2013 American Transplant Congress
IL-2 Antagonist Induction Therapy Preserves Renal Function in Liver Transplant Recipients
Pharmacy, MUSC, Charleston, SC; Transplant, MUSC, Charleston, SC
Background: Studies have produced varying results regarding whether IL-2 antagonist induction improves outcomes, including renal function and patient and graft survival in liver transplantation. This…2013 American Transplant Congress
Metabolomic Distinctions between Renal Allograft Recipients on Monotherapy Sirolimus or Tacrolimus Maintenance Therapy
Background. Sirolimus and Tacrolimus have distinct mechanisms of action with distinct side effect profiles. In order to gain mechanistic insights into the differing effects of…2013 American Transplant Congress
Delayed Kidney Graft Function in SPK Recipients Is Associated with Poor Long-Term Outcomes
The association of delayed kidney graft function (DGF) with long-term clinical outcomes in simultaneous pancreas kidney (SPK) transplant recipients is largely unknown. To address this…2013 American Transplant Congress
Disease Severity Index Based on Dual Cholate Clearances and Shunt Identifies Primary Sclerosing Cholangitis Waiting List Patients at Risk for Clinical Complications, A
Gastroenterology and Hepatology, University of Colorado, Aurora, CO
A. Purpose: MELD may not adequately assess the risks for clinical complications in listed Primary Sclerosing Cholangitis (PSC) patients compared to a disease severity index…2013 American Transplant Congress
Prolonged Cold Ischemia Increases the Early Infiltration and Effector Functions of Memory CD8 T Lymphocytes in Cardiac Allografts
Immunology, Cleveland Clinic, Cleveland, OH
Introduction: During organ transplantation, ischemia-reperfusion injury (IRI) is an inescapable challenge that detrimentally impacts graft outcome. While I/R induced molecular mechanisms mediating injury of ischemic…2013 American Transplant Congress
Early Steroid Avoidance Reduces the Chance for a Subsequent Transplant in Renal Transplant Recipients with Graft Failure
Early steroid avoidance (SA) in renal transplantation has been associated with more acute rejections compared to steroid continuation (SC) protocols. After graft failure, the long…2013 American Transplant Congress
Novel Population of Bone Marrow-Derived Granulocytes Express FasL and Perforin and Mediate Early Ischemic Injury, A
Immunology, Cleveland Clinic, Cleveland, OH
Introduction: Recent studies from our laboratory have documented a novel population of bone marrow derived granulocytes which are induced upon skin inflammation and are required…2013 American Transplant Congress
Requirement for T Cell Intrinsic MyD88 for Treg Homeostasis in Transplantation
The TLR-MyD88 signaling pathway enables the innate immune system to sense inflammation and promote adaptive immune responses. TLRs are expressed on T cells as well,…2013 American Transplant Congress
Deceased Kidney Donor Acute Tubular Necrosis and the Development of Delayed Graft Function
Background: Acute kidney injury (AKI) in the donor kidney may contribute to delayed graft function (DGF), heightened immunologic risk, and progressive graft fibrosis, thereby affecting…2013 American Transplant Congress
Diabetes Significantly Impacts Quality of Life Following Kidney Transplant
Dept of Pharmacy Services, MUSC, Charleston, SC; Dept of Transplant Surgery, MUSC, Charleston, SC
Purpose: Kidney transplant (KTx) has the potential to substantially improve quality of life (QOL) through improvements in performance status and life expectancy. Few studies have…
American Transplant Congress abstracts