ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    National Sharing of ECD Kidneys Is Justified, Even in the Face of Prolonged CIT

    J. Gill, J. Dong, O. Johnston, J. Gill, D. Landsberg

    University of British Columbia, Vancouver, Canada

    Current kidney allocation in the US includes national sharing of ECD kidneys in cases of 0 HLA- A- B DR mismatches. Concerns regarding prolonged CIT…
  • 2013 American Transplant Congress

    Decreasing Estimated Glomerular Filtration Rate (eGFR) Is Associated with an Increasing Risk of Hospitalization in the First Year Post Renal Transplantation

    Y. Afshar, F. Keong, S. Sekar, J. Binongo, R. Chowdhury, S. Pastan, R. Patzer

    Rollins School of Public Health, Emory University, Atlanta; Department of Medicine, Renal Division, Emory University, Atlanta, GA; Emory Transplant Center, Atlanta

    Background: A decrease in renal function is associated with an increased risk of cardiovascular disease, graft loss and mortality following renal transplantation. It is unclear…
  • 2013 American Transplant Congress

    Mouse Models That Fully Reproduce Human Acute and Chronic Antibody-Mediated Kidney Transplant Rejection

    A. Chow, J. Pearcey, T. Ho, A. Raghuveer, P. Kuttikat, L. Zhu, B. Sis

    University of Alberta, Edmonton, Canada

    Antibody-mediated rejection (ABMR) is a major cause of late kidney transplant failure. Until now, lack of relevant small animal models of pure antibody-mediated rejection has…
  • 2013 American Transplant Congress

    Heterogeneity in Transcripts Induced in Implantation Biopsies: Distinguishing Preexisting Injury from Acute Phase Response

    K. Famulski, D. de Freitas, J. Reeve, P. Halloran

    Alberta Transplant Appled Genomics Centre, University of Alberta, Edmonton, AB, Canada; Manchester Royal Infirmary, Manchester, United Kingdom

    Human kidney transplants with early acute kidney injury (AKI) express transcripts indicating the injury-repair process (IRRATs). Expression of IRRATs correlated with delayed graft function (DGF)…
  • 2013 American Transplant Congress

    Predicting Digest Tissue Volume of Chronic Pancreatitis Pancreas Intended for Islet Auto-Transplantation (IAT)

    M. Tiwari, J. Wilhelm, M. Bellin, S. Soltani, G. Loganathan, T. Dunn, S. Chinnakotla, S. Vickers, T. Pruett, G. Beilman, D. Sutherland, B. Hering, A. Balamurugan

    Schulze Diabetes Institute; Dept. of Surgery, Uni. of Minnesota, Minneapolis

    Total pancreatectomy with islet autotransplantation is a major surgical procedure for which it is desirable to minimize the total transplanted tissue volume (TV) and the…
  • 2013 American Transplant Congress

    Steroid Avoidance with Alemtuzumab Induction and Tacrolimus Monotherapy Gives Similar Outcomes to Basiliximab Induction with Tacrolimus / Mycophenolate Maintenance at Three Years

    M. Welberry Smith, A. Cherukuri, C. Newstead, A. Lewington, N. Ahmad, K. Menon, S. Pollard, P. Prasad, S. Tibble, E. Giddings, R. Baker

    Department of Renal Medicine and Transplantation, St. James' University Hospital, Leeds, Yorkshire, United Kingdom; Department of Transplant Surgery, St. James' University Hospital, Leeds, Yorkshire, United Kingdom; Department of Histopathology, St. James' University Hospital, Leeds, Yorkshire, United Kingdom

    A randomised controlled trial comparing two steroid avoidance regimes was conducted in our centre from December 2006 to November 2010. Alemtuzumab induction followed by tacrolimus…
  • 2013 American Transplant Congress

    Subclinical EBV and CMV Viremia Is Significantly Associated with the Development of Interstitial Fibrosis and Tubular Atrophy (IF/TA) in Pediatric Renal Transplant Recipients

    S. Avasare, R. Ettenger, D. Gjertson, D. Puliyanda, E. Tsai

    Pediatric Nephrology, UCLA-David Geffen School of Medicine, Los Angeles, CA; Pathology and Laboratory Medicine - Immunogenetics Center, UCLA-David Geffen School of Medicine, Los Angeles, CA; Pediatric Nephrology, Cedars Sinai Medical Center, UCLA-David Geffen School of Medicine, Los Angeles, CA

    Purpose:The leading cause of pediatric kidney transplant loss is chronic renal allograft dysfunction (CRAD). Currently, the etiology of CRAD is thought to be multi-factorial. While…
  • 2013 American Transplant Congress

    Understanding Racial Disparity in Living Donor Kidney Transplantation

    R. Garcia-Roca, N. Choudhury, I. Tzvetanov, H. Jeon, J. Oberholzer, E. Benedetti

    Division of Transplantation, University of Illinois at Chicago, CHicago, IL

    BACKGROUND: There is a large ethnical disparity in the rate of living kidney donation. We analyzed possible causes of this difference.METHOD: We performed a single-center…
  • 2013 American Transplant Congress

    In Vivo Interaction between ATG and IVIg May Decrease the Efficacy of Antibody Mediated Rejection Treatment

    C. Kuriakose, P. Warner, K. Nelson, N. Kieran, R. Bakthavatsalam, C. Davis, N. Leca

    Division of Nephrology, University of Washington, Seattle; Puget Sound Blood Center, Seattle; Division of Transplant Surgery, University of Washington, Seattle

    Treatment of antibody mediated rejection(AMR) is not standardized. Anti-thymocyte globulin(ATG) is commonly used in combination with intravenous immunoglobulin(IVIg) and plasmapheresis(Px). Our in vitro data show…
  • 2013 American Transplant Congress

    Association of B Cell Population in Splenic Histology of ABO Incompatible Kidney Transplantation and One-Year Graft and Recipient Survival, The

    I. Tzvetanov, L. Bejarano-Pineda, S. Setty, A. Harbhajanka, A. Khan, H. Jeon, R. Garcia-Roca, J. Oberholzer, E. Benedetti

    Department of Surgery, University of Illinois Hospital & Health Sciences System, Chicago, IL; Department of Pathology, Illinois Hospital & Health Sciences System, Chicago, IL

    Purpose: To evaluate the association of plasma cell population (PCs) in splenic histology of ABO incompatible (ABO-i) kidney transplant recipients and one year graft and…
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