ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Matrix Cellular Activation of Non-Phagocytic SIRP-α Stimulates NADPH-Oxidase To Promote Cell Death, Limit Blood Flow and Promote Renal Ischemia Reperfusion Injury

    N. Rogers, M. Yao, G. Csanyi, A. Rodrigues, P. Pagano, A. Thomson, J. Isenberg

    Department of Medicine, University of Pittsburgh, Pittsburgh, PA; Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA

    Ischemia reperfusion injury (IRI) remains a source of organ transplant injury and accelerant of graft rejection. Current interventions to mitigate IRI and promote tissue preservation…
  • 2013 American Transplant Congress

    Public Survey of Acceptable Financial Incentives for Living Donation: Challenging Assumptions and Reinvigorating the Debate, A

    C. Patel, M. Sohn, B. Hippen, L. Sherman, E. Gordon

    Northwestern University, Chicago; Case Western Reserve University, Cleveland; Carolinas Medical Center, Charlotte

    Background. The potential use of financial incentives to increase living kidney donation rates has generated much controversy over the potential for exploitation of and undue…
  • 2013 American Transplant Congress

    Pretransplant Donor-Specific HLA-Cw Antibodies and Risk of Antibody-Mediated Rejection

    M. Bories, O. Aubert, C. Suberbielle, A. Loupy, F. Martinez, D. Anglicheau, R. Snanoudj, M. Timsit, D. Charron, C. Legendre, R. Sberro Soussan

    Department of Kidney Transplantation, Necker Hospital, Paris, France; Department of Immunology and Histocompatibility, Saint-Louis Hospital, Paris, France; Department of Urology, Georges Pompidou European Hospital, Paris, France

    Donor-specific anti-HLA antibodies (DSA) cause acute and chronic antibody-mediated rejection (AMR) and significantly compromise allograft survival. Clinical relevance of antiHLA-Cw antibodies is still unclear with…
  • 2013 American Transplant Congress

    One Year Results of the Effects of Rituximab on Acute Humoral Rejection in Renal Transplantation: RITUX ERAH, a Multicenter Randomized Placebo Controlled Trial

    B. Sautenet, G. Blancho, M. Buchler, E. Morelon, O. Toupance, B. Barrou, D. Ducloux, B. Hurault de Ligny, B. Moulin, A. Le Gouge, Y. Lebranchu

    Nephrology, CHRU Bretonneau, Tours, France; CIC INSERM 202, CHRU Bretonneau, Tours, France; Nephrology, CHRU, Nantes, France; Nephrology, CHRU Edouard Herriot, Lyon, France; Nephrology, CHRU Maison Blanche, Reims, France; Urology, CHRU Pitie Salpetriere, Paris, France; Nephrology, CHRU Saint Jacques, Besançon, France; Nephrology, CHRU, Caen, France; Nephrology, CHRU Civil, Strasbourg, France

    Background: The treatment of acute humoral rejection (AHR) is currently based on the combination of plasmepheresis (PE), intravenous immune globulin (IVIg) and corticosteroids (CS). Patients…
  • 2013 American Transplant Congress

    Epigenetic Mechanisms Underlying Allograft Rejection: Role of the Histone Acetyltransferase, GCN-5 in T Cell Activation, Proliferation and Cytokine Production

    C. Bao, Y. Liu, L. Wang, R. Han, S. Dent, W. Hancock

    Cardiothoracic Surgery, Shanghai Jiaotong University School of Medicine, Shanghai, China; Path & Lab Med, CHOP/UPenn, Philadelphia; Carcinogenesis, MD Anderson Cancer Center, Houston

    There is currently no literature on the roles of histone acetyltransferases (HATs) in allograft biology, despite the central roles that these enzymes are thought to…
  • 2013 American Transplant Congress

    Physical Activity Level Post Kidney Transplantation: Evolution and Impact on Body Composition. Results from the CORPOS Study

    K. Moreau, A. Desseix, T. Bachelet, P. Merville, L. Couzi, C. Germain, R. Thiebaut, P. Chauveau

    Renal Transplant Unit, Pellegrin Hospital, Bordeaux, Gironde, France; Renal Transplant Unit, Pellegrin Hospital/Bordeaux II University, Bordeaux, Gironde, France; Usmr, Bordeaux II University, Bordeaux, Gironde, France; Aurad Aquitaine, Aurad Aquitaine, Gradignan, Gironde, France

    Physical activity (PA) level after kidney transplantation (KT) is little studied, although it is an important component of quality of life. Recently, it has also…
  • 2013 American Transplant Congress

    Bacteremic Sepsis in Transplantation: Can Antibiotic Duration Be Shortened by the Use of Sequential Procalcitonin and Endotoxin? A Prospective Cohort Study

    D. Florescu, T. VanSchooneveld, G. Haynatzki, L. Shafer, H. Chambers, L. Hill, A. Kalil

    University of Nebraska Medical Center, Omaha, NE

    Introduction: Solid organ transplant patients with bacteremic sepsis are usually treated with antibiotics for 10-21 days. The evidence to support this length of therapy is…
  • 2013 American Transplant Congress

    Incidence of Post Transplant BKV Infection Using Two Different Cut-Offs for BKV IgG Seropositivity

    P. Sood, D. Cronin, C. Johnson, S. Hariharan

    Medicine, University of Pittsburgh Medical Center, Pittsburgh; Surgery, Medical College of Wisconsin, Milwaukee

    Background: The study evaluated relationship of pre transplant BKV specific donor/recipient serostatus to post-transplant BKV infection, using two different cut-offs to define seropositivity.Methods: 240 adult…
  • 2013 American Transplant Congress

    Early Rehospitalization after Kidney Transplantation: Predictors and Prognosis

    M. Nair, E. Lin, A. Pai, M. Harhay, A. Huverserian, A. Mussell, A. Troxel, R. Bloom, M. Levine, P. Abt, J. Shea, P. Reese

    University of Pennsylvania, Philadelphia, PA

    Early rehospitalization occurs commonly after kidney transplantation (KT). Rehospitalization may identify patients at risk for future adverse outcomes. Methods: We performed a retrospective cohort study…
  • 2013 American Transplant Congress

    Impact of Donor HLA Mismatch Grade on Recipient HLA Locus-Specific Sensitisation in Patients Returning to the Kidney Transplant Waiting List Following a Failed Primary Kidney Allograft

    O. Gjorgjimajkoska, C. Taylor, L. Sharples, N. Chatzizacharias, S. Peacock, C. Morgan, E. Bolton, J. Bradley, V. Kosmoliaptsis

    Department of Surgery and Tissue Typing Laboratory, University of Cambridge, Cambridge, United Kingdom

    Background: The impact of Human Leukocyte Antigen (HLA) matching algorithms on kidney allocation policies in the modern era of immunosuppression is controversial. This study investigated…
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