2013 American Transplant Congress
Eculizumab Efficacy in aHUS Pts with Progressing TMA, with or without Prior Renal Transplant
INTRODUCTION: Ongoing aHUS post renal transplant leads to graft failure within 1 yr in 60% of patients (pts).1 Case reports suggest eculizumab (ecu) prevents ongoing…2013 American Transplant Congress
Transplant Dermatology Is an Essential Part of Transplant Care: Report of First Year Experience
Background: It has been well documented that patients who have undergone organ transplantation have a higher incidence of new skin cancers and that this risk…2013 American Transplant Congress
Pathogenesis of TIM-4 Mediated Phagocytosis in Mouse Liver Ischemia and Reperfusion Injury (IRI), The
Dept of Surgery, Dumont-UCLA Liver Transplant Center, Los Angeles, CA
Background: Macrophages are critical hematopoietic cells in IR-mediated liver inflammation and in the acquisition of hepatic homeostasis. Macrophage TIM-4 expression regulates the engulfment of apoptotic/necrotic…2013 American Transplant Congress
Gastric Fundoplication To Prevent Reflux Symptoms in Stomach Transplantation
Transplant Division, Dept of Surgery, Indiana University School of Medicine, Indianapolis, IN
IntroductionTransplantation of the stomach occurs as part of a multivisceral or modified multivisceral transplant. Severe gastroesophageal reflux (GER) is a common complication associated with stomach…2013 American Transplant Congress
Presence of Preformed IgG3 DSA Identifies Patients at Higher Risk of Early Rejection in Liver Transplantation
Aim: to examine the impact of preformed IgG3 donor-specific HLA antibodies (DSA) in early acute rejection after liver transplantation (LT).Methods: We analyzed 1271 adult LT…2013 American Transplant Congress
Incidence, Risk Factors, and Response Rate to Initial Therapy for Clostridum Difficile in Solid Organ Transplant Recipients
University of North Carolina, Chapel Hill, NC
Clostridium difficile Infection (CDI) has been shown to occur at a higher rate in the solid organ transplant (SOT) population compared to the general hospitalized…2013 American Transplant Congress
First Kidney Graft Survival Is Associated with Second Kidney Transplant Outcomes in Pediatric Patients with Highly Recurrent Disease
Intro: Pediatric kidney transplant(KTx) patients with FSGS/SLE/HUS(Focal Segmental Glomerulosclerosis/Lupus/Hemolytic Uremic Syndrome) may experience recurrent disease which negatively impacts graft survival. We examined whether first graft…2013 American Transplant Congress
Severity of Cardiac Allograft Vasculopathy after Heart Transplant Is Reduced with Proliferation Signal Inhibitors
Cedars-Sinai Heart Institute, Los Angeles, CA
Background: The multicenter randomized trials of everolimus have demonstrated a significant reduction in 1st Year maximal intimal thickness. It has been demonstrated from a validation…2013 American Transplant Congress
Transplant Dermatology Referrals Result in Unexpected Non-Malignant Diagnoses
Drexel University College of Medicine, Philadelphia, PA
Background:Although the primary focus of transplant dermatology care is the early detection and treatment of skin cancers in an immunocompromised population, a wide variety of…2013 American Transplant Congress
Neuropeptide PACAP Mediated Autophagy in Mouse Liver Ischemia and Reperfusion Injury: Modulation Via cAMP/PKA-CREB-KLF4 Pathway
Dept of Surgery, Dumont-UCLA Liver Transplant Center, Los Angeles, CA
Background: Autophagy (self-eating) represents a critical mechanism for cellular homeostasis and survival response to the stress. We have shown that neuropeptide PACAP (Pituitary Adenylate Cyclase-Activating…