2013 American Transplant Congress
Anti-CD20 Antibody Therapy for Antibody-Mediated Rejection of Renal Allografts in a Mouse Model
Immunology, Cleveland Clinic, Cleveland, OH; Osaka University, Suita, Japan
INTRODUCTION: We have reported murine recipients lacking the chemokine receptor CCR5 reject renal allografts with marked C4d deposition in peritubular capillaries and high serum donor-reactive…2013 American Transplant Congress
Impact of Donor Kidney Disease on Outcomes Following Deceased Donor Kidney Transplantation
Background: Increasing numbers of Donation after Circulatory Death (DCD) kidneys are retrieved from Expanded Criteria (EC) donors, but uncertainties persist regarding how best to assess…2013 American Transplant Congress
Incidence and Risk Factors for Leukopenia in Kidney Transplant Recipients Receiving Valganciclovir for Cytomegalovirus Prophylaxis
Multi-Organ Transplant Program, Toronto General Hospital, University of Toronto, Toronto, ON, Canada
Background: Cytomegalovirus (CMV) is a major cause of morbidity and mortality after kidney transplantation. Valganciclovir is primarily used for CMV prophylaxis but is known to…2013 American Transplant Congress
Identification of Urinary Biomarkers during Antibody-Mediated Rejection in a Murine Kidney Transplant Model
Immunology, Cleveland Clinic, Cleveland, OH; Osaka University, Suita, Japan
INTRODUCTION: Diagnosing antibody-mediated rejection (AMR) can be difficult without an invasive graft biopsy. A specific, non-invasive biomarker to monitor immunological graft status would facilitate diagnosis…2013 American Transplant Congress
Donation after Cardiac Death and Higher Donor Risk Index Are Associated with End-Stage Renal Disease after Liver Transplant
Background: The limited organ supply has led to greater use of liver allografts with higher donor risk indices (DRI) and/or donated after cardiac death (DCD).…2013 American Transplant Congress
Outcome of Hepatitis B and C Virus Associated Hepatocellular Carcinoma Occurring after Renal Transplantation
Background: Chronic hepatitis B (HBV) and C (HCV) virus infections are causes of morbidity and mortality in kidney transplant recipients (KTR). Immunosuppressive agents enhance HBV…2013 American Transplant Congress
Role of Graft-Derived MCP1 in Antibody-Mediated Rejection of Cardiac Allografts
INTRODUCTION: Macrophages are components of the innate immune response and quickly infiltrate tissues during inflammation. Their role in antibody-mediated rejection (AMR) remains unclear. We have…2013 American Transplant Congress
Specific Lymphocyte Trafficking Via High Endothelial Venules Is Required for Tolerance
University of Maryland, Baltimore
Background: CD40-CD40L costimulatory blockade plus donor-specific splenocyte transfusion (DST) induces tolerance concurrent with regulatory T cell (Treg) induction in the lymph node (LN). Treg are…2013 American Transplant Congress
Donation after Circulatory-Death in the UK
Background: The number of deceased donors in the UK has increased from 809 in 2007-8 to 1088 in 2011-2. This increase can be ascribed, predominantly,…2013 American Transplant Congress
Influence of Donor’s and Recipent’s CMV Serostatus on the Allograft Survival and CD8 Cell Compartment Evolution in Kidney Transplant Recipient: A Monocentric Cohort Study
Background : Despite the large body of literature, no clear causal relationship between chronic CMV infection of kidney transplants and long-term graft dysfunction has yet…
American Transplant Congress abstracts