2022 American Transplant Congress
Donors’ Perceptions of Uterus Donation Motivations, Informed Consent and Value: A Qualitative Study of Dallas Uterus Transplant Study (duets) Participants
*Purpose: Clinical trials have demonstrated the feasibility and reproducibility of uterus transplantation (UTx) to treat absolute uterine factor infertility. Successful live births have resulted from…2022 American Transplant Congress
Improving Value Delivery in Compatible Living Donor Kidney (CLD) Transplant Through Zero-Low Eplet Mismatch via National Kidney Registry (NKR)
1Intermountain Medical Center, Murray, UT, 2CareDX, South San Francisco, CA
*Purpose: Despite advances in diagnostics and therapeutics, kidney allograft survival rates have not increased considerably. Kidney For Life (KFL) through NKR aims to increase access…2022 American Transplant Congress
Performance of Updated Estimated Glomerular Filtration Rate Equations in Black Living Kidney Donor Candidates
Cleveland Clinic, Cleveland, OH
*Purpose: New estimated glomerular filtration rate (eGFR) equations using serum creatinine (Cr) and/or cystatin C (CysC) have been derived to eliminate adjustment by perceived Black…2022 American Transplant Congress
Recoverability of Diabetic Nephropathy of Donor Kidney After Kidney Transplantation
Samsung Medical Center, Seoul, Korea, Republic of
*Purpose: The natural course of diabetic donors on the outcome of kidney transplantation (KT) is controversial. The aim of this study was to analyze the…2022 American Transplant Congress
Spatially Resolved Molecular Profiling of Endothelial Cells in Antibody-Mediated Kidney Transplant Rejection
UAB School of Medicine, Birmingham, AL
*Purpose: Endothelial cells are key targets of alloimmune injury in antibody-mediated rejection (ABMR), but are challenging to study in situ using high-throughput methods. We aimed…2022 American Transplant Congress
VCA Waiting List and Transplant Trends and Challenges in the US
1Research, UNOS, Richmond, VA, 2Office of the CMO, UNOS, Richmond, VA
*Purpose: VCA transplantation has grown and changed, encountering challenges such as scarce funding sources and the COVID-19 pandemic.*Methods: The OPTN cohort includes 105 candidates listed…2022 American Transplant Congress
Donor App Increases Awareness and Overall Rates of Living Kidney Donation
*Purpose: The rate of living donor kidney transplants (LDKTs) performed has declined overall regardless of race. Studies show that web-based tools increase access to living…2022 American Transplant Congress
RNA Sequencing Profiling of Pretransplant Blood Identified Variant Allele Specific Expression of Leukocyte Immunoglobulin-Like Receptors (LILRs) Genes Associated with Graft Loss in Kidney Transplant Recipients
*Purpose: The RNA sequencing has the possibility of detecting overall gene expression as well as allele-specific expression. Here, we reported a study of genome-wide allele…2022 American Transplant Congress
Detection of Alloreactive CD8+ T Cell Responses and the Immunopeptidome That Elicits Their Activation
*Purpose: T cell-mediated rejection results in graft dysfunction and contributes to premature failure. Due to the complexity of the TCR:pMHC interaction, prediction of alloreactive T…2022 American Transplant Congress
Very Small Pediatric Donors May Help Address the Sex Disparity in Access to Kidney Transplantation
UC Davis Medical Center, Sacramento, CA
*Purpose: Women with end-stage renal disease have lower access to deceased donor kidney transplantation than men. Expanding the donor pool to include kidneys from very…
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