2013 American Transplant Congress
N-Acetylcystein and High Dose Atorvastatin To Reduce Oxidative Stress in a Ischemia/Reperfusion Model in Kidney Rat
Ischemia/reperfusion injury (I/R) is characterized by an increase in reactive oxygen species production, pro-inflammatory cytokine release and activation of endothelial cells leading to cell damage…2013 American Transplant Congress
Survival Advantage from Listing for Elderly Patients Awaiting Kidney Transplant
Cambridge University, Cambridge, United Kingdom
Introduction Elderly patients (age over 65) now represent the largest population starting renal replacement therapy. However their access to, and benefit from, transplantation remains unclear.…2013 American Transplant Congress
Opposing Roles of TIM-4 on Dendritic Cells vs Macrophages in Transplant Rejection
Transplantation Research Center, Brigham&Women's Hospital, Boston, MA
T cell immunoglobulin and mucin domain (TIM)-4, expressed on dendritic cells and macrophages, functions both as a costimulatory molecule and a phosphatidylserine receptor, mediating phagocytosis…2013 American Transplant Congress
IGL-1 Solution Prevents Proteolysis during Cold Steatotic Liver Graft Preservation
Antecedents: Liver transplantation remains the sole therapy for a certain number of liver diseases at end stage. Liver proteolysis that occurs during cold storage influences…2013 American Transplant Congress
CD4+ but Not CD8+ Memory T Cells Escape Granzyme B Mediated Regulation by DN-Treg
Memory T cell (Tm) homeostasis is poorly understood and is a critical challenge to controlling transplant rejection. At present there are no effective clinical strategies…2013 American Transplant Congress
Impact of Donor and Recipient Pretransplant EBV Antibody Status on PTLD Incidence in Adult Kidney Transplant Recipients
Surgery and Lab Medicine and Pathology, U Mn, Mpls, MN
We studied the impact of pretransplant (pretx) EBV antibody (ab) status on the incidence of PTLD in adult primary kidney tx recipients. Between 1/2002 and…2013 American Transplant Congress
Efficacy and Safety of Influenza Vaccination during the First Six Months Post-Transplantation
Our goal was to study the efficacy and safety of influenza vaccination during the first six months post-transplantation.A prospective cohort study of consecutive cases of…2013 American Transplant Congress
Central Role of Mitochondrial Energy Metabolism in Foxp3+ Treg Cell Function and Allograft Survival
Increasing Foxp3+ regulatory T-cell (Treg) numbers and/or their function are innovative approaches to immunosuppression post-transplantation. T-effector (TE) and Treg cells have differing metabolic needs, but…2013 American Transplant Congress
Noncompliance as a Major Cause of Late Graft Failure in Kidney Transplantation
While many clinical reports exclude mention of patient noncompliance, our experience includes those who often stop and then restart or even completely stop taking their…2013 American Transplant Congress
Gender Disparities in Renal Replacement Therapy in Pediatric End Stage Renal Disease
Among adults with End Stage Renal Disease (ESRD), there is evidence that females are less likely to receive renal transplant compared to males and blacks…
American Transplant Congress abstracts