ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Reality Capture Using Light Detection and Ranging 3D Photography of Liver Grafts for Volumetric Assessment: A Proof-of-Concept Preliminary Study

    K. E. Karakasi1, G. Katsanos2, I. Karolos3, V. Tsioukas3, G. Tsoulfas4

    1University Transplantation Surgical Clinic, Heppocrateion General Hospital, Thessaloniki, Greece, 2Transplantation, Aristitle University of Thessaloniki, Thessaloniki, Greece, 3School of Runal and Surveying Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece, 4University Transplantation Surgical Clinic, Hippocrateion’ General Hospital of Thessaloniki, Thessaloniki, Greece

    *Purpose: Reality capture uses various technical means to capture a digital 3D model representation of a subject from the real world. Whole liver graft volume…
  • 2022 American Transplant Congress

    Use of Organ-Specific Chimeric Antigen Receptor Promotes Liver Recruitment of Regulatory T Cells

    E. Landmann1, P. Ruiz1, A. Kurt1, E. Kodela1, M. Martinez-Llordella2, A. Sanchez-Fueyo1

    1King's College London, London, United Kingdom, 2Quell Therapeutics, London, United Kingdom

    *Purpose: Owing to their potent immune-modulatory properties, regulatory T cells (Tregs) have been explored as novel cell therapy to induce allograft tolerance, with first clinical…
  • 2022 American Transplant Congress

    Expanding Access to Robotic Kidney Transplantation for Candidates with High BMI. A Training Tool for Transplant Centers

    J. A. Almario Alvarez, G. Aguiluz, V. Valle, R. Bustos, S. Akshelyan, A. M. Fratti, P. D. Cocco, M. Spaggiari, I. G. Tzvetanov, E. Benedetti

    Surgery, University of Illinois at Chicago, Chicago, IL

    *Purpose: Recently published literature has demonstrated favorable outcomes for Robotic Kidney Transplant (RKT) in high BMI recipients. The University of Illinois at Chicago (UIC) has…
  • 2022 American Transplant Congress

    High TTV Load Before First Vaccine Dose is Associated with Poor Serological Response to Covid-19 Vaccination in Lung Transplant Recipients

    C. C. Van Leer Buter1, R. A. Hoek2, E. A. Verschuuren3, R. D. de Vries4, D. van Baarle1, M. van der Heiden1, H. G. Niesters1, C. GeurtsvanKessel4

    1Dept. of Medical Microbiology, University Medical Center Groningen, Groningen, Netherlands, 2Dept. of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, Netherlands, 3Dept. of Pulmonary Diseases,, University Medical Center Groningen, Groningen, Netherlands, 4Dept. of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands

    *Purpose: Torque tenovirus (TTV), a highly prevalent virus which is not known to cause pathology in humans, is currently being investigated as a marker of…
  • 2022 American Transplant Congress

    Seroprevalence of MMR and Varicella (MMRV) in Solid Organ Transplant Candidates and Seroresponse to MMRV Vaccinations

    H. Javaid1, R. Hasbun1, A. DeGolovine2, S. Jyothula3, V. Machicao4, J. Bynon5, L. Ostrosky1, M. Nigo1

    1Division of Infectious Diseases, McGovern Medical School, University of Texas Health Science Center, Houston, TX, 2Div of Renal Disease, Univ of Texas Health Science Center, Houston, TX, 3Div of Advanced Heart Failure and Transplant Cardiology, Univ of Texas Health Science Center, Houston, TX, 4Div of Transplant Hepatology, Univ of Texas Health Science Center, Houston, TX, 5Div of Immunology and Organ Transplantation, Univ of Texas Health Science Center, Houston, TX

    *Purpose: Updating live vaccines such as MMR and varicella (MMRV) is an important step in preparing patients during the pre-solid organ transplant (SOT) period. While…
  • 2022 American Transplant Congress

    The Impact of Having Potential Living Donors on Patients’ Access to Kidney Transplantation

    E. J. Gordon1, J. Lee1, R. Kang1, J. Caicedo2

    1Northwestern University Feinberg School of Medicine, Chicago, IL, 2Northwestern University, Chicago, IL

    *Purpose: Racial/ethnic disparities persist in patients’ access to living donor kidney transplantation (LDKT). Little is known about the relationship between number of potential living donors…
  • 2022 American Transplant Congress

    A Comparison of Vibration Controlled Transient Elastography, FAST, AGILE-3 and AGILE-4 Scores in Liver Transplant Recipients

    T. Arshad1, M. Tseng2, B. Anh3, T. Syed4, A. Miller5, V. Patel4, A. Asgharpour4, I. O. Michael6, S. Patel5, M. Muthiah7, M. S. Siddiqui4

    1Department of Internal Medicine, VCU, Richmond, VA, 2Internal Medicine, VCU, Richmond, VA, 3Department of Statistical Sciences & Operations Research, VCU, Richmond, VA, 4Division of Gastroenterology and Hepatology, VCU, Richmond, VA, 5VCU, Richmond, VA, 6Department of Pathology, VCU, Richmond, VA, 7National University of Singapore, Singapore, Singapore

    *Purpose: Hepatic fibrosis is a strong predictor of clinical outcomes following liver transplantation (LT), however, non-invasive fibrosis assessment remains challenging. Vibration controlled transient elastography has…
  • 2022 American Transplant Congress

    A Novel IL-2 Mutein Selectively Expands Regulatory T Cells and Prolongs Skin Graft Survival

    O. Efe1, T. J. Borges1, R. B. Gassen1, L. Morena1, A. Al Jurdi1, I. T. Lape1, G. J. Bobcock2, J. C. Madsen1, L. V. Riella1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Charlestown, MA, 2Visterra, Inc., Waltham, MA

    *Purpose: Promoting immune regulation through expansion of regulatory T cell (Treg) may allow immunosuppression minimization and improve long-term graft outcomes. Low-dose IL-2 is known to…
  • 2022 American Transplant Congress

    Triple-Knockout Pig Red Blood Cells as Potential Sources for Blood Transfusion in Alloimmunized Patients with Sickle Cell Disease

    T. Yamamoto1, M. H. Bikhet2, H. Q. Nguyen2, Y. Cui2, M. Javed2, S. S. Raza2, D. Ayares3, H. Iwase2, H. Hara2, D. K. Cooper1

    1Center for Transplantation Sciences, Massachusetts General Hospital/Harvard Medical School, Boston, MA, 2Xenotransplantation Program, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, 3Revivicor, Blacksburg, VA

    *Purpose: Blood transfusion remains important in the treatment of patients with sickle cell disease (SCD). However, alloimmunization after multiple blood transfusions is associated with patient…
  • 2022 American Transplant Congress

    Use of Dd-cfdna to Guide Tapering of Immunosuppression Therapy in Kidney Transplant Recipients

    G. Osuchukwu1, A. Trevino1, L. Beretich2, S. McCormick2, N. Kaur2, R. White2, P. Gauthier2

    1Victoria Kidney and Dialysis Associates, Victoria, TX, 2Natera, Inc., Austin, TX

    *Purpose: Continuous administration of immunosuppressive therapy (IST) is required to avoid allograft rejection in transplant recipients. However, these therapeutic interventions can lead to significant side…
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