2013 American Transplant Congress
Pancreas Transplantation: Personal Factors Associated with Good and Poor Post-Transplant Adaptive Response
Notable differences in patient adaptation after pancreas transplant cause some to thrive and return to independent living, while others struggle with emotional and social problems.…2013 American Transplant Congress
Graft Loss Rates after Donation after Cardiac Death (DCD) Liver Donation Are Severely Underestimated
Introduction: Organs from DCD donors, particularly livers, have been shown to have outcomes that are inferior to those from donation after brain death (DBD) donors…2013 American Transplant Congress
Accelerated Hepatic Fibrosis after Renal Transplantation: Long-Term Outcomes in HCV+ Patients
Surgery, Division of Transplantation, University of Maryland, Baltimore, MD
Introduction: It has been demonstrated that hepatitis C+ (HCV+) patients with renal failure benefit from kidney transplantation despite having decreased graft survival compared to HCV-…2013 American Transplant Congress
Monocyte Affinity for Donor Antigen Predicts Acute Cellular Rejection (ACR) after Intestinal or Liver Transplantation (ITx, LTx)
Background: Rejection-prone intestine allografts demonstrate CD14+monocyte-rich infiltrates immediately after reperfusion, suggesting that monocytes are capable of allorecognition akin to adaptive immunity. Purpose: To evaluate whether…2013 American Transplant Congress
Impact of Paired Exchange on Living Donor Kidney Transplantation: A Center Level Analysis, The
Univeristy of British Columbia, Vancouver, Canada
Although the number of living donor paired exchange (LDPE) kidney transplants increased 1000 fold between 2005-10, the total number of living donor kidney transplants (LDTx)…2013 American Transplant Congress
(Mis)use of Organs: Donation after Cardiac Death Donors Are Not Fulfilling the Mandate, The
Introduction: The discrepancy between organ availability and the demands of a growing waiting list has fuelled the need for ways to increase the organ supply.…2013 American Transplant Congress
CD4+ T Cell Differentiation and Belatacept Resistant Rejection
Emory University, Atlanta, GA; Bristol-Myers Squibb, Princeton, NJ
Purpose: T cells with a memory phenotype mediate costimulation blockade (CoB) resistant rejection (RR), and early CoBRR has been seen in patients on belatacept-based immunosuppression.…2013 American Transplant Congress
Burden of OPTN Data Submission: Far More Than Estimated
Northwestern University, Chicago, IL; University of California, Davis, Sacromento, CA
Background: The United Network for Organ Sharing (UNOS) holds an exclusive federal contract as the Organ Procurement and Transplantation Network (OPTN) to allocate deceased donor…2013 American Transplant Congress
Targeting of mTORC2 in DC Elicits an Enhanced Pro-Inflammatory Profile and Th17 Alloresponse
Mammalian target of rapamycin (mTOR) is an important, yet poorly understood integrative kinase that regulates immune cell function. mTOR functions in two independent complexes,- mTOR…2013 American Transplant Congress
French Uncontrolled Donors after Circulatory Arrest (Udcd) Program for Kidney Transplantation: Procurement Procedure Efficiency and 3-Month Survival Results
The national protocol for the uDCD program restricts the no flow period to <30 min and the total warm ischemia time (WIT) to <150 min.…