organ shortage. Outcome of ABOI grafts improved and became equivalent to compatible grafts. There were…2013 American Transplant Congress
Alpha 1-Antitrypsin (A1AT) Prevents Pulmonary Ischemia Reperfusion Injury in Rats
Purpose: Even though lung transplantation has been the effective treatment for patients with end-stage lung diseases, pulmonary ischemia reperfusion (IR) injury continues to be the…2013 American Transplant Congress
Conversion from Calcineurin Inhibitors to Everolimus Resulted in Decrease of Serum TGF-beta and Urinary NGAL in Renal Transplant Recipients
Background and Aim: Calcineurin inhibitor (CNI) treatment has been implicated for chronic allograft dysfunction in renal transplant recipients. We aimed to investigate the effects of…2013 American Transplant Congress
Comparison of Pharmacokinetics of Once- and Twice-Daily Tacrolimus in Pediatric Kidney Transplant Recipients
Aims: Few data is available regarding the pharmacokinetic (Pk) profile of newly developed modified-release once-daily formulation of tacrolimus (MR-Tac) in children. This study investigated Pk…