2013 American Transplant Congress
Ten-Year Experience in Pediatric Renal Transplant Using Thymoglobulin Induction and Steroid Minimization
Introduction: Our center has offered steroid minimized, thymoglobulin induction to our pediatric renal transplant patients for the last 10 years. Steroid minimization or avoidance in…2013 American Transplant Congress
Safety and Effectiveness of Valganciclovir for Cytomegalovirus Prophylaxis in Solid Organ Transplant Patients on Hemodialysis
Purpose: Valganciclovir is used for the prevention of cytomegalovirus (CMV) infections in solid organ transplant (SOT) patients. Currently, no dosing recommendation is available for patients…2013 American Transplant Congress
DAP12 Deficiency in Liver Allografts Enhances Donor DC Migration, Host Alloimmunity and Breaks Liver Transplant Tolerance
Background: Fully MHC-mismatched mouse liver allografts are accepted without immunosuppressive therapy and induce donor-specific tolerance. Liver dendritic cells (DC) exhibit an immature phenotype that may…2013 American Transplant Congress
Telomere Length of Living Kidney Donors and Recipients and Chronic Graft Dysfunction in Kidney Transplants
University of Minnesota, Minneapolis, MN
Background: Telomeres consist of multiple copies (100s to 1000s) of short (6 nucleotide) repeats at the end of all chromosomes, playing a protective role against…2013 American Transplant Congress
Protective Effect of a FDA-Approved Intralipid on Kidney Ischemia/Reperfusion Injury
BACKGROUND: Ischemia/reperfusion injury (IRI) resulting from the procedure of transplantation has a negative impact on both short- and long- time graft survival. Early activation of…2013 American Transplant Congress
Rapamycin-Resistant mTORC1 Regulates Dendritic Cell B7-H1 Expression That Acts in Synergy with IL-1β To Promote Regulatory T Cell Induction
Introduction: The mammalian Target of Rapamycin (mTOR) is targeted clinically with rapamycin (RAPA) to prevent allograft rejection. mTOR functions in two mTOR-containing complexes, mTOR…2013 American Transplant Congress
Is the Obesity Epidemic in the United States Driving the Lack of Growth of Live Kidney Donation?
Division of Kidney/Pancreas Transplantation, Vanderbilt University Medical Center, Nashville, TN
Introduction: The prevalence of obesity in the United States has increased significantly over the last twenty years and nearly one-third of adults are obese. The…2013 American Transplant Congress
Prolonged Cold Ischemia Impairs Outcome in Recipients of Donation after Cardiac Death (DCD) Kidney Transplants Despite Machine Perfusion
Miami Transplant Institute, University of Miami Miller School of Medicine, Miami
Introduction: The impact of prolonged cold ischemia time (CIT) on kidney grafts donated after circulatory death (DCD) remains unclear when grafts were preserved by hypothermic…2013 American Transplant Congress
Immunosuppressive Property of Liver Sinusoidal Endothelial Cells Is Impaired in Small-for-Size Grafts and Restored by Attenuating Portal Hypertension, The
Department of Surgery, Hiroshima University, hiroshima, Japan
Background:We have previously shown that the accelerated anti-donor immune response is related to the portal hypertension (PH) that develops after living-donor liver transplantation (LDLT), especially…2013 American Transplant Congress
miRNA Signature Associated with Induced Tolerance in Liver Allografts, The
Department of Surgery/Division of Abdominal Transplantation, Stanford University, Stanford, CA
Although the liver is less immunogenic than other solid organs, most liver transplant recipients receive lifelong immunosuppression. A subset of liver recipients may be operationally…