2013 American Transplant Congress
High Frequency of Valganciclovir Under- and Overdosing for CMV Prophylaxis after Renal Transplantation
Department of Nephrology, Charite-Universitätsmedizin Berlin CCM, Berlin, Germany
The correct valganciclovir (vgc) dose for CMV-prophylaxis depends on renal function as assessed by the Cockroft Gault formula (CG-eGFR) for patients (pts) after transplantation (Tx).We…2013 American Transplant Congress
Donor HSCs from the Bone Component of Vascularized Composite Allografts Migrate to Recipient Thymus and Differentiate to Mature T Cells
Introduction:Vascularized composite allografts (VCA) feature an inexhaustible source of donor HSCs, which under proper immunomodulation might be able to migrate into the recipients thymus and…2013 American Transplant Congress
Post-Transplant Complement Binding DSA: Higher Risk of Kidney Allograft Loss
Anti-HLA antibodies are a major obstacle to transplantation success. We hypothesized that the complement binding capacity of anti-HLA antibodies assessed in the recipient sera could…2013 American Transplant Congress
Killer Immunoglobulin-Like Receptor (KIR) Mismatches and KIR-HLA-C Interactions Do Not Affect Short Term Graft Function in Kidney Transplantation
Human Leucocyte Antigen (HLA) matching is an important factor in long term graft survival in kidney transplantations. Natural Killer (NK) cells with their MHC recognizing…2013 American Transplant Congress
Normothermic Acellular Ex Vivo Liver Perfusion (NEVLP): Development of a New Method for the Storage, Assessment, and Repair of Marginal Liver Grafts
We compared the novel normothermic acellular ex vivo liver perfusion (NEVLP) with conventional cold static organ preservation for livers retrieved after cardiac death.Methods: Pig livers…2013 American Transplant Congress
Optimizing Kidney Exchange with Transplant Chains: Theory and Reality
Computer Science Department, Carnegie Mellon University, Pittsburgh, PA
We explore the theoretical and empirical efficacy of long altruist-initiated chains in kidney exchange programs. Kidney exchange, where needy patients swap incompatible donors with each…2013 American Transplant Congress
Pattern of Utilization and Graft Outcomes of Patients Received Kidney Transplants from Deceased Donors < 4 Years, The
Kidneys from donors < 4 years remain underutilized because of the concerns of the recipient complications (bleeding, urine leak and graft thrombosis), and poor long-term…2013 American Transplant Congress
Comparison of Protein A-Immuno-Adsorption and Conventional Plasma Exchanges for Anti-HLA Desensitization
Nephrology, Dialysis, Transplantation, University Hospital, Saint-Etienne, France
Plasma exchanges therapy is traditionally part of anti-HLA desensitization strategies used in kidney transplantation. As compared to conventional techniques of plasma exchanges (PE) (plasma-centrifugation or…2013 American Transplant Congress
“Spontaneous” Reduction in Donor Specific Allo-Antibody (DSA) after Positive Cross Match Kidney Transplantation (+XMKTx) Is Associated with Improved Histology
Introduction.In a recent study (AJT,2011;11:2405), eculizumab decreased the incidence of early antibody mediated rejection(AMR) after +XMKTx. Post-transplant plasma exchange (PE) was not routinely used thus…2013 American Transplant Congress
Effect of the Purinergic Inhibitor Oxidized-ATP in a Model of Islet Allograft Rejection
The lymphocytic ionotropic purinergic P2X receptors (P2X1R-P2X7R, or P2Xs) sense the ATP, released during cell damage-activation, thus regulating T-cell activation. We aim to define the…