2013 American Transplant Congress
Optimization of the Coating of Pancreatic Islets with T Regulatory Cells in the Novel Immunoprotective Approach
Aim. T regulatory cells (Tregs) possess immunosuppressive properties and can serve as an effective therapy in transplantation. Recently, we have shown that Tregs can be…2013 American Transplant Congress
Tuning the OPTN's KPD Optimization Algorithm To Incentivize Centers To Enter Their "Easy-to-Match" Pairs
Background: Currently, priority points are awarded in the OPTN Kidney Paired Donation Pilot Program's (KPDPP) optimization algorithm as follows: zero mismatch (200 pts), highly sensitized…2013 American Transplant Congress
Viral Determinants of Pathogen Induced Alloantibody Production
Emory Transplant Center, Atlanta
Background: The appearance of alloantibody can initiate the onset of rapid and destructive antibody-mediated rejection (AMR) or have no demonstrable acute effects. The factors determining…2013 American Transplant Congress
CMV Serostatus Correlation with Early Kidney Allograft Transcriptome Change in the GOCAR Cohort
Identifying transcriptional change in renal allografts infected with Cytomegalovirus (CMV) may be important in understanding CMV effects on graft rejection and injury.We examined transcriptional profiles…2013 American Transplant Congress
Late Antibody-Mediated Rejection (AMR) after Kidney Transplantation
INTRODUCTION: Late AMR can develop at any time post kidney transplantation and represents a major challenge.OBJECTIVE: To characterize a series of kidney transplant recipients with…2013 American Transplant Congress
Bortezomib Impacts T-Cell Signaling and Regulatory Pathways
Med. Univ South Carolina, Charleston; Cleveland Clinic, Cleveland; Emory University, Atlanta
Introduction/ Aims: Bortezomib (PS-341), a selective 26S proteasome inhibitor has been used to treat antibody mediated rejection (AMR) among allograft recipients. The efficacy of Bortezomib…2013 American Transplant Congress
Outcomes in Lung Transplantation: The RIFLE Classification Optimizes the Predictive Utility of Post-Transplant Acute Kidney Injury as a Determinant of Early and Late Outcomes
The purpose of this study is to compare two methods of classifying acute kidney injury (AKI), the Risk, Injury, Failure, Loss, End stage (RIFLE) and…2013 American Transplant Congress
Rate and Causality of Thirty-Day Readmissions Following Renal Transplantation
Glickman Urological & Kidney Institute, Cleveland Clinic, Cleveland, OH
Introduction: The Affordable Care Act, added to the Social Security Act, established the Hospital Readmission Reduction Program which will penalize hospitals with excessive 30-day readmissions…2013 American Transplant Congress
Single Center Experience with Long-Term Prospective BK Monitoring in Renal Transplantation
Prospective screening for BK viremia (BKV) in renal transplant recipients (RTR) may allow earlier detection of BKV reactivation and prevent BKV nephropathy (BKVN). However, utility…2013 American Transplant Congress
Pivotal Circulating Antibody Panel for Pre-Transplant Prediction of FSGS Recurrence after Kidney Transplantation, A
Introduction: Recurrence of focal segmental glomerulosclerosis (rFSGS) after kidney transplantation leads to graft loss. The identity of the involved antibodies and specific immunogenic epitopes remains…