2013 American Transplant Congress
Efficacy and Safety of Single Fixed-Dose Rituximab for Recurrent Glomerulonephritis Post-Transplantation
Barnes-Jewish Hospital, St. Louis, MO; Washington University School of Medicine, St. Louis, MO
Purpose: Rituximab, using a multi-dose regimen based on body surface area, has been used for recurrent glomerulonephritis (GN) post-renal transplant with variable success. We examined…2013 American Transplant Congress
LCP-Tacro Improves TAC-Induced Tremors: Preliminary Analysis of Switching STudy of Kidney TRansplant PAtients with Tremor to LCP-TacrO (STRATO): An Exploratory Study
Neurotoxicity occurs in up to 50% of kidney transplant recipients (KTR). Tremor is the most common manifestation of neurotoxicity. It is believed that Tacrolimus (TAC)…2013 American Transplant Congress
Pediatric Kidneys Can Be Used To Expand the Donor Pool: An Analysis of Scientific Registry of Transplant Recipients Data
Internal Medicine, UIHC, Iowa City, IA; Surgery, UIHC, Iowa City, IA
Introduction: One of the strategies promoted to increase the donor pool, is to use kidneys from pediatric deceased donors, but criteria to use them en…2013 American Transplant Congress
Allocating Deceased Donor Kidneys to High PRA Patients: A Simulation
Degree of sensitization in kidney transplant candidates ranges from calculated PRA (CPRA) 0%-100%, depending on the proportion of the donor pool against whom the candidate…2013 American Transplant Congress
Outcomes at Five Years in Black/African-American Kidney Transplant Recipients from the Long-Term Extension of the Belatacept BENEFIT and BENEFIT-EXT Studies
Introduction: Previously reported long-term results of BENEFIT & BENEFIT-EXT demonstrated a consistent safety profile & sustained improvement in renal function vs CsA over time. Here…2013 American Transplant Congress
Pancreas Transplant Outcomes May Be Dependent on Center Experience
Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis
Introduction: The number of pancreas transplants (PTx) nationwide is declining, raising concern that some centers may experience low transplant volume; low volume has been associated…2013 American Transplant Congress
Phase 3, Double-Blind, Multi-Center, Non-Inferiority, Randomized Study To Examine the Efficacy and Safety of LCP-Tacro™ Tablets, Once Daily, Compared to Prograf® Capsules, Twice Daily, in Combination with Mycophenolate Mofetil in De Novo Adult Kidney Transplantation: Baseline Characteristics, A
This large, multi-continent, Phase 3, double-blind, randomized, active comparator non-inferiority trial will compare efficacy and safety of a once-daily controlled agglomeration formulation of tacrolimus with…2013 American Transplant Congress
Urinary Metabolomic Pattern Varies over Time and May Be Different in Patients Receiving Cyclosporine or Tacrolimus
EA4245, Université François Rabelais, Tours, France
The tools currently available for clinical monitoring of kidney graft dysfunction are not optimal. Metabolomics is a post-genomic application for analysis of low-molecular weight compounds,…2013 American Transplant Congress
Improved Bioavailability of MELTDOSE Once-Daily Formulation of Tacrolimus (LCP-Tacro) with Controlled Agglomeration Allows for Consistent Absorption over 24 Hrs: A Scintigraphic and Pharmacokinetic Evaluation
Veloxis Pharmaceuticals, Edison, NJ
MeltDose® is a process technology intended to enhance oral bioavailability of poorly water soluble compounds. We evaluated the transit time, pharmacokinetic (PK) profile and site…2013 American Transplant Congress
Delayed HCC MELD Exception Score Improves Disparity in Access to Liver Transplant
Background: In the US, wait-list dropout is lower and the transplant rate higher for candidates with standard MELD exception for hepatocellular carcinoma (HCC) than for…
American Transplant Congress abstracts