ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Role of Foxp3 for Augmented Homeostatic Proliferation of Treg, The

    Y. Lin, D. Rothstein

    Thomas E. Starzl Transplantation Institute, Pittsburgh, PA

    CD4+Foxp3+ Tregs play a critical role in transplant tolerance. Foxp3 does not initiate thymic differentiation of natural Treg (nTreg), but is essential for later differentiation…
  • 2013 American Transplant Congress

    Racial Differences and Income Disparities Are Associated with Worse Allograft and Death Outcomes in Kidney Transplant Recipients with Lupus Nephritis

    R. Nee, K. Abbott, D. Little, R. Ramsey-Goldman, L. Agodoa, F. Hurst, R. Jindal

    Nephrology, Walter Reed National Military Medical Center, Bethesda, MD; Surgery, Walter Reed National Military Medical Center, Bethesda, MD; Rheumatology, Northwestern University, Chicago, IL; NIDDK, NIH, Bethesda, MD; FDA, Silver Spring, MD

    Background: An analysis of income disparities and racial differences on renal transplant outcomes in recipients with lupus nephritis (LN) has not been reported.Methods: We identified…
  • 2013 American Transplant Congress

    Superior Renal Function in an Everolimus-Based Calcineurin Inhibitor Free Regimen Compared to Standard Cyclosporine/Mycophenolate and Low Cyclosporine/Everolimus: Follow-Up of the HERAKLES Study at Month 24

    K. Budde, W. Arns, C. Sommerer, F. Lehner, M. Zeier, H. Neumayer, M. Guba, J. Jacobi, P. Weithofer, C. May, D. Baeumer, E. Paulus, O. Witzke

    HERAKLES Study Group, Germany; Novartis Pharma, Nuremberg, Germany

    Aim: To follow up (FU) on the evolution of renal function (RF) of immunosuppressive regimens with different calcineurin inhibitor (CNI) exposure at month (Mo)24 post…
  • 2013 American Transplant Congress

    Pre-Transplant Immunologic Risk Assessment and Immune Monitoring of Kidney Transplant Recipients with Pre-Transplant Donor-Specific Anti-HLA Antibodies

    K. Marfo, M. Ajaimy, M. Lubetzky, A. Colovai, P. Masiakos, G. de Boccardo, E. Akalin

    Montefiore-Einstein Center for Transplantation, Bronx, NY

    Background: We aimed to investigate the importance of pre-transplant immunologic risk assessment of kidney transplant recipients with donor-specific anti-HLA antibodies (DSA) and immune monitoring of…
  • 2013 American Transplant Congress

    Characterization of Human CD8+/TCR-/CD56dim/- Facilitating Cells In Vivo and In Vitro

    Y. Huang, M. Elliott, T. Miller, L. Bozulic, D. Corbin, Y. Wen, H. Xu, S. Ildstad

    Institute for Celllular Therapeutics, University of Louisville, Louisville, KY; Regenerex, LLC, , Louisville, KY

    We previously reported that bone marrow-derived CD8+/TCR- graft facilitating cells (FC) significantly enhance engraftment of HSC and prevent GVHD in mouse recipients. We have presently…
  • 2013 American Transplant Congress

    Choice of Induction Therapy in Kidney Transplant: It’s Race Not PRA

    N. Pilch, D. Taber, B. Thomas, S. Denmark, A. Lin, J. McGillicuddy, C. Bratton, P. Baliga, K. Chavin

    MUSC

    Background: rATG and IL-2RA are the most common induction agents used for KTX. There is no consensus on choice of induction. The aim of this…
  • 2013 American Transplant Congress

    Improved Renal Function of an Everolimus/Enteric-Coated Mycophenolate Sodium Regimen after Calcineurin Inhibitor Withdrawal in De Novo Renal Transplant Patients: 5 Years Follow-Up of the ZEUS Trial

    K. Budde, O. Witzke, C. Sommerer, P. Reinke, U. Eisenberger, E. Paulus, M. Porstner, C. May, W. Arns, F. Lehner

    ZEUS Study Group, Germany; Novartis Pharma, Nuremberg, Germany

    Aim: To follow-up (FU) on renal function (RF), efficacy and safety after conversion to an Everolimus (EVE)/Enteric-Coated Mycophenolate Sodium (EC-MPS) regimen after cyclosporine A (CsA)…
  • 2013 American Transplant Congress

    Outcome on Renal Function of an Everolimus Based Therapy after Calcineurin Inhibitor Withdrawal in Maintenance Renal Transplant Recipients: 4 Year Data of the APOLLO Trial

    K. Budde, C. Sommerer, P. Reinke, H. Haller, W. Arns, O. Witzke, B. Suwelack, C. May, D. Baeumer, E. Paulus, T. Rath

    APOLLO Study Group, Germany; Novartis Pharma, Nuremberg, Germany

    Objective: Assessment of renal function, safety and efficacy of an Everolimus (EVE) regimen after Calcineurin-Inhibitor (CNI) withdrawal in maintenance kidney allograft recipients.Methods: In an open-label,…
  • 2013 American Transplant Congress

    Five-Year Outcomes by Donor Type from the Long-Term Extension of the Belatacept BENEFIT-EXT Study

    A. Durrbach, S. Florman, R. Zhang, P. Lang, F. Lehner, P. Massari, V. Garcia, L. Pupim, F. Muehlbacher

    Bicêtre Hosp, France; Mt Sinai Med Cntr, NY; Tulane Univ, LA; Hôpital Henri Mondor, France; Med Hochschule Hannover, Germany; Univ Catolica de Cordoba, Argentina; Hosp Dom Vicente Scherer, Brazil; BMS, NJ; Medical Univ of Vienna, Austria

    Introduction: Long-term extension (LTE) results of BENEFIT-EXT demonstrated a consistent safety profile and sustained renal function improvement with belatacept vs CsA over time. Here we…
  • 2013 American Transplant Congress

    Excellent Outcome Following Transplant Using Kidneys from Deceased Donors with Severe Acute Kidney Injury

    R. Heilman, H. Khamash, J. Huskey, M. Smith, N. Katariya, A. Moss, D. Mulligan, K. Reddy

    Mayo Clinic, Phoenix, AZ

    Background: Our aim was to determine the outcome of transplanting kidneys from selected donors with severe AKI.Methods: We selected all patients receiving single organ deceased…
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