ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Late after Lung Transplantation Many Patients Have Donor-Specific HLA Antibodies (DSA) and High DSA Levels Appear To Be Associated with Poor Outcomes

    L. Baxter-Lowe, J. Singer, S. Hays, J. Kukreja, J. Golden, L. Leard

    UCSF, San Francisco

    The presence of DSA after lung transplantation has been associated with adverse outcomes, but the utility of long-term routine screening remains controversial. For lung recipients…
  • 2013 American Transplant Congress

    Liver Transplant Outcomes for Primary Sclerosing Cholangitis: Role of Ethnicity and IBD

    N. Kemmer, G. Neff, E. Cece, E. Parkinson, A. Alsina

    Division of Liver Transplantation, Tampa General Medical Group, Tampa, FL

    Liver Transplantation (LT) provides excellent long-term outcomes for recipients with primary sclerosing cholangitis (PSC). Though the association between inflammatory bowel disease (IBD) and PSC is…
  • 2013 American Transplant Congress

    Angiopoietin2: A Prognostic Marker in Kidney Transplantation

    W. Westendorp, L. Koudstaal, J. Damman, J. Burgerhof, M. Seelen, H. van Goor, R. Ploeg, H. Leuvenink

    Surgery, University Medical Center Groningen, Groningen, Netherlands; Pathology, University Medical Center Groningen, Groningen, Netherlands; Epidemiology, University Medical Center Groningen, Groningen, Netherlands; Nephrology, University Medical Center Groningen, Groningen, Netherlands; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom

    Organs derived from deceased brain dead (DBD) donors show worse organ function and more acute rejection episodes than organs derived from living donors. Human studies…
  • 2013 American Transplant Congress

    Role of Immunosuppression on Hyperuricemia and Proteinuria Affecting Graft Survival, The

    U. Cakir, I. Berber, E. Gurluler, N. Gures, A. Alim, A. Gurkan

    Transplant Center, Acibadem University, Istanbul, Turkey

    The negative impact of serum uric acid (UA) on the function of transplanted kidneys is still being investigated. We aimed to evaluate the predictive value…
  • 2013 American Transplant Congress

    Outcome of Kidney Transplants (KT) in U.S. Adult HUS Patients: A Ten Year Database Analysis

    A. Santos, C. Faldu, X. Wen, M. Casey, C. Bucci, R. Aiyer, I. Zendejas, S. Rehman

    Univ of Florida, Gainesville, FL; Private Practice, W Melbourne, FL

    Purpose. Large population studies on the outcome of HUS KT recipients (HUS-KTR) are limited. We aimed to determine their patient and graft outcomes compared with…
  • 2013 American Transplant Congress

    Introducing a Reliable Hindlimb Transplantation Model in the Mouse Utilizing Innovative Supermicrosurgical Techniques for Vascular Anastomosis

    J. Grahammer, Q. Mao, S. Schneeberger, R. Sucher, W. Lee, G. Brandacher

    Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; Visceral-, Transplant and Thoracic Surgery, Innsbruck Medical University, Innsbruck, Tirol, Austria; Surgery, Nanjing University School of Medicine, Nanjing, Jiangsu, China

    Investigating the fundamental mechanisms of transplant immunology relies on reproducible animal models. The orthotopic hindlimb model we propose here using a refined technique for vascular…
  • 2013 American Transplant Congress

    Hepatitis C Virus Infection Promotes Development of Fibrosis through Modulation of miR200c Regulates Growth Factor Signaling through FAP-1

    S. Ramachandran, H. Basha, J. Crippin, W. Chapman, T. Mohanakumar

    Surgery, Medicine, Pathology & Immunology, Washington University School of Medicine, St. Louis, MO

    Background: Hepatitis C virus (HCV) induced liver disease is the leading indication for liver transplantation (LTx). Reinfection of HCV is a universal phenomenon, and accelerated…
  • 2013 American Transplant Congress

    Abrogation of Chronic Rejection Involves Down Regulation of mTOR/Rac1 Pathway

    M. Kloc, N. Tejpal, J. You, J. Sidhu, M. Ganachari, L. Zhang, R. Ghobrial

    Surgery, The Methidst Hospital and The Methodist Hospital Research Institute, Houston, TX

    Background: Chronic rejection is the major obstacle to long-term survival of organ allografts. We study the cellular and molecular pathways involved in the inhibition of…
  • 2013 American Transplant Congress

    Effect of Proteasom Inhibition with Bortezomib Associated with Steroids on the Decrease of HLA Antibodies before Transplantation

    O. Aubert, C. Suberbielle, R. Gauthe, E. Nnang, H. Francois, A. Durrbach

    Nephrology Department, IFRNT, Bicetre Hospital, Le Kremlin Bicetre, France; U1014, INSERM, Villejuif, France; Histocompatibility Lab, APHP, Paris, France; Rouen Hospital, Rouen, France

    IntroductionCurrently, all proposed treatments for desensitivation are often ineffective or transient (plasmapheresis, intravenous immunoglobulin or rituximab) to control the production of antiHLA antibodies by B…
  • 2013 American Transplant Congress

    Early Experience with 3-Month Ciprofloxacin Prophylaxis for BK Infection in Renal Transplantation

    S. Patel, R. Knight, L. Moore, A. Lehnert, A. Agbetoba, J. DeVos, A. Gaber

    The Methodist Hospital, Houston

    BK polyomavirus (BKV) is a significant infection affecting renal transplant recipients. Previous data suggests possible activity of fluoroquinolones against BKV, although their role in preventing…
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