ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Alloreactive Regulatory T Cells Release Distinct Subpopulations of Extracellular Vesicles Bearing Immune Regulatory Proteins and the TCR/CD3 Complex Under Antigen Specific Stimulation

    B. Schreiber, S. Tripathi, A. Sonawane, M. Blaser, S. Kuraoka, S. Singh, M. Aikawa, E. Aikawa, A. Chandraker

    Brigham and Women's Hospital, Boston, MA

    *Purpose: Extracellular vesicles (EVs) are vital mediators of intercellular communication, playing an important role in the immune synapse and the T cell response. However, regulatory…
  • 2022 American Transplant Congress

    Management of Brain-Dead Organ Donors by a Dedicated ICU Team Improves Organ Yield

    G. L. Piper1, B. E. Sullivan1, G. Boulton1, T. C. Lewis1, J. Pavone1, C. Ezzell2, D. E. Smith III3, L. Angel1, N. Moazami3, R. Montgomery1

    1NYU Langone Transplant Institute, New York, NY, 2LiveOnNY, New York, NY, 3Cardiothoracic Surgery, NYU Langone Health, New York, NY

    *Purpose: Management of brain-dead (BD) donors can be challenging in hospitals with limited ICU bed availability, lack of accessible diagnostic capabilities, and a culture that…
  • 2022 American Transplant Congress

    The Financial Burden Of Transplant – A Commercial Claims Analysis

    G. Katz-Greenberg1, O. Osazuwa-Peters1, J. Gonzalez1, S. Sanoff1, O. Oloruntoba1, N. Chan1, E. J. Gordon2, C. Scales1, A. Brookhart1, L. McElroy1

    1Duke University, Durham, NC, 2Surgery, Northwestern University Feinberg School of Medicine, OAK PARK, IL

    *Purpose: Despite access to health insurance, financial concerns are among the most prevalent patient-reported barriers to kidney and liver transplantation (KT and LT, respectively). We…
  • 2022 American Transplant Congress

    Gender Disparities in Kidney Transplantation Referral Vary by Age and Race in the Southeast US

    L. Smothers1, R. Patzer1, S. Pastan1, D. DuBay2, J. Harding1

    1Emory University, Atlanta, GA, 2Medical University of South Carolina, Charleston, SC

    *Purpose: Men (vs. women) are more likely to be waitlisted or receive a kidney transplant. Whether gender disparities exist in earlier transplant steps (i.e., referral)…
  • 2022 American Transplant Congress

    A Qualitative Comparison of Declined Hispanic and Non-Hispanic Living Liver Donor Candidates at a High-Volume Urban Transplant Center

    D. Toy1, B. Horwich1, A. Mulgaonkar1, A. Padilla2, J. L. Dodge3, N. Kaur4, H. Han3

    1Department of Medicine, University of Southern California, Los Angeles, CA, 2USC Transplant Institute, University of Southern California, Los Angeles, CA, 3Division of Gastrointestinal and Liver Diseases, University of Southern California, Los Angeles, CA, 4Department of Surgery, University of Southern California, Los Angeles, CA

    *Purpose: To compare Hispanic and non-Hispanic living liver donor candidates who were declined by a multidisciplinary selection committee at a large urban transplant center.*Methods: The…
  • 2022 American Transplant Congress

    Impact of a Transplant Pharmacy Collaborative Practice Agreement Implementation on an Institutional Medication Assistance Program Funding Utilization

    A. D. Kataria1, T. Sam1, N. Wilson1, A. Lee2, L. Cole2, D. Francis3, L. Zuniga3, B. Stein3, R. Goldstein3

    1Pharmacy, Baylor University Medical Center, Dallas, TX, 2Baylor Health Enterprise, Dallas, TX, 3Transplant, Baylor University Medical Center, Dallas, TX

    *Purpose: Post-transplant medication cost can pose a significant barrier for patient adherence and graft outcomes. Strategic selection of medication agent is often challenging and requires…
  • 2022 American Transplant Congress

    Treading the Paradigm Shift: A Single Center Comparative Study of Outcomes Between Pre-Emptive and Early Kidney Transplant with Non Pre-Emptive Kidney Transplant Recipients Innational Kidney and Transplant Institute

    E. U. Go, L. Baloloy

    Organ Transplantation and Vascular Surgery, National Kidney and Transplant Institute, Quezon City, Philippines

    *Purpose: To compare the 3-year outcome of pre-emptive and early kidney transplant recipients versus non pre-emptive recipients in our institution from January 2013 to December…
  • 2022 American Transplant Congress

    Donor-Derived Cell-Free DNA (dd-cfDNA) for Assessment of Response After Treatment of Allograft Rejection

    R. Gohh1, J. Klein2, M. Jagadeesan3, V. Rao4, M. Weir5, H. Gilligan6, G. Shekhtman7, N. Agrawal8, Y. Fu9, E. Akalin10

    1Alpert School of Medicine, Brown University, Providence, RI, 2University of Kansas Medical Center, Kansas City, KS, 3George Washington School of Medicine, Washington, DC, 4Medical University of South Carolina, Charleston, SC, 5University of Maryland, Baltimore, MD, 6Massachusetts General Hospital, Boston, MA, 7CareDx Inc., Brisbane, CA, 8CareDx Inc, Brisbane, CA, 9CareDx, Brisbane, CA, 10Montefiore Medical Center, Bronx, NY

    *Purpose: Surveillance of dd-cfDNA after therapy for rejection represents a promising strategy for monitoring post-treatment response. We assessed post-rejection kinetics of dd-cfDNA among kidney transplant…
  • 2022 American Transplant Congress

    Collaboration for Successful Transition to Adult Care in Liver Transplant: Early Outcomes of a Structured Program with Youth Engagement

    B. Kosmach-Park1, J. Kilpatrick2, A. Algeo1, K. Jones1, L. Remaley1, N. Elazzazy2, N. Jonassaint3, G. Mazariegos1

    1Transplant Surgery, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, 2Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, 3Department of Medicine and Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA

    *Purpose: To effectively transition youth to adult hepatology through a structured program and developed partnerships while promoting and maintaining optimal outcomes.*Methods: The pediatric and adult…
  • 2022 American Transplant Congress

    Use of Organ-Specific Chimeric Antigen Receptor Promotes Liver Recruitment of Regulatory T Cells

    E. Landmann1, P. Ruiz1, A. Kurt1, E. Kodela1, M. Martinez-Llordella2, A. Sanchez-Fueyo1

    1King's College London, London, United Kingdom, 2Quell Therapeutics, London, United Kingdom

    *Purpose: Owing to their potent immune-modulatory properties, regulatory T cells (Tregs) have been explored as novel cell therapy to induce allograft tolerance, with first clinical…
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