ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Pancreas Transplantation: Personal Factors Associated with Good and Poor Post-Transplant Adaptive Response

    P. Scott, A. Krause, G. Samiran, T. Taber, J. Fridell

    Occupational Therapy, Indiana University, Indianapolis, IN; Department of Family Medicine and Public Health Sciences, Wayne State University of Medicine, Detroit, MI; Department of Medicine, Indiana University Health/Indiana University School of Medicine, Indianapolis, IN

    Notable differences in patient adaptation after pancreas transplant cause some to thrive and return to independent living, while others struggle with emotional and social problems.…
  • 2013 American Transplant Congress

    Graft Loss Rates after Donation after Cardiac Death (DCD) Liver Donation Are Severely Underestimated

    M. DebRoy, G. Klintmalm

    Surgery, Division of Transplantation, UT Southwestern Medical Center, Dallas, TX; Annette C and Harold C. Simmons Transplant Institute at Baylor University Medical Center, Dallas, TX

    Introduction: Organs from DCD donors, particularly livers, have been shown to have outcomes that are inferior to those from donation after brain death (DBD) donors…
  • 2013 American Transplant Congress

    Accelerated Hepatic Fibrosis after Renal Transplantation: Long-Term Outcomes in HCV+ Patients

    J. Scalea, R. Munivenkatappa, V. Whitlow, B. Neuman, S. Fayek, M. Cooper, B. Philosophe

    Surgery, Division of Transplantation, University of Maryland, Baltimore, MD

    Introduction: It has been demonstrated that hepatitis C+ (HCV+) patients with renal failure benefit from kidney transplantation despite having decreased graft survival compared to HCV-…
  • 2013 American Transplant Congress

    Monocyte Affinity for Donor Antigen Predicts Acute Cellular Rejection (ACR) after Intestinal or Liver Transplantation (ITx, LTx)

    C. Ashokkumar, M. Ningappa, B. Higgs, Q. Sun, R. Sindhi

    Transplant Surgery, University of Pittsburgh, Pittsburgh, PA; Transplant Surgery, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA

    Background: Rejection-prone intestine allografts demonstrate CD14+monocyte-rich infiltrates immediately after reperfusion, suggesting that monocytes are capable of allorecognition akin to adaptive immunity. Purpose: To evaluate whether…
  • 2013 American Transplant Congress

    Impact of Paired Exchange on Living Donor Kidney Transplantation: A Center Level Analysis, The

    J. Gill, C. Rose, J. Dong, O. Johnston, J. Gill, D. Landsberg

    Univeristy of British Columbia, Vancouver, Canada

    Although the number of living donor paired exchange (LDPE) kidney transplants increased 1000 fold between 2005-10, the total number of living donor kidney transplants (LDTx)…
  • 2013 American Transplant Congress

    (Mis)use of Organs: Donation after Cardiac Death Donors Are Not Fulfilling the Mandate, The

    M. DebRoy, G. Klintmalm

    Surgery, Division of Transplant Surgery, UT Southwestern Medical Center, Dallas, TX; Annette C. and Harold C. Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX

    Introduction: The discrepancy between organ availability and the demands of a growing waiting list has fuelled the need for ways to increase the organ supply.…
  • 2013 American Transplant Congress

    CD4+ T Cell Differentiation and Belatacept Resistant Rejection

    J. Espinosa, J. Cheeseman, A. Mehta, L. Stempora, R. Townsend, A. Kirk

    Emory University, Atlanta, GA; Bristol-Myers Squibb, Princeton, NJ

    Purpose: T cells with a memory phenotype mediate costimulation blockade (CoB) resistant rejection (RR), and early CoBRR has been seen in patients on belatacept-based immunosuppression.…
  • 2013 American Transplant Congress

    Burden of OPTN Data Submission: Far More Than Estimated

    K. Xu, L. Preczewski, G. McNatt, D. Ladner

    Northwestern University, Chicago, IL; University of California, Davis, Sacromento, CA

    Background: The United Network for Organ Sharing (UNOS) holds an exclusive federal contract as the Organ Procurement and Transplantation Network (OPTN) to allocate deceased donor…
  • 2013 American Transplant Congress

    Targeting of mTORC2 in DC Elicits an Enhanced Pro-Inflammatory Profile and Th17 Alloresponse

    D. Raich-Regue, B. Rosborough, K. Lee, M. Boothby, H. Turnquist, A. Thomson

    Department of Surgery and Department of Immunology, Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA; Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN

    Mammalian target of rapamycin (mTOR) is an important, yet poorly understood integrative kinase that regulates immune cell function. mTOR functions in two independent complexes,- mTOR…
  • 2013 American Transplant Congress

    French Uncontrolled Donors after Circulatory Arrest (Udcd) Program for Kidney Transplantation: Procurement Procedure Efficiency and 3-Month Survival Results

    C. Antoine, E. Savoye, L. Jacob, G. Cheisson, B. Riou, L. Badet, M. Videcoq, G. Strecker, M. Thuong, National Steering Committee Non Heart Beating Donors Group

    Biomedecine Agency, La Plaine Saint Denis, France; Department of Anesthesia and Critical Care, Saint Louis Hospital, Paris, France; Department of Anesthesia and Critical Care, Bicetre Hospital, Kremlin Bicetre, France; Emergency Department, La Pitié Salpêtrière Hospital, Pitié, France; Department of Transplantation, Edouard Herriot Hospital Group, Lyon, France; Department of Anesthesia and Critical Care, Hôtel-Dieu Hospital, Nantes, France; Department of Anesthesia and Critical Care, Huriez Hospital, Lille, France

    The national protocol for the uDCD program restricts the no flow period to <30 min and the total warm ischemia time (WIT) to <150 min.…
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