2013 American Transplant Congress
Normothermic Oxygenated Machine Preservation Reduces Reperfusion Injury of DCD Livers but Seems Less Useful in Standard Heart-Beating Livers: A Comparative Study in a Rat Model
Background: Normothermic oxygenated machine perfusion (NMP) may reduce ischemia/reperfusion (I/R) injury in livers derived from donation after cardiac death (DCD) donors. Aim of this study…2013 American Transplant Congress
Removal of CD39+ T Cells Uncovers a Population of Col V Specific, CD39- Responder T Cells in Normal, Healthy Individuals
Transplant Surgery, University of Wisconsin, Madison, WI
We and others have reported that autoimmunity to the self antigen Collagen V (ColV) after lung transplantation, is strongly correlated with the development of Bronchiolitis…2013 American Transplant Congress
Dual Nanoporous Encapsulation and Local Exenatide Delivery Improves Islet Viability
The Ohio State University, Columbus, OH
Transplantation of pancreatic islets is recognized as a potential curative therapy for TIDM; however, islets are extremely susceptible to the mechanical, hypoxic and immunologic stresses…2013 American Transplant Congress
Tissue Proteomics Reveals Protein Differences Associated with Allograft Cellular Rejection
Purpose: To investigate protein differences in renal allografts to provide insight into the pathophysiology of cellular rejection. The objective is to determine which proteins are…2013 American Transplant Congress
Impact of Seasonal Influenza Immunization (Influenza+ H1N1) on HLA Antibodies and Kidney Allograft Function
Indiana University School of Medicine, Indianapolis, IN
Seasonal influenza vaccine (influenza + H1N1) is recommended for all solid organ transplant patients. Vaccines have been implicated in changes to HLA antibody profile with…2013 American Transplant Congress
Medical Nonadherence as a Cause of Renal Allograft Failure: A Ten Year Single Center Retrospective Analysis
Annette C & Harold C Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX
Background: Despite the advent of modern immunosuppression, long term renal allograft outcomes have remained relatively unchanged. In the renal transplant population, medical nonadherence is a…2013 American Transplant Congress
Role of PI3K/AKT and Autophagy in the Protective Effect of Fasting Against Liver Ischemia Reperfusion Injury in Mice, The
Background and aim: Preoperative fasting is known to attenuate liver ischemia reperfusion injury (IRI). However, the exact mechanism behind this protective effect is unknown. This…2013 American Transplant Congress
In Vitro Characterization of Vertebral Bone Marrow Used for Immunomodulation in Hand Transplantation
Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD
Purpose: Peri-operative cadaveric donor vertebral body bone marrow (VBBM) infusion has shown promising immunomodulatory effects (graft maintenance on low-dose tacrolimus monotherapy) in clinical trials of…2013 American Transplant Congress
Pre-Liver Transplant (LT) Proteinuria Is Not an Absolute Indication for Simultaneous Liver Kidney Transplantation (SLK)
Transplantation, Mayo Clinic, Jacksonville, FL
LT candidates with proteinuria and renal dysfunction are often considered for SLK. Methods: 39 LT candidates with 24-hr urine protein >150 mg/dl and renal dysfunction…2013 American Transplant Congress
Cause of Progression in Failing Kidney Transplants with Diseases Is Parenchymal Injury, Not Fibrosis, The
Alberta Transplant Applied Genomics Centre, University of Alberta, Edmonton, AB, Canada
We previously reported that human kidney transplants with early acute kidney injury (AKI) biopsied in the first six weeks express transcripts indicating injury-repair (IRRATs). Expression…
American Transplant Congress abstracts