ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Ten-Year Experience in Pediatric Renal Transplant Using Thymoglobulin Induction and Steroid Minimization

    J. Warejko, S. Hmiel

    Pediatrics, St. Louis Children's Hospital, St. Louis, MO; Division of Pediatric Nephrology, Washington University in St. Louis, St. Louis, MO

    Introduction: Our center has offered steroid minimized, thymoglobulin induction to our pediatric renal transplant patients for the last 10 years. Steroid minimization or avoidance in…
  • 2013 American Transplant Congress

    Safety and Effectiveness of Valganciclovir for Cytomegalovirus Prophylaxis in Solid Organ Transplant Patients on Hemodialysis

    U. Wang, A. Yang, M. Dong, S. Busque

    Pharmacy, Stanford Hospital and Clinics, Palo Alto, CA; Multiorgan Transplant, Stanford Hospital and Clinics, Palo Alto, CA

    Purpose: Valganciclovir is used for the prevention of cytomegalovirus (CMV) infections in solid organ transplant (SOT) patients. Currently, no dosing recommendation is available for patients…
  • 2013 American Transplant Congress

    DAP12 Deficiency in Liver Allografts Enhances Donor DC Migration, Host Alloimmunity and Breaks Liver Transplant Tolerance

    O. Yoshida, S. Kimura, N. Murase, A. Thomson

    Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA; Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA

    Background: Fully MHC-mismatched mouse liver allografts are accepted without immunosuppressive therapy and induce donor-specific tolerance. Liver dendritic cells (DC) exhibit an immature phenotype that may…
  • 2013 American Transplant Congress

    Telomere Length of Living Kidney Donors and Recipients and Chronic Graft Dysfunction in Kidney Transplants

    W. Oetting, W. Guan, W. Wildenbush, P. Jacobson, A. Matas, A. Israni, DeKAF Investigators

    University of Minnesota, Minneapolis, MN

    Background: Telomeres consist of multiple copies (100s to 1000s) of short (6 nucleotide) repeats at the end of all chromosomes, playing a protective role against…
  • 2013 American Transplant Congress

    Protective Effect of a FDA-Approved Intralipid on Kidney Ischemia/Reperfusion Injury

    Q. Ye, L. Liu, Y. Wu, T. Hitchens, F. Yhe, B. Barbe, W. Li, C. Ho

    Pittsburgh NMR Center for Biomedical Research and Department of Biological Sciences, Carnegie Mellon University, Pittsburgh

    BACKGROUND: Ischemia/reperfusion injury (IRI) resulting from the procedure of transplantation has a negative impact on both short- and long- time graft survival. Early activation of…
  • 2013 American Transplant Congress

    Rapamycin-Resistant mTORC1 Regulates Dendritic Cell B7-H1 Expression That Acts in Synergy with IL-1β To Promote Regulatory T Cell Induction

    B. Rosborough, D. Raich-Regue, B. Matta, K. Lee, M. Boothby, H. Turnquist, A. Thomson

    Surgery, Starzl Transplant Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA; Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN

    Introduction: The mammalian Target of Rapamycin (mTOR) is targeted clinically with rapamycin (RAPA) to prevent allograft rejection. mTOR functions in two mTOR-containing complexes, – mTOR…
  • 2013 American Transplant Congress

    Is the Obesity Epidemic in the United States Driving the Lack of Growth of Live Kidney Donation?

    D. Moore, I. Feurer, L. Dageforde, E. Zavala, D. Moore

    Division of Kidney/Pancreas Transplantation, Vanderbilt University Medical Center, Nashville, TN

    Introduction: The prevalence of obesity in the United States has increased significantly over the last twenty years and nearly one-third of adults are obese. The…
  • 2013 American Transplant Congress

    Prolonged Cold Ischemia Impairs Outcome in Recipients of Donation after Cardiac Death (DCD) Kidney Transplants Despite Machine Perfusion

    S. Paloyo, J. Sageshima, G. Ciancio, L. Chen, A. Mattiazzi, G. Guerra, W. Kupin, D. Roth, S. Ganz, G. Burke III

    Miami Transplant Institute, University of Miami Miller School of Medicine, Miami

    Introduction: The impact of prolonged cold ischemia time (CIT) on kidney grafts donated after circulatory death (DCD) remains unclear when grafts were preserved by hypothermic…
  • 2013 American Transplant Congress

    Immunosuppressive Property of Liver Sinusoidal Endothelial Cells Is Impaired in Small-for-Size Grafts and Restored by Attenuating Portal Hypertension, The

    S. Hashimoto, T. Onoe, Y. Tanaka, Y. Igarashi, H. Ohdan

    Department of Surgery, Hiroshima University, hiroshima, Japan

    Background:We have previously shown that the accelerated anti-donor immune response is related to the portal hypertension (PH) that develops after living-donor liver transplantation (LDLT), especially…
  • 2013 American Transplant Congress

    miRNA Signature Associated with Induced Tolerance in Liver Allografts, The

    L. Wei, K. Ruster, C. Esquivel, O. Martinez, S. Krams

    Department of Surgery/Division of Abdominal Transplantation, Stanford University, Stanford, CA

    Although the liver is less immunogenic than other solid organs, most liver transplant recipients receive lifelong immunosuppression. A subset of liver recipients may be operationally…
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