2013 American Transplant Congress
Protection from Prolonged Cold Ischemia (CI) of Several Days Duration Is Mediated by Anti-Apoptotic phosphoBAD during Hibernation
Donor kidney cold (4°C) ischemia (CI) of >30 hrs is associated with increased apoptosis of renal tubular epithelial cells (RTEC) and is an important cause…2013 American Transplant Congress
Renal Transplant Recipients with Positive Donor Specific Antibodies Maintain Stable Graft Function with Mycophenolic Acid Escalation
Background: Donor-specific HLA antibody (DSA) formation in post-renal transplant patients is associated with chronic rejection and graft failure. IgG3 DSA has been associated with poorer…2013 American Transplant Congress
Molecular Landscape of Antibody-Mediated Rejection: Reading Endothelial Cell Biology in the Microcirculation, The
University of Alberta, Edmonton, Canada
Because experimental models are lacking, the recent emergence of a molecular definition of antibody-mediated rejection (ABMR) presents opportunities to characterize the mechanisms operating in ABMR.…2013 American Transplant Congress
Autosomal Dominant Polycystic Kidney Disease (PKD) Evaluated for Renal Transplantation. A Single Center Experience at Emory Transplant Center
Department of Nephrology, Emory University Hospital, Atlanta, GA
PKD is the fourth cause of ESRD and accounts for 13% of yearly kidney transplants in the US. Our goal is to use an established…2013 American Transplant Congress
Novel Diagnostic Serum Protein Panels for Transplant Injury Monitoring
California Pacific Medical Center, San Francisco
Background: Kidney transplantation is the best treatment option for end stage kidney failure. However, long term management for a prolonged life of these transplanted organs…2013 American Transplant Congress
Is KDPI Accurate in Predicting Outcomes Associated with Utilization of Single Pediatric Donor Kidneys?
Surgery, New York-Presbyterian Hospital/Weill Cornell Medical College, New York, NY
Background The Kidney Donor Profile Index (KDPI) is an excellent tool to provide the clinician with a more comprehensive and continuous estimate of donor quality.…2013 American Transplant Congress
Features of Antibody-Mediated Rejection (AMR) in Early and Late Protocol and Indication Renal Allograft Biopsies
Depts of Medicine, ; Pathology, ; Surgery, University of Maryland, Baltimore, MD
The prevalence of serologic and histologic features of AMR in early and late biopsies and in association with graft fuction has not been well-recognized. We…2013 American Transplant Congress
Differing Characteristics of New-Onset Diabetes after Transplantation (NODAT) in African-American Compared to Non-African-American Kidney Recipients
Hospital of the University of Pennsylvania, Philadelphia, PA
Background: NODAT, a common 1st post-transplant year complication, is more prevalent in African-American recipients (AA). Risk factors for, and the clinical course of NODAT are…2013 American Transplant Congress
Efficacy and Safety of Everolimus Based Immunosuppression on De Novo Kidney Transplantation with 4 Years Follow-Up Especially in Protocol Biopsy Findings and Donor Specific Antibody Production
Purpose: The impact of everolimus (EVR) based immunosuppression in De Novo Kidney Transplantation was evaluated in clinical outcomes, protocol biopsies findings and donor specific antibody…2013 American Transplant Congress
Mechanisms of Intra-Graft Regulatory T Cell Suppressor Function
University of Pittsburgh School of Medicine, T.E. Starzl Transplantation Institute, Pittsburgh, PA
Regulatory CD4+ T cells (Treg) have the ability to migrate to allografts to exert their suppressor function and prevent rejection. However, the mechanisms of suppression…
American Transplant Congress abstracts