2013 American Transplant Congress
Immune Suppressant Effect of Erythropoietin Alpha on Human Allo-Reactive T Cell Responses
Renal Division, Department of Medicine, Mount Sinai, New York
Recent clinical studies showed that complete correction of anemia with erythropoietin (EPO) therapy improves human kidney transplant outcomes, but mechanisms underlying this protective effect are…2013 American Transplant Congress
2B4 Induced by Selective CD28 Blockade Functionally Regulates Alloreactive Memory CD8+ T Cell Responses
Emory Transplant Center, Emory University, Atlanta, GA; Bristol-Myers Squibb, Princeton, NJ
Studies in both murine and NHP models have shown that CTLA-4Ig-resistant rejection is mediated by CD8+ T cells, particularly memory CD8+ T cells. Because CTLA-4…2013 American Transplant Congress
Tuberculosis in Kidney Transplant – 10 Years Experience
Nephrology Division, Hospital do Rim e Hipertensão, Sao Paulo, Brazil
Introduction: Tuberculosis infection (TB) increases morbidity and mortality after kidney transplantation (TX) and poses diagnostic and therapeutic challenges. The incidence of TB among solid organ…2013 American Transplant Congress
HLA Antibody Increase Associated with Cardiac Surgery
Increases in titer or de novo production of HLA antibody are potential sequelae of pregnancy, transfusion, or transplantation. It has also been reported that pro-inflammatory…2013 American Transplant Congress
Using Non-Invasive, Real-Time Imaging Technology To Assess the Status of Donor Kidneys
Purpose. The extent of acute tubular necrosis (ATN) in renal tubules may provide valuable prognostic data regarding post-transplant renal function of donor kidneys. We used…2013 American Transplant Congress
Nutraceuticals Extenuate Kidney Ischemia/Reperfusion Injury in Rats Via HO-1 Induction
Background: The induceable Hemeoxygenase-1 (HO-1) is the rate limiting step in the conversion of heme into biliverdin, carbon monoxide (CO) and free iron (Fe2+). Up-regulation…2013 American Transplant Congress
Proteinkinase C Alpha Contributes to Impairment of Renal Blood Flow and Inflammation in Hypoxia Induced Renal Ischemia Reperfusion Injury (IRI)
Background Renal ischemia reperfusion injury (IRI) leads to delayed graft function (DGF) after kidney transplantion and contributes to acute transplant rejection as well as…2013 American Transplant Congress
Association between Early Progression in Chronic Kidney Disease Stage Following Liver Transplantation and Graft Survival
Introduction: Renal dysfunction before and after liver transplantation is a significant predictor of graft survival (GS). This study aims to characterize the relationship between early…2013 American Transplant Congress
Prolonged Delayed Graft Function Is Associated with Inferior Patient and Kidney Allograft Survivals
Nephrology Division, Hospital do Rim e Hipertensão, São Paulo, Brazil
Introduction: The incidence of delayed graft function (DGF) is variable according to donor/recipients demographics. It is still unclear the influence of DGF on clinical outcomes…2013 American Transplant Congress
Chimeric Antibody Against LFA-1 Does Not Synergize with Belatacept in Primate Renal Transplantation, A
Background: Clinical studies with belatacept have shown improved graft function at the cost of increased rates of and more severe early rejection. Blockade of LFA-1…