2022 American Transplant Congress
Strada Deficiency Results in Inhibition of Tumor Suppressor Gene Liver Kinase B1 Resulting in Epithelial Mesenchymal Transition Leading to Chronic Murine Lung Allograft Rejection
St. Joseph’s Hospital and Medical Center, Phoenix, AZ
*Purpose: Recently we demonstrated that tumor suppressor gene Liver Kinase B1 (LKB1) is down regulated in lung biopsies and in the circulating exosomes of lung…2022 American Transplant Congress
Contacts Between Organ Donor Families and Their Recipients is Therapeutic for Both Sides in Most Cases
Nicholas Green Foundation, La Canada Flintridge, CA
*Purpose: The study's purpose is to discover if making it possible for organ donor families to contact their recipients -- when both sides express the…2022 American Transplant Congress
Pre-Transplant Desensitization Utilizing Intravenous Immune-Globulin and Tocilizumab: A Single Center Experience
Virginia Commonwealth University Health System, Richmond, VA
*Purpose: Highly sensitized end stage kidney disease patients face a huge barrier to transplant due to lack of effective pre-transplant desensitization therapies. Various strategies have…2022 American Transplant Congress
Use of Three-Dimensional Volumetric Analysis to Monitor Acute Rejection in a Face Transplant Recipient
*Purpose: The purpose of this study is to determine the feasibility of using 3D facial stereography to monitor volume changes in a facial allograft, and…2022 American Transplant Congress
Hypothermic Pulsatile Flush of Hepatitis C Virus (HCV) RNA Positive Kidney Reduces Viral Load
*Purpose: Does Hypothermic pulsatile flush of hepatitis C virus (HCV) RNA positive kidney reduce the viral load?*Methods: Unutilized, HCV RNA-positive deceased donor kidneys were obtained…2022 American Transplant Congress
Sirolimus Use Is Associated With An Improved Immune Response To Covid-19 Vaccination In Kidney Transplant Recipients
*Purpose: Kidney transplant recipients (KTRs) are highly vulnerable to severe COVID-19, however are poorly protected by vaccination. Additional vaccine doses have achieved limited improvements in…2022 American Transplant Congress
Pretransplant Recipient TNFR2+T Regulatory Cell Frequency Predicts Long-Term Outcomes After Kidney Transplantation
McGill University Health Centre, Montreal, QC, Canada
*Purpose: Pre-transplant indices capable of predicting long-term renal allograft function could improve graft allocation strategies. We previously associated pretransplant frequency of Tumor Necrosis Factor Receptor…2022 American Transplant Congress
Exosomal TGFbeta:LAP as Immunosuppressive Mediator of Allo-Tolerance
*Purpose: TGFβ has long been known as a key component in tolerance mediated by Treg cells. Here we show that, unlike IL10, but like CD39/CD73,…2022 American Transplant Congress
The Low Estimated Glomerular Filtration Rates at 6 and 12 Months After Living Kidney Transplantation Are Independent Risk for Graft Failure
*Purpose: The low estimated glomerular filtration rate (eGFR) at 1 year after kidney transplantation was demonstrated to be the risk for graft failure in the…2022 American Transplant Congress
Conversion of Tacrolimus Immediate Release to LCP Tacrolimus in Obese Kidney Transplant Recipients
*Purpose: Data describing the safety, efficacy and conversion ratio of tacrolimus immediate release (IR) to LCP-tacrolimus (LCP) in obese patients (BMI > 30) is lacking.…
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