2013 American Transplant Congress
Everolimus-Facilitated Reduction of Tacrolimus in De Novo Liver Transplant Recipients Achieves Comparable Overall Efficacy with Fewer Biopsy-Proven Acute Rejections Versus Standard Tacrolimus: 24-Month Results of a Randomized Trial
Purpose: The H2304 (NCT00622869) study compared the efficacy and safety of concentration-controlled everolimus (EVR) to eliminate or to reduce tacrolimus (TAC) vs standard TAC (TAC-C)…2013 American Transplant Congress
Lack of Clinical Factors Increasing Quantitative Interstitial Fibrosis after Renal Transplantation under a Lower Target Trough Strategy of Tacrolimus
INTRODUCTION AND OBJECTIVES: Chronic allograft injury is a multi-factorial process based on immunologic and non-immunologic factors. Patients with the CYP3A5*3/*3 genotype (non-expressers) require a lower…2013 American Transplant Congress
Prospective and Randomized Trial Comparing Tacrolimus Versus Sirolimus after Simultaneous Pancreas-Kidney Transplantation
Institut de Transplantation-Urologie-Néphrologie, Nantes University Hospital, Nantes, France
Introduction. Minimizing or sparing potentially nephrotoxic and diabetogenic immunosuppressants could represent an advantage following simultaneous pancreas-kidney transplantation (SPK-Tx).Purpose. We report here the actual one-year result…2013 American Transplant Congress
Variability of IMPDH-Activity in Long-Term MPA Mediated Immunosuppression
Purpose of this study was to examine wether the long term exposure for mycophenolate mofetil (MMF) or enteric coated form (EC-MPS) is leading to an…2013 American Transplant Congress
Suppression of Acute Rejection by Administration of Prostaglandin E2 Receptor Subtype 4 (EP4) Agonist in a Rat Heterotopic Small Bowel Transplantation Model
Background: Prostaglandin E2 (PGE2)PGE2 receptor subtype 4 (EP4) signaling is known to modulate the inflammation process. Several studies have demonstrated the potential utility of EP4-selective…2013 American Transplant Congress
Kidney Injury Molecule-1 and Osteopontin: New Markers for Prediction of Early Kidney Transplant Rejection
Background. Kidney injury molecule-1 (KIM-1) and osteopontin (OPN) play important roles in immune regulation. We hypothesized that serum KIM-1 and OPN might serve as biomarkers…2013 American Transplant Congress
Health-Related Quality of Life and Adherence to Medication in Kidney Transplantation: A Longitudinal Analysis
AimTo analyse the influence of dialysis type on adherence to immunosupressive medications (IS) and HRQoL before and after KT.Material and Methods. Between years 2004-2008 156…2013 American Transplant Congress
Impact of Vitamin D, Bisphosphonate, and Combination Therapy on Bone Mineral Density in Kidney Transplant Patients
Background: Osteoporosis can develop and become aggravated in a large number of kidney transplant patients; however, the best preventive options for post-transplant osteoporosis remain controversial.Methods:…2013 American Transplant Congress
Utility of Serial Allograft Biopsies (AGBx) during Delayed Graft Function (DGF) in Renal Transplantation, The
Renal Transplant Center, Henry Ford Hospital, Detroit, MI
Background: DGF complicates approximately 30% of deceased donor (DD) kidney transplants and rarely also occurs following live donor (LD) kidney transplants (KTX). KTX in DGF…2013 American Transplant Congress
Change of Single-Kidney Glomerular Filtration Rate in Kidney Donors after Kidney Donation, The
Background: It is well known that remaining nephrons after loss of renal tissue showed compensatory hyperfiltration in chronic kidney disease. But in healthy populations without…