ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Outcome of Donor Derived and Community Acquired West Nile Infections in Kidney Transplant Recipients

    R. K. Thimmisetty1, G. Larrieux2, S. Wilson2, F. Barrantes1, S. Kundeling1, J. Kumar1

    1Renal Medicine Associates, Albuquerque, NM, 2Presbyterian Health Services, Albuquerque, NM

    *Purpose: Donor derived West Nile Virus(WNV) Infections can occur but rare. We are presenting four cases that were seen at our transplant center*Methods: Case 1:…
  • 2022 American Transplant Congress

    Analysis of Sars-Cov-2-Specific T-Cell Responses Using Novel Single-Cell Multiplexed Isolight in Covid-19 Convalescents

    Y. Sambandam1, J. He1, N. Vanderhyde2, L. Gallon1, J. Leventhal1, J. Mathew1

    1Northwestern University, Chicago, IL, 2IsoPlexis, Branford, CT

    *Purpose: COVID-19 has poor outcomes in transplant recipients with reduced antibody responses. However, the exact cellular immune response against SARS-CoV-2 remains largely unclear. We developed…
  • 2022 American Transplant Congress

    Is Remnant Liver Volume Ratio Less Than 30% Still Contraindication to Right Hepatectomy for Living Liver Donors?

    J. Kim, D. Choi

    Department of Surgery, Catholic University of Daegu College of Medicine, Daegu, Korea, Republic of

    *Purpose: Recently, some centers reported that extended resection with remnant/total volume ratio(RTVR) less than 30% for living donor right hepatectomy(LDRH) but there is no consensus…
  • 2022 American Transplant Congress

    A Novel Approach to Non-Invasive Multimodality Testing with Allosure and Allomap Predicts Microvascular Inflammation with High Accuracy in Kidney Transplant Recipients

    S. Parajuli, F. Aziz, N. Garg, S. E. Panzer, K. Van Hyfte, K. Degner, S. Reese, L. Ptak, N. Wilson, A. Djamali

    University of Wisconsin, Madison, WI

    *Purpose: The most prominent histologic lesion in antibody-mediated rejection (ABMR) is microvascular inflammation (MVI); however, its recognition and scoring can be challenging and poorly reproducible…
  • 2022 American Transplant Congress

    Why Females Have Weaker Tregs Than Males: Inhibitory Effects of Estrogen Receptor Signaling on Foxp3+ Treg Cell Suppressive Function

    L. M. Christensen1, T. Akimova1, G. Ge2, R. Han1, L. Wang3, C. O'Brien2, M. Levine2, W. W. Hancock3

    1Children's Hospital of Philadelphia, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3Childrens Hospital of Philadelphia, Philadelphia, PA

    *Purpose: Estrogen signaling is thought to play a role in nearly every cell type, but the biological significance of estrogen signaling via estrogen receptors in…
  • 2022 American Transplant Congress

    Triple-Knockout Pig Red Blood Cells as Potential Sources for Blood Transfusion in Alloimmunized Patients with Sickle Cell Disease

    T. Yamamoto1, M. H. Bikhet2, H. Q. Nguyen2, Y. Cui2, M. Javed2, S. S. Raza2, D. Ayares3, H. Iwase2, H. Hara2, D. K. Cooper1

    1Center for Transplantation Sciences, Massachusetts General Hospital/Harvard Medical School, Boston, MA, 2Xenotransplantation Program, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, 3Revivicor, Blacksburg, VA

    *Purpose: Blood transfusion remains important in the treatment of patients with sickle cell disease (SCD). However, alloimmunization after multiple blood transfusions is associated with patient…
  • 2022 American Transplant Congress

    Burden of Leukopenia/Neutropenia Among Adult Kidney Transplant Recipients: A Systematic Literature Review of Observational Studies

    A. Raval1, K. Kistler2, Y. Tang1, F. Vincenti3

    1Merck & Co., Inc., Kenilworth, NJ, 2Xcenda, Inc, Carrollton, TX, 3University of California, San Francisco, San Francisco, CA

    *Purpose: Leukopenia/neutropenia (L/N) may affect key treatment decisions which could result in poor clinical and economic outcomes among kidney transplant recipients (KTRs). The burden of…
  • 2022 American Transplant Congress

    Assessing the Impact of a Transplant Case Management Program on Clinical Outcomes: An Observational Cohort Study

    A. Crossman

    Healthcare Economics, Optum Health, Eden Prarie, MN

    *Purpose: Case management is commonly used by payers to attempt to improve the care their members who have complex needs such as those who undergo…
  • 2022 American Transplant Congress

    Risk for Loss of Hepatitis B Surface Antibody or Hepatitis B Reactivation in Kidney Transplant Recipients Receiving Lymphocyte Depleting Induction

    K. Paplaczyk1, C. Kane1, M. Kapugi1, K. Lang1, K. Cunningham1, C. D'Agostino1, J. Boike2

    1Pharmacy, Northwestern Memorial Hospital, Chicago, IL, 2Transplant Hepatology, Northwestern Memorial Hospital, Chicago, IL

    *Purpose: Although used in over 60% of kidney transplant recipients, the impact of lymphocyte depleting induction on hepatitis B surface antibody (HBsAb) and hepatitis B…
  • 2022 American Transplant Congress

    Vitamin D Status and Sars-cov-2 Infection in a Cohort of Renal Transplanted Patients

    A. Regalia, C. M. Alfieri, M. Campise, D. Cresseri, M. Gandolfo, P. Messa, G. Castellano

    Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico Milano, Milano, Italy

    *Purpose: Immunomodulatory and anti-inflammatory properties have been hypothesized for native vitamin D (nVD). Very little is reported about nVD and risk of Sars-CoV-2 infection (COV)…
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