2013 American Transplant Congress
Effects of Viral Infection on Chronic Anti-Mediated Rejection, The
Emory Transplant Center, Atlanta
[Background] Despite a 50% decline in acute rejection over the past 10 years, antibody-mediated injury has been identified as perhaps the leading cause of chronic…2013 American Transplant Congress
Donor Comorbidities Rather Than Age Alone Determine Recipient Outcomes in "SCD" Kidney Transplants
The Transplant Institute, Henry Ford Hospital, Detroit, MI
Deceased donor (DD) pool has been expanded with kidneys that have wide-ranging functional vitality and pathologic features stemming from increasing incidence of metabolic syndrome. To…2013 American Transplant Congress
CTLA-4 Ig Prevents Chronic Antibody-Mediated Rejection
Emory Transplant Center, Atlanta
[Background] Chronic rejection of organ transplants remains an unsolved problem in the field of transplantation. Humoral immunity, typically manifesting as alloantibody, is increasingly recognized as…2013 American Transplant Congress
Combined Liver-Kidney Transplantation: Simultaneous Versus Delayed Transplantation of the Kidney Graft
Transplant Division, Department of Surgery, Indiana University School of Medicine, Indianapolis, IN
Purpose: Patients requiring combined liver and kidney transplantation (LK) are at risk for worse outcomes because of severity of illness and complexity of the procedure.…2013 American Transplant Congress
Rapamycin Enhances Early Alloantibody Production by Hampering the Homeostatic Proliferation of Regulatory T Cells
Emory Transplant Center, Atlanta; Department of Pathology, Emory University, Atlanta
[Background] Antibody-mediated chronic rejection is one of the main obstacles to achieving long-term success of transplant. We demonstrated that alemtuzumab induction with rapamycin maintenance therapy…2013 American Transplant Congress
Subclinical Recurrent Lupus Nephritis: A Clinicopathologic Study
BackgroundThe frequency and significance of recurrent lupus nephritis (LN) is unclear. We evaluated the features of subclinical recurrent LN seen on early posttransplant biopsies and…2013 American Transplant Congress
True MELD Score Is Associated with HCC Patient Outcomes after Liver Transplant
Introduction:Patients with in-criteria HCC listed for liver transplantation(OLT) receive exception MELD scores(EM) not adjusted for disease severity unless the calculated, true MELD score(TM) exceeds the…2013 American Transplant Congress
Role of Innate and Adaptive Immunity in Survival and Neurogenesis of Neural Progenitor Cell Grafts, The
Surgery, Stanford University SOM, Stanford, CA; Neurosurgery, Stanford University SOM, Stanford, CA
Neural Progenitor Cells (NPC) are multipotent progenitors found within the brain that differentiate into neurons, oligodendrocytes, and astrocytes. Transplantation of NPC has been proposed as…2013 American Transplant Congress
Lung Allograft Tolerance in Non-Human Primates Via Establishment of Stable Mixed Hematopoietic Chimerism
Transplantation tolerance of kidney allografts has been achieved in both non-human primates (NHPs) and patients using a non-myeloablative conditioning regimen, costimulation blockade, and infusion of…2013 American Transplant Congress
Evidence for Decreased Cellular and Humoral Renal Allograft Rejection in Combined Liver-Kidney Transplants
Combined liver-kidney transplantation (CLKT) has been widely thought to have an immunoprotective effect on the kidney. However, detailed studies are lacking. The goal of this…
American Transplant Congress abstracts