2013 American Transplant Congress
Antithymocytes Globulines and Immune Senescence in Renal Transplant Patients
Background: CD4 T cell reconstitution after antithymocytes globulins (ATG) is dependent on pre-transplant thymic function and persistent ATG-induced CD4 T cell lymphopenia is associated with…2013 American Transplant Congress
Continuous Coronary Sinus Perfusion for Recovery of Hearts from Non-Heart-Beating Donors
Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, TX
Purpose: DCD donors are not usually considered for heart transplantation. Recent studies suggest that machine perfusion appears promising for improving preservation of donor hearts and…2013 American Transplant Congress
High Levels of Plasma IL-21 Together with EBV-Specific Cytotoxic T Cells (EBVTc) May Contribute Avoidance to Post-Transplant (Tx) Lymphoroliferative Disorder (PTLD) in Pediatric Kidney Tx Patients (pts) Who Had Persistent EBV Infection (PEBV)
Background: PEBV infection is associated with high risk for development of PTLD. Recent studies report a critical role for IL-21 in sustaining viral-specific Tc activity…2013 American Transplant Congress
Collapsing Glomerulopathy of the Kidney Allograft: Is It Different from Idiopathic Collapsing Glomerulopathy of Native Kidney?
Collapsing Glomerulopathy (CG) is a histological entity characterized by glomerular capillary collapse, wrinkling and retraction of the glomerular basement membrane, and glomerular epithelial cell hypertrophy…2013 American Transplant Congress
Hyperuricemia Is Associated with Both Histological Alteration in Implant Biopsy and Risk Factor of Donor’s Renal Function Decline after 1-Year in Living-Kidney Transplantation
Objective: Only living donation enables for timely kidney transplantation for patients with end stage renal disease. Donors's follow-up is often neglected, bringing up economic and…2013 American Transplant Congress
ES Cell-Derived Hematopoietic Progenitor Cells Downregulate Alloreactive T Cells Using Arginase 1
Internal Medicine, University of Iowa, Iowa City, IA; VA Medical Center, Iowa City, IA
We and others have previously reported that ES cell-derived hematopoietic progenitor cells (ESC-HPCs) induce transplantation tolerance. However the mechanisms by which this process occurs have…2013 American Transplant Congress
Systems Analysis of Innate Activation Reveals IL-1 Family Members as Key Modulators of Alloreactive T Cells Susceptibility to Regulation and Novel Targets for Therapeutic Intervention
Rational regulation of alloreactive T cells (alloT) responses is the ideal goal of tolerance promoting therapies. However, our understanding of the factors and mechanisms that…2013 American Transplant Congress
Marked Increase in Pre-Existing Morbidity among Living Kidney Donors in the United States
Cleveland Clinic, Cleveland; Beth Israel Deaconess Medical Center, Boston
IntroductionResearch suggests long-term health of living kidney donors is comparable to the general population. However, there are limited comprehensive studies of morbidity among this population…2013 American Transplant Congress
Prognostic Value of SRTR Kidney Transplant Report Cards in the United States, The
Cleveland Clinic, Cleveland; Case Western Reserve University, Cleveland
IntroductionSRTR report cards provide the basis for quality assurance of US transplant centers. There is limited data evaluating the prognostic value of report cards, informing…2013 American Transplant Congress
High BMI Is Not a Risk Factor for Mortality or Rejection Following Renal Transplantation
Obesity increases peri-operative complications in transplantation but effects on long-term kidney transplant outcomes remain controversial.We analysed U.K transplant registry data from 1st January 2004 to…
American Transplant Congress abstracts